Barzooka - Fighting against bar graphs for continuous data!


Barzooka is a deep convolutional neural network that screens publication PDFs and checks for bar graphs of continuous data and other common graphing issues. Many different data distributions can lead to the same bar graph and the actual data may suggest different conclusions from the summary statistics alone. Barzooka also detects more informative alternatives to bar graphs, like dot plots, box plots and histograms. This website shows the detection of bar graphs for continuous data in bioRxiv preprints. A screening pipeline retrieves new preprints on a daily basis and screens them for bar graphs for continuous data. Preprints with bar graph detection are highlighted (column 'parse status') as well as the detected pages (click on 'View results'). Future interventions are planned to inform the authors of preprints about better alternatives for bar graphs.

View Results Title Date Posted Paper Link Parse Status Authors notified?
Anatomic development of the upper airway during the first five years of life: A three-dimensional imaging study
Notch signaling determines cell-fate specification of the two main types of vomeronasal neurons of rodents.
A novel role for the extraembryonic area opaca in positioning the primitive streak of the early chick embryo
Focal adhesion membrane is dotted with protein islands and partitioned for molecular hop diffusion
Cyclic uniaxial mechanical load enhances chondrogenesis through entraining the molecular circadian clock
Development of ultrafast camera-based imaging of single fluorescent molecules and live-cell PALM
Report of unexpected findings after cardiac stem cell injections in a preclinical model
The endoplasmic reticulum adopts two distinct tubule forms
Upregulated PD-1 Signaling is an Important Antagonist to Glomerular Health in Aged Kidneys
Changes in microbial composition, diversity, and functionality in the Amblyomma maculatum microbiome following infection with Rickettsia parkeri
Sensory prediction errors increase coding efficiency in mouse visual cortex through gain amplification
Adaptation of the gut holobiont to malnutrition during mouse pregnancy depends on the type of nutritional adversity
#PeerReview from @EMBOPress of ???????? Non-canonical activation of the ER stress sensor ATF6 by Legionella pneumophila effectors
Multi-omics analysis reveals cross-organism interactions in coral holobiont
Comprehensive analysis of the circadian nuclear and cytoplasmic transcriptome in mouse liver
ProS-GNN: Predicting effects of mutations on protein stability using graph neural networks
Disentangling single-cell omics representation with a power spectral density-based feature extraction
Bcl-xL restricts transcriptional, morphological and functional decompensation of β-cell mitochondria under chronic glucose excess
Aldehyde dehydrogenase 3A1 deficiency leads to mitochondrial dysfunction and impacts salivary gland stem cell self-renewal, differentiation and survival
The novel conserved NAD+ binding micropeptide SGHRT regulates mitochondrial function and metabolism in human cardiomyocytes
A basement membrane discovery pipeline uncovers network complexity, new regulators, and human disease associations
Activation of transient receptor potential vanilloid 4 is involved in pressure overload-induced cardiac hypertrophy
Epidermal Stratification Requires Retromer-Mediated Desmoglein-1 Recycling
The regenerative response of cardiac interstitial cells
Trisomy 21 increases microtubules and disrupts centriolar satellite localization
PU.1 expression defines distinct functional activities in the phenotypic HSC compartment in a mouse model of inflammatory stress
#PeerReview from @GigaScience of ???????? Detection and characterization of low and high genome coverage regions using an efficient running median and a double threshold approach.
Regulation of skeletal muscle metabolism and contraction performance via teneurin-latrophilin action.
Female choice can explain the fertilization pattern in oaks
Impact of Grain for Green Project on Water Resources and Ecological Water Stress in Yanhe River Basin
Alternative strategy to induce CRISPR-mediated genetic changes in hematopoietic cells
Profiling RT-LAMP tolerance of sequence variation for SARS-CoV-2 RNA detection
Estimated quantity of swine virus genomes based on quantitative PCR analysis in spray-dried porcine plasma samples collected from multiple manufacturing plants.
Effects of electroacupuncture on the expression of hypothalamic neuropeptide Y and ghrelin in pubertal rats with polycystic ovary syndrome
Multi-trait and multi-environment Bayesian analysis to predict the G x E interaction in flood-irrigated rice
In silico modeling and interactive profiling of BPH resistant R genes with elicitor molecules of rice planthoppers
#PeerReview from #GigaByte of ???????? Bicolor angelfish (Centropyge bicolor) provides the first chromosome-level genome of the Pomacanthidae family
Kinetic and data-driven modeling of pancreatic β-cell central carbon metabolism and insulin secretion
A suspension technique for efficient large-scale cancer organoid culturing and perturbation screens
Fast and parallel nanoscale 3D tracking of heterogeneous mammalian chromatin dynamics
Bicolor angelfish (Centropyge bicolor) provides the first chromosome-level genome of the Pomacanthidae family
Compatibility logic of human enhancer and promoter sequences
Density-dependent selection in Drosophila: evolution of egg size and hatching time
Stemness activity underlying whole brain regeneration in a basal chordate
A Prion that regulates genome diversification
Interleukin 7 receptor drives Early T lineage Progenitor expansion
Quercetin combined with Concanavalin A as a safe vaccine adjuvant that stimulates PBMCs proliferation, alleviates lipid peroxidation and boosts iNOS activity in the elderly.
Spatial coding in the hippocampus of flying owls
Cytidine deaminase protects pancreatic cancer cells from replicative stress and drives resistance to DNA-targeting drugs
Building tools for machine learning and artificial intelligence in cancer research: best practices and a case study with the PathML toolkit for computational pathology
Dynamics of lipids in the yeast lipid droplets
SINBAD: a flexible tool for single cell DNA methylation data
Assessment of Agaricus bisporus Mushroom as Protective Agent Against Ultraviolet Exposure
Quantification of breeding sites parameters in shaping bacterial communities in Aedes aegypti (Diptera: Culicidae).
Rapid decline in Western monarch butterflies leads to phenological and geographic Allee effects
ARP2/3- and resection-coupled genome reorganization facilitates translocations
Experimental microevolution of Trypanosoma cruzi reveals hybridization and clonal mechanisms driving rapid diversification of genome sequence and structure.
Discovery and Biosynthesis of Persiathiacins: Unusual Polyglycosylated Thiopeptides Active against Multi-drug resistant Tuberculosis
SARS-CoV-2 Infection Impacts Carbon Metabolism and Depends on Glutamine for Replication in Syrian Hamster Astrocytes
Protection from SARS-CoV-2 Delta one year after mRNA-1273 vaccination in nonhuman primates is coincident with an anamnestic antibody response in the lower airway
A transcriptomic axis predicts state modulation of cortical interneurons
Tsetse RNA Virome: Novel Iflavirus Genomes in Glossina morsitans and Other Tsetse Species
The humanized nanobody RBD-1-2G tolerates the spike N501Y mutation to neutralize SARS-CoV-2
NLR immune receptor-nanobody fusions confer plant disease resistance
Characterization of raloxifene as potential pharmacological agent against SARS-CoV-2 and its variants
The proteasome regulator PSME4 drives immune evasion and abrogates anti-tumor immunity in NSCLC
A focal adhesion kinase-YAP signaling axis drives drug tolerant persister cells and residual disease in lung cancer
Single-cell transcriptional analysis of the immune tumour microenvironment during myeloma disease evolution
Computational correction of cell-specific gene-independent effects in CRISPR-Cas9 essentiality screens: REStricted CUbic SplinEs with Mixed Models (RESCUE-MM)
ICA treatment diabets induced bone loss via primary cilia/Gli2/Osteocalcin signaling pathway
Inactivation of SARS Coronavirus 2 and COVID-19 patient samples for contemporary immunology and metabolomics studies
Multiple paths lead to salt tolerance - pre-adaptation vs dynamic responses from two closely related extremophytes
NanoSplicer: Accurate identification of splice junctions using Oxford Nanopore sequencing
Benchmarking AlphaFold for protein complex modeling reveals accuracy determinants
Oral administration of bacterial Beta cell expansion factor A (BefA) alleviates diabetes in mice with Type 1 and Type 2 diabetes
Excessive fetal growth affects HSC quiescence maintenance through epigenetic programming of EGR1 transcriptional network
Habitat determines convergent evolution of cephalic horns in vipers
The role of mitochondrial energetics in the origin and diversification of eukaryotes
Alternative Cdc20 translational isoforms bypass the spindle assembly checkpoint to control mitotic arrest duration
MRGM: a mouse reference gut microbiome reveals a large functional discrepancy for gut bacteria of the same genus between mice and humans
Previously uncharacterized rectangular bacteria in the dolphin mouth
Transcriptional regulation of photoprotection in dark-to-light transition - more than just a matter of excess light energy
ZELDA: a 3D Image Segmentation and Parent-Child relation plugin for microscopy image analysis in napari
Genomic insights into variation in thermotolerance between hybridizing swordtail fishes
Molecular basis of ocean acidification sensitivity and adaptation in Mytilus galloprovincialis
Flexible neural coding in sensory, parietal, and frontal cortices during goal-directed virtual navigation
Optimal confidence for unaware visuomotor deviations
Two structurally different oomycete MAMPs induce distinctive plant immune responses.
RAGE antagonist peptide mitigates AGE-mediated endothelial hyperpermeability and accumulation of glycoxidation products in human ascending aortas and in a murine model of aortic aneurysm
Sexual identity of enterocytes regulates rapamycin-mediated intestinal homeostasis and lifespan extension
Wiring multiple microenvironment proteomes uncovers the biology in head and neck cancer
Shared hotspot mutations in spontaneously arising cancers position dog as an unparalleled comparative model for precision therapeutics
A Developmentally Prometastatic Niche to Hepatoblastoma in Neonatal Liver mediated by the Cxcl1/Cxcr2 Axis
Classical Mathematical Models for Prediction of Response to Chemotherapy and Immunotherapy
The mechanosensitive TRPV2 calcium channel controls melanoma invasiveness and metastatic potential.
A noval lightsheet scattering microscopy for long-term visualization of cell-ECM interaction
Loss-of-function, gain-of-function and dominant-negative mutations have profoundly different effects on protein structure: implications for variant effect prediction
End-to-end learning of multiple sequence alignments with differentiable Smith-Waterman
Retinal self-organization: a model of RGC and SAC mosaic formation
DeePVP: Identification and classification of phage virion protein using deep learning
Accurate estimation of intrinsic biases for improved analysis of chromatin accessibility sequencing data using SELMA
Versatile Encapsulation and Synthesis of Potent Therapeutic Liposomes by Thermal Equilibration
Green notes: The rhythms of cyanobacteria exoelectrogenesis as de-composed by the Hilbert-Huang transform
Inference of cell state transitions and cell fate plasticity from single-cell with MARGARET
Drift on holey landscapes as a dominant evolutionary process
Structure and dynamics of Odinarchaeota tubulin and the implications for eukaryotic microtubule evolution
selscan 2.0: scanning for sweeps in unphased data
Disentangling the role of poultry farms and wild birds in the spread of highly pathogenic avian influenza virus H5N8 in Europe
NetGAM: Using generalized additive models to improve the predictive power of ecological network analyses constructed using time-series data
The epidemiology and genomics of a virulent emerging fungal pathogen in an Australian reptile
A Segmentation-Free Machine Learning Architecture for Immune Landscape Phenotyping in Solid Tumors by Multichannel Imaging
Verbena officinalis L. regulates killing efficiency of natural killer cells
Clostridioides difficile infection increases circulating p-cresol levels and dysregulates brain dopamine metabolism: linking gut-brain axis to autism and other neurologic disorders?
Generating accurate 3D gaze vectors using synchronized eye tracking and motion capture
The Listening Zone of Human Electrocorticographic Field Potential Recordings
An Unsupervised Machine Learning Paradigm for Artifact Removal from Electrodermal Activity in an Uncontrolled Clinical Setting
Fatigue induces behavioural improvements in the unfatigued hand via altered functional connectivity and neurochemicals in cortical motor areas
E-Cannula reveals anatomical diversity in sharp-wave ripples as a driver for the recruitment of distinct hippocampal assemblies
Decoding individualized motor cortical excitability states from whole-brain electroencephalography
Distribution of multi-unit pitch responses recorded intracranially from human auditory cortex
Visual occipito-temporal sensitivity to digits through elementary school
Hierarchical Bayesian Modeling of the Relationship between Task Related Hemodynamic Responses and Neuronal Excitability: a Simultaneous fNIRS/TMS Study
Quantitative fragmentomics allow affinity mapping of interactomes
Fine-tuning of RecBCD expression by post-transcriptional regulation is required for optimal DNA repair in Escherichia coli
Heterogeneity of Rift Valley fever virus transmission potential across livestock hosts, quantified through a model-based analysis of host viral load and vector infection
Altered collective mitochondrial dynamics in an Arabidopsis msh1 mutant compromising organelle DNA maintenance
Polar lipids are linked to nanoparticles in xylem sap of temperate angiosperm species
The behavioral effects of gestational and lactational benzo[a]pyrene exposure vary by sex and genotype in mice with differences at the Ahr and Cyp1a2 loci
Loss of epigenetic regulation disrupts lineage integrity, reactivatesmultipotency and promotes breast cancer
Extrachromosomal Amplification of Human Papillomavirus Episomes as a Mechanism of Cervical Carcinogenesis
scGAD: single-cell gene associating domain scores for exploratory analysis of scHi-C data
Dissecting tumor cell programs through group biology estimation in clinical single-cell transcriptomics
High-precision spatial analysis of mouse courtship vocalization behavior reveals sex and strain differences
transferGWAS: GWAS of images using deep transfer learning
Eurasian lynx populations in Western Europe: What prospects for the next 50 years?
Geographic distribution and future expansion of Aedes albopictus in the Democratic Republic of the Congo
Predominance of clonal propagation conceals extinction risks of the highly endangered floodplain herb Cnidium dubium
Multi-species mechanistic model of functional response provides new insights into predator-mediated interactions in a vertebrate community
Environmental DNA analysis needs local reference data to inform taxonomy-based conservation policy:A case study from Aotearoa / New Zealand
In-vitro cellular reprogramming to model gonad development and its disorders
Structural basis of malaria transmission blockade by a monoclonal antibody to gamete fusogen HAP2
Tickle contagion in the somatosensory cortex
Longitudinal single-cell transcriptional dynamics throughout neurodegeneration in SCA1
Oxytocin reduces interoceptive influences on empathy-for-pain in the anterior insula
Neural knowledge assembly in humans and deep networks
The many layers of BOLD. On the contribution of different vascular compartments to laminar fMRI.
Short term treatment with a cocktail of rapamycin, acarbose and phenylbutyrate slows aging in mice
A multiscale model of the cardiovascular system that incorporates baroreflex control of chronotropism, cell-level contractility, and vascular tone
Structural Knowledge Transfer of Panoptic Kidney Segmentation to Other Stains, Organs, and Species
Resistance to chemical carcinogenesis induction via a dampened inflammatory response in naked mole-rats
Real-Time Structure Search and Structure Classification for AlphaFold Protein Models
Evaluating test-retest reliability and sex/age-related effects on temporal clustering coefficient of dynamic functional brain networks
Crustacean cardiac ganglion model reveals constraints on morphology and conductances
Social mobility and biological aging among older adults in the United States
Developing a More Accurate Biomedical Literature Retrieval Method using Deep Learning and Citations in PubMed Central Full-text Articles
NAToRA, a relatedness-pruning method to minimize the loss of dataset size in genetic and omics analyses
Single Pulse Heating of Nanoparticle Array for Biological Applications
Developing a Biomimetic Evaluation Method for Antiviral Coatings Using Artificial Saliva Droplets.
A multi-variant recall-by-genotype study of the metabolomic signature of body mass index
Widespread anthropogenic translocation of the African Clawed Frog across its native range is revealed by its co-introduced monogenean parasite in a co-phylogeographic approach
Feature representation under crowding in V1 and V4 neuronal populations
Structure in motion: visual motion perception as online hierarchical inference
Impacts of dams on freshwater turtles: a global review to identify conservation solutions
Allosteric stabilization of calcium and lipid binding engages three synaptotagmins in fast exocytosis
Activity-dependent endoplasmic reticulum Ca2+ uptake depends on Kv2.1-mediated endoplasmic reticulum/plasma membrane junctions to promote synaptic transmission
Circadian programming of the ellipsoid body sleep homeostat in Drosophila
Spatiotemporal transcriptome at single-cell resolution reveals key radial glial cell population in axolotl telencephalon development and regeneration
Convergent energy state-dependent antagonistic signalling by CART and NPY modulates the plasticity of forebrain neurons to regulate feeding in zebrafish
Rapid Assessment of the Temporal Function and Phenotypic Reversibility of Neurodevelopmental Disorder Risk Genes in C. elegans
A positively Tuned Voltage Indicator Reveals Electrical Correlates of Calcium Activity in the Brain
Regulation of Neuroendocrine Plasticity by the RNA-Binding Protein ZFP36L1
Melanoma Addiction to GCDH is Mediated by NRF2 Tumor Suppressor Function
Symmetric Inheritance of Histones H3 in Drosophila Male Germline Stem Cell Divisions
Zika virus infection drives epigenetic modulation of immunity by the histone acetyltransferase CBP of Aedes aegypti
Kinetic principles underlying pioneer function of GAGA transcription factor in live cells
Amplicon sequencing of single-copy protein-coding genes reveals accurate diversity for sequence-discrete microbiome populations
Enterotoxigenic Escherichia coli degrades the host MUC2 mucin barrier to facilitate critical pathogen-enterocyte interactions in human small intestine.
Genotype-Phenotype Correlation of T Cell Subtypes Reveals Senescent and Cytotoxic Genes in Alzheimer's Disease
Safb1 regulates cell fate determination in adult neural stem cells by enhancing Drosha cleavage of NFIB mRNA
PermaPhosSer: autonomous synthesis of functional, permanently phosphorylated proteins
PRMT1 regulates EGFR and Wnt signaling pathways and is a promising target for combinatorial treatment of breast cancer
Breaking the Crosstalk of the Cellular Tumorigenic Network in NSCLC by a Highly Effective Drug Combination
Cancer cell-autonomous cGAS-STING response confers drug resistance
Conformational flexibility is a key determinant of the lytic activity of the pore forming protein, Cytolysin A
FABP7 Binds to Fatty Acid Micelles: Implications for Lipid Transport
Novel regulation of the transcription factor ZHX2 by N-terminal methylation
Potential genetic robustness of Prnp and Sprn double knockout mouse embryos towards ShRNA-lentiviral inoculation
The mechano-sensitive ion channel Piezo mediates Rho activation and actin stress fibre formation in Drosophila nephrocytes
A highly endemic area of Echinococcus multilocula is identified through a comparative re-assessment of prevalence in red fox (Vulpes vulpes), Alto Adige (Italy: 2019-2020)
A poxvirus decapping enzyme localizes to mitochondria to regulate RNA metabolism and translation, and promote viral replication
A Goldilocks Principle for the Gut Microbiome: Taxonomic Resolution Matters for Microbiome-Based Classification of Colorectal Cancer
The Wolbachia CinB Nuclease is Sufficient for Induction of Cytoplasmic Incompatibility
Cytosolic Sensor of Bacterial Lipopolysaccharide in Human Macrophages
Dynamic Cell Imaging: application to the diatom Phaeodactylum tricornutum under environmental stresses
Retraction ATPase motors are promiscuous among type IVa pilus systems
Naturally acquired antibody kinetics against Plasmodium vivax antigens in people from a low malaria transmission region in western Thailand
Nanoviricides Platform Technology based NV-387 polymer Protects Remdesivir from Plasma-Mediated Catabolism in vitro:Importance of its increased lifetime for in vivo action
Hippocampal spatio-temporal cognitive maps adaptively guide reward generalization
Variations in cell-surface ACE2 levels alter direct binding of SARS-CoV-2 Spike protein and viral infectivity: Implications for measuring Spike protein interactions with animal ACE2 orthologs
Developmental Dynamics of RNA Translation in the Human Brain
Reduced context updating but intact visual priors in autism
A CRISPR-Cas9-based system for the dose-dependent study of DNA double strand breaks sensing and repair
Disruption of Epithelial Integrity Drives Mesendoderm Differentiation in Human Induced Pluripotent Stem Cells by Enabling BMP and ACTIVIN Sensing
S1P controls endothelial sphingolipid homeostasis via ORMDL
Higher synaptic threshold for NMDA spike generation in human neurons
Motor processivity and speed determine structure and dynamics of microtubule-motor assemblies
MutS and DNA Function as a Clamp Loader for the MutL Sliding Clamp During Mismatch Repair
Coordinated DNA and Histone Dynamics Drive Accurate Histone H2A.Z Exchange
Innexin function dictates the spatial relationship between distal somatic cells in the Caenorhabditis elegans gonad without impacting the germline stem cell pool
The post-transcriptional regulation of TFs in immature motoneurons shapes the axon-muscle connectome
Trap-TRAP, a versatile tool for tissue-specific translatomics in zebrafish
The Rpd3-complex regulates expression of multiple cell surface recycling factors in yeast
Single-particle tracking of dynein identifies PP2A B55/SUR-6 as a cell cycle regulator of cortical force generation
Building new compartments for unconventional protein secretion from the early and late Golgi membranes
Hingepoint emergence in mammalian spinal neurulation
Non-glycosylated Seipin to Cause a Motor Neuron Disease Induces ER stress and Apoptosis by Inactivating the ER Calcium Pump SERCA2b
A model that predicts resistant starch in a dog kibble using a small-scale twin-screw extruder
Molecular Insights into the Differential Dynamics of SARS-CoV-2 Variants of Concern (VOCs)
Underlying selection for the diversity of Spike protein sequences of SARS-CoV-2
Modeling microRNA-driven post-transcriptional regulation by using exon-intron split analysis (EISA) in pigs
Total evidence tip-dating phylogeny of platyrrhine primates and 27 well-justified fossil calibrations for primate divergences
Autopolyploid establishment depends on life history strategy and the mating outcomes of clonal architecture
Gramicidin S and Melittin - Potential anti-viral therapeutic peptides to treat SARS-CoV-2 infection
Nasal prevention of SARS-CoV-2 infection by intranasal influenza-based boost vaccination
De novo motor learning of a bimanual control task over multiple days of practice
High-frequency hearing is required for generating a topographic map of auditory space in the mouse superior colliculus
Proteomic analysis of mouse kidney tissue associates peroxisomal dysfunction with early diabetic kidney disease
Formulation of Dry Powders of Vaccines Containing MF59 or AddaVax by Thin-Film Freeze-Drying
The SAMBA tool uses long reads to improve the contiguity of genome assemblies
Morphology and gene expression profiling provide complementary information for mapping cell state
Novel algorithms deriving clinical performance measures from smartphone sensor data collected under a walking test
Within-generation and transgenerational social plasticity interact during rapid adaptive evolution
Hydraulic synchrony of spawning sites amongst Earth's riverine fishes
A molecular switch between mammalian MLL complexes dictates response to Menin-MLL inhibition
Hybridisation and chloroplast capture between ancient Themeda triandra ecotypes in Australia
The natural history of the black soldier fly, Hermetia illucens: insights from complete mitochondrial genome sequences
Sex differences in the strength of selection under facultative sex
Pupillometry and electroencephalography in the digit span task
Use-dependent biases primarily originate from a contaminated motor plan
The human frontal operculum is involved in visuomotor performance monitoring
Early detection of cerebrovascular pathology and protective antiviral immunity by MRI
Neuropeptide Neuromedin B does not alter body weight and glucose homeostasis nor does it act as an insulin-releasing peptide
Mimicked synthetic ribosomal protein complex for benchmarking cross-linking mass spectrometry workflows
A comprehensive benchmark for structural assessment in bipartite networks
Systematic reduction of the dimensionality of natural scenes allows accurate predictions of retinal ganglion cell spike outputs.
Readers move their eyes mindlessly using midbrain visuo-motor principles
An in-vivo digital atlas of the spatially reliable cerebral vasculature in mice
Visualization of Sympathetic Neural Innervation in Human White Adipose Tissue
The 2D Ising model, criticality and AIT
Learning the statistics of pain: computational and neural mechanisms
Roosting ecology and the evolution of bat landing maneuvers
ChemChaste: Simulating spatially inhomogenous biochemical reaction-diffusion systems for modelling cell-environment feedbacks
Incorporating Target-Specific Pharmacophoric Information Into Deep Generative Models For Fragment Elaboration
Effect of reversible osmotic stress on live cell plasma membranes, probed via Laurdan general polarization measurements
Implementation of residue-level coarse-grained models in GENESIS for large-scale molecular dynamics simulations
Non-monotonic fibril surface occlusion by GFP tags from coarse-grained molecular simulations
Habitat loss exacerbates pathogen spread: An Agent-based model of avian influenza infection in migratory waterfowl
High-resolution spatiotemporal transcriptomic maps of developing Drosophila embryos and larvae
Spatiotemporal mapping of gene expression landscapes and developmental trajectories during zebrafish embryogenesis
Myosin-X-dependent assembly of the extracellular matrix limits breast cancer invasion
Aurora B/C-dependent phosphorylation promotesRec8 cleavage in mammalian oocytes
Automated and parallelized spike collision tests to identify spike signal projections
Spatially-resolved transcriptomics analyses of invasive fronts in solid tumors
3D visualisation of the cardiac ryanodine receptor clusters and the molecular-scale fraying of dyads
Colour Vision in Stomatopod Crustaceans: more questions than answers
Systematic analysis of intrinsic enhancer-promoter compatibility in the mouse genome.
Structural anther mimics improve reproductive success through dishonest signalling that enhances both attraction and the morphological fit of pollinators with flowers
Microbial stowaways - waterbirds as dispersal vectors of aquatic pro- and microeukaryotic communities
Thioflavin T indicates membrane potential in mammalian cells and can affect it in a blue light dependent manner.
Hyperphosphatemia increases inflammation to exacerbate anemia and skeletal muscle wasting independently of FGF23-FGFR4 signaling
Contribution of cytoplasm viscoelastic properties to mitotic spindle positioning
Potassium-chelating drug sodium polystyrene sulfonate enhances lysosomal function and suppresses proteotoxicity
Actin filaments act as a size-dependent diffusion barrier around centrosomes
A Null Allele of the Pol IV Second Subunit is Viable in Oryza sativa
fcfdr: an R package to leverage continuous and binary functional genomic data in GWAS
Unlocking the functional potential of polyploid yeasts
Moran Process Version of the Tug-of-War Model: Complex Behavior Revealed by Mathematical Analysis and Simulation Studies
Escherichia coli ribosomal protein S1 enhances the kinetics of ribosome biogenesis and RNA decay
Cytotoxic CD4+ T cells driven by T-cell intrinsic IL-18R/MyD88 signaling predominantly infiltrate Trypanosoma cruzi-infected hearts
Can intraspecific variation in a herbivorous mite alter responses to drought-stressed host plant? A common garden experiment in the context of climate change
Cytometric Analysis of Diverse Glaucophyte Species Reveals Distinctive Signals Useful for Fluorescence-Based Detection and Sorting
Mitochondrial fission process 1 (MTFP1) controls bioenergetic efficiency and prevents inflammatory cardiomyopathy and heart failure in mice
Mining of thousands of prokaryotic genomes reveals high abundance of prophage signals
Defining cellular complexity in human autosomal dominant polycystic kidney disease by multimodal single cell analysis
Generation and characterization of Ccdc28b mutant mice links the Bardet-Biedl associated gene with social behavioral phenotypes
A pathogenic fungus uses volatiles to entice male flies into fatal matings with infected female cadavers
The uptake of avermectins in Caenorhabditis elegans is dependent on Intra-Flagellar Transport and other protein trafficking pathways
Non-motile subpopulations of Pseudomonas aeruginosa repress flagellar motility in motile cells through a type IV pili- and Pel-dependent mechanism
Expression of brain-derived neurotrophic factor in basolateral amygdala inputs to lateral septum is necessary for mice to identify socially novel individuals
PI4P and BLOC-1 remodel endosomal membranes into tubules
SiglecFhigh neutrophils in lung tumor tissues suppress local CD8 T cell responses and limit the efficacy of anti PD-L1 antibodies
Conserved Structure Modules within the lncRNA SChLAP1 Mediate Protein Recognition Implicated in Aggressive Prostate Cancer
Structural basis for long-chain isoprenoids synthesis by cis-prenyltransferases
A holistic insight of mycobacteriophage induced changes in mycobacterial cells
Impact of various preservation and storage methods on the viability of mycoplasma field strains isolated in Mali
Survey evaluation of dog owners feeding habits in a household setting and comparison of FDA hygiene protocols on dog bowl bacterial contamination as evaluated by total aerobic cell counts.
Thalamus gates active dendritic computations in cortex during sensory processing
Unravelling the role of thyroid hormones in seasonal neuroplasticity in European Starlings (Sturnus vulgaris)
Temporal pattern recognition in the human brain: a dual simultaneous processing
Probing behavior of the corn leafhopper Dalbulus maidis on susceptible and resistant maize hybrids
The amount range of membrane cholesterol required for robust cell adhesion and proliferation in serum-free condition.
Mining transcriptomic data to identify Saccharomyces cerevisiae signatures related to improved and repressed ethanol production under fermentation
Influences of rare copy number variation on human complex traits
Defining Cardiac Cell Populations and Relative Cellular Composition of the Early Fetal Human Heart
Diversification of multipotential postmitotic mouse retinal ganglion cell precursors into discrete types
BRCA1 and ELK-1 regulate Neural Progenitor Cell Fate in the Optic Tectum in response toVisual Experience in Xenopus laevis tadpoles
Differential effects of Wnt-β-catenin signaling in Purkinje cells and Bergmann glia in SCA1
Temperature-dependent local conformations and conformational distributions of cyanine dimer labeled single-stranded -- double-stranded DNA junctions by 2D fluorescence spectroscopy
The HIV-1 Integrase C-Terminal domain induces TAR RNA structural changes promoting Tat binding.
Maternal SMCHD1 controls both imprinted Xist expression and imprinted X chromosome inactivation
Haemocytes are critical for Drosophila melanogaster post-embryonic development, independent of control of the microbiota
Cooperative Effects of RIG-I-like Receptor Signaling and IRF1 on DNA Damage-Induced Cell Death
Engineering transcription factor BmoR mutants for constructing multifunctional alcohol biosensors
Commensal bacteria promote type I interferon signaling to maintain immune tolerance
A novel Pan-viral prophylaxis strategy using vaccine adjuvant CAF09b protects against influenza virus infection
TAL effectors with avirulence activity in African strains of Xanthomonas oryzae pv. oryzae
The Mettl3 epitranscriptomic writer amplifies p53 stress responses
Effects of Oncohistone Mutations and PTM Crosstalk on the N-terminal Acetylation Activities of NatD
The Formation of a Stable Sliding Clamp Discriminates MSH2-MSH3 and MSH2-MSH6 Mismatch Interaction
Sequence Recognition by a Pseudorotational Cycle of Sugar Puckers: A Base Pair Switching Model via N-E Sugar Pucker Conversion for Homologous Recombination
Multi-omics analysis identifies a CYP9K1 haplotype conferring pyrethroid resistance in the malaria vector Anopheles funestus in East Africa
Population genomics of ancient and modern Trichuris trichiura
DNA-PK Promotes DNA End Resection at DNA Double Strand Breaks in G0 cells
Massively parallel identification of zipcodes in primary cortical neurons
DOT1L bridges transcription and heterochromatin formation at pericentromeres
S100A8 and S100A9, biomarkers of SARS-Cov-2-infected patients, suppress HIV replication in primary macrophages
BglC of Streptomyces scabiei is a scopolin-hydrolyzing β-glucosidase interfering with the host defense mechanism
A patatin-like phospholipase mediates Rickettsia parkeri escape from host membranes
SOCS3-mediated activation of p53-p21-NRF2 axis and cellular adaptation to oxidative stress in SOCS1-deficient hepatocellular carcinoma
Unravelling the Graded Millisecond Allosteric Activation Mechanism of Imidazole Glycerol Phosphate Synthase
Translocation of polyubiquitinated protein substrates by the hexameric Cdc48 ATPase
Single-cell Atlas Unveils Cellular Heterogeneity and Novel Markers in Human Neonatal and Adult Intervertebral Discs
A Recombinant Multivalent Vaccine (rCpa1) Induces Protection for C57BL/6 and HLA Transgenic Mice Against Pulmonary Infection with Both Species of Coccidioides
Plasticity of Neural Connections Underlying Oxytocin-mediated Parental Behaviors of Male Mice
What can astrocytes compute?
PyDesigner: A Pythonic Implementation of the DESIGNER Pipeline for Diffusion Tensor and Diffusional Kurtosis Imaging
Single-cell Stereo-seq enables cell type-specific spatial transcriptome characterization in Arabidopsis leaves
Engineering A Fluorescent Protein Color Switch Using Entropy-driven Beta Strand Exchange
Markerless mouse tracking for social experiments
Severe fever with thrombocytopenia syndrome virus and parthenogenetic Asian longhorned tick Haemaphysalis longicornis (Acari: Ixodidae)
Microplastic pollution of commercial fishes from coastal and offshore waters, Japan
Cell responses to simulated microgravity and hydrodynamic stress can be distinguished by using comparative transcriptomic analysis
Diamond Raman Laser and Yb Fiber Amplifier for In Vivo Multiphoton Fluorescence Microscopy
Loss of C9orf72 perturbs the Ran-GTPase gradient and generates compositionally diverse cytoplasmic Importin β-1 granules in motor and cortical neurons in vivo
Endoplasmic Reticulum Chaperone Genes Encode Effectors of Long-Term Memory
The Carotid Body Detects Circulating Tumor Necrosis Factor-Alpha to Activate a Sympathetic Anti-Inflammatory Reflex
GAMES: A dynamic model development workflow for rigorous characterization of synthetic genetic systems
Encapsulated actomyosin patterns drive cell-like membrane shape changes
Deep learning models for identifying crop and field attributes from near surface cameras
Arabidopsis PROTODERMAL FACTOR2 binds lysophosphatidylcholines and transcriptionally regulates phospholipid metabolism
3D-mapping of human lymph node and spleen reveals integrated neuronal, vascular, and ductal cell networks
A Biologically Plausible Model for Continual Learning using Synaptic Weight Attractors
A transcriptional constraint mechanism limits the homeostatic response to activity deprivation in mammalian neocortex
Systematic expression profiling of dprs and DIPs reveals cell surface codes in Drosophila larval peripheral neurons
Alpha-synuclein is present in the nucleus in human brain tissue and is pathologically modified in Dementia with Lewy Bodies
NOXA expression drives synthetic lethality to RUNX1 inhibition in pancreatic cancer
Is the Success of Adaptive Therapy in Metastatic Castrate Resistant Prostate Cancer Influenced by Cell-Type-Dependent Production of Prostate Specific Antigen?
Who takes care of the kids at when? Variation of sex-role patterns across different parental care forms in passerine birds
A tiger in the Upper Midwest: Surveillance and genetic data support the introduction and establishment of Aedes albopictus in Iowa, USA
Sponge contribution to the silicon cycle of a diatom-rich shallow bay
A multimodal imaging and analysis pipeline for creating a cellular census of the human cerebral cortex
Fibrosis protein-protein interactions from Google matrix analysis of MetaCore network
Regulation of protein secretion through chemical regulation of endoplasmic reticulum retention signal cleavage
Combinatorial tumor suppressor inactivation efficiently initiates lung adenocarcinoma with therapeutic vulnerabilities
Spatial transcriptomics reveals the two cancer stem cell-like populations in triple-negative breast cancer
Pre-neoplastic stromal cells drive BRCA1-mediated breast tumorigenesis
REViewer: Haplotype-resolved visualization of read alignments in and around tandem repeats
Yn-situ: a robust single RNA molecule in situ detection method
Pavlovian fear conditioning does not readily occur in rats in naturalistic environments
Rating enrichment items by group-housed laboratory mice in multiple binary choice tests using an RFID-based tracking system
Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells
Dual domestication, diversity, and differential introgression in Old World cotton diploids
Plant organic matter inputs exert a strong control on soil organic matter decomposition in a thawing permafrost peatland
Soil viral communities are structured by pH at local and global scales
The endophilin curvature-sensitive motif requires electrostatic guidance to recycle synaptic vesicles in vivo
Systematic identification of yeast mutants with increased rates of cell death reveals rapid stochastic necrosis associated with cell division
Persistent synaptic inhibition of the subthalamic nucleus by high frequency stimulation
Highly efficient generation of canker resistant sweet orange enabled by an improved CRISPR/Cas9 system
Spatiotemporal solidification of α-synuclein inside the liquid droplets
Cryo-EM structures of pentameric autoinducer-2 exporter from E. coli reveal its transport mechanism
Organic electrolytic photocapacitors for stimulation of the mouse somatosensory cortex
Evidence for a conserved queen-worker genetic toolkit across slave-making ants and their ant hosts
Coral settlement and recruitment responses to reef fish foraging and trait diversity
Arnold tongue entrainment reveals dynamicalprinciples of the embryonic segmentation clock
Optogenetic activation of basolateral amygdala projections to nucleus accumbens core promotes cue-induced expectation of reward but not instrumental pursuit of cues
Tropical-temperate dichotomy falls apart in the Asian Palmate Group of Araliaceae
CPExtract, a Software for the Automated Tracer-Based Pathway Specific Screening of Secondary Metabolites in LC-HRMS Data
Lift the Veil of Breast Cancers Using Four or Fewer Critical Genes
A Network-based Deep Learning Framework Catalyzes GWAS and Multi-Omics Findings to Biology and Drug Repurposing for Alzheimer's Disease
hyperTRIBER: a flexible R package for the analysis of differential RNA editing
Structural convergence for tubulin binding of CPAP and vinca domain microtubule inhibitors
Natural variation further increases resilience of sorghum bred for chronically drought-prone environments
Transcriptome profiling of the ventral pallidum reveals a role for pallido-thalamic neurons in cocaine reward
Signatures of Brain Network Alteration in Psychogenic Non-Epileptic Seizures: A Rest-EEG Study Based on Power Spectral Density and Phase Lag Index
Phospho-regulation accommodates Type III secretion and assembly of a tether of ER-Chlamydia inclusion membrane contact sites
Heterogeneous Tfh cell populations that develop during enteric helminth infection predict the quality of type 2 protective response
Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations
Molecular pathology of a cystic fibrosis mutation is explained by loss of a hydrogen bond
CLUH controls astrin-1 expression to couple mitochondrial metabolism to cell cycle progression
Immortalization and Functional Screening of Natively Paired Human T Cell Receptor Repertoires
Regulatory variants active in iPSC-derived pancreatic progenitor cells are associated with Type 2 Diabetes in adults
Downregulation of RyR and NCX in the neonatal rat ventricular myocyte modulates cytosolic [Ca2+]
MS2 RNA aptamer enhances prime editing in rice
Adrenergic signaling controls early transcriptional programs during CD8+ T cell responses to viral infection
Long-range regulatory effects of Neandertal DNA in modern humans
How development affects evolution
Combination of structural and functional connectivity explains unique variation in specific domains of cognitive function.
Abstract representations emerge naturally in neural networks trained to perform multiple tasks
Executive and Attentional Resting-State Hubs of the Human Cortical Connectome Revealed by a Causal Discovery Method for Data-Driven Effective Connectivity Analysis
The superior salinity tolerance of wheat cultivar Shanrong No. 3 cannot be attributed to elevated Ta-sro1 poly(ADP-ribose) polymerase activity
Locational memory of macrovessel vascular cells is transcriptionally imprinted
Dlk1-Dio3 cluster miRNAs regulate mitochondrial functions in Duchenne muscular dystrophy
Autophagy-dependent TOR reactivation drives fungal growth in living host rice cells
A Tissue-Bioengineering Strategy for Modeling Rare Human Kidney Diseases In Vivo
Dynamic chromosomal interactions and control of heterochromatin positioning by Ki67
Genome-wide distribution of Rad26 and Rad1-Rad10 reveals their relationship with Mediator and RNA polymerase II
The Polo kinase Cdc5 is regulated at multiple levels in the adaptation response to telomere dysfunction
HiIDDD: A high-throughput imaging pipeline for the quantitative detection of DNA damage in primary human immune cells
Lysosomes dock to omegasomes and ER-connected Phagophores During DNAJB12 and GABARAP-Dependent Selective-Autophagy of Misfolded P23H-Rhodopsin
Cholesterol biosynthetic pathway induces cellular senescence through ERRa
C/EBPα acts as an RNA binding protein essential for its chromatin recruitment and promotes Macrophage differentiation
Limited specificity of molecular interactions incurs an environment-dependent fitness cost in bacteria
Nutritional dependence of sperm mitochondrial metabolism and small RNA biogenesis
In vitro analysis of the effects of acetaminophen, ibuprofen and aspirin on motility of female adult Onchocerca volvulus worms
Human milk oligosaccharides reduce murine group B Streptococcus vaginal colonization with minimal impact on the vaginal microbiota
CRISPR-Cas9 mediated knockout of SagD gene for overexpression of streptokinase in Streptococcus equisimilis
A novel innate pathogen sensing strategy involving ubiquitination of bacterial surface proteins
Metastatic profiling of HER2-positive breast cancer cell lines in xenograft models
DNA double-strand break end synapsis by DNA loop extrusion
Structural Basis for the Inhibition of IAPP Fibril Formation by the Hsp60 Co-Chaperonin Prefoldin
High-throughput identification of RNA localization elements reveals a regulatory role for A/G rich sequences
Deep mining of the Sequence Read Archive reveals bipartite coronavirus genomes and inter-family Spike glycoprotein recombination
Global diversity and distribution of prophages is lineage-specific within the Ralstonia solanacearum plant pathogenic bacterium species complex
Post-entry, spike-dependent replication advantage of B.1.1.7 and B.1.617.2 over B.1 SARS-CoV-2 in an ACE2-deficient human lung cell line
An intranasally administrated SARS-CoV-2 beta variant subunit booster vaccine prevents beta variant viral replication in rhesus macaques
Microtubule dynamics and the evolution of mitochondrial populations in fission yeast cells: A kinetic Monte Carlo study
Discovery of Potent Triple Inhibitors of Both SARS-CoV-2 Proteases and Human Cathepsin L
Parameter Sensitivity and Experimental Validation for Fractional-Order Dynamical Modeling of Neurovascular Coupling
Characterization of adenine phosphoribosyltransferase (APRT) activity in Trypanosoma brucei brucei: only one of the two isoforms is kinetically active
Inhibition of adrenergic b1-AR/Gas signaling promotes cardiomyocyte proliferation through activation of RhoA-YAP axis
Transcriptome data from human nasal epithelial cells infected by H3N2 influenza virus indicate early unbalanced ROS/RNA levels, temporarily increased aerobic fermentation linked to enhanced α-tubulin and rapid ...
Major complex trait for early de novo programming 'CoV-MAC-TED' detected in human nasal epithelial cells infected by two SARS-CoV-2 variants is promising for designing therapeutic strategies
The unique pattern of mannose-capped lipoarabinomannan expression in Mycobacterium tuberculosis with different drug resistant profiles following isoniazid stress
Neutralization of Mu and C.1.2 SARS-CoV-2 Variants by Vaccine-elicited Antibodies in Individuals With and Without Previous History of Infection
Preparation of ingestible antibodies to neutralize the binding of SarsCoV2 RBD (receptor binding domain) to human ACE2 Receptor
The anterior insular cortex associates temporally discontiguous stimuli during threat learning
Repurposed nystatin to inhibit SARS-CoV-2 and mutants in the GI tract
Identifying the oncogenic potential of gene fusions exploiting miRNAs
A quantitative comparison of human embryonic and induced stem cell proteomes
Novel torin1-sensitive phosphorylation sites on the metabolic regulator AMPK revealed by label-free mass spectrometry
The Effects of Prenatal Nicotine and THC E-Cigarette Exposure on Motor Development in Rats
Intensive Single Cell Analysis Reveals Immune Cell Diversity among Healthy Individuals
Evolutionary trade-offs between heat and cold tolerance limit responses to fluctuating climates
Valuation of carbon services produced by wild animals finances conservation
Characterising the vegetation-rainfall relationship in the Northeast Himalaya, India
S-phase induced RNAs initiate formation of DNA replication origins
Cellular adhesion is a controlling factor in neutrophil extracellular trap formation induced by antineutrophil cytoplasmic antibodies
Identification of novel therapeutic targets for polyglutamine toxicity disorders that target mitochondrial fragmentation
Cortico-Subcortical Interactions in Overlapping Communities of Edge Functional Connectivity
On the prediction of human intelligence from neuroimaging: A systematic review of methods and reporting
Periodic and Aperiodic Neural Activity Displays Age-Dependent Changes Across Early-to-Middle Childhood
The miR-124-AMPAR pathway connects polygenic risks with behavioral changes shared between schizophrenia and bipolar disorder
Feature blindness: a challenge for understanding and modelling visual object recognition
Modelling altered signalling of G-protein coupled receptors in inflamed environment to advance drug design
OsMADS58 stabilizes gene regulatory circuits during rice stamen development
Interspecific divergence of circadian properties in duckweed plants
Exit from quiescence couples epithelial stress amplification to fluidization
Structural identification of individual helical amyloid filaments by integration of cryo-electron microscopy-derived maps in comparative morphometric atomic force microscopy image analysis
Nuclear import and chaperoning of monomeric histones H3 and H4 is mediated by Imp5, NASP and the HAT1 complex
Pseudomonas aeruginosa cytochrome P450 CYP168A1 is a fatty acid hydroxylase that metabolizes arachidonic acid to the vasodilator 19-HETE
Untwisted α-synuclein Filaments formed in the Presence of Lipid Vesicles
Escherichia coli strains from patients with inflammatory bowel diseases have disease-specific genomic adaptations
Multi-hallmark long noncoding RNA maps reveal non-small cell lung cancer vulnerabilities
Global distribution of mammal herbivore biomass reveals megafauna extinction patterns
A kinesin-1 variant reveals motor-induced microtubule damage in cells
Influence of DNA extraction kits on the fungal DNA metabarcoding for freshwater environmental DNA
T cell receptor and IL-2 signaling strength control memory CD8+ T cell functional fitness via chromatin remodeling
Differences in spike generation instead of synaptic inputs determine the feature selectivity of two retinal cell types.
Pupil Dilation and Response Slowing Distinguish Deliberate Explorative Choices in the Probabilistic Learning Task
Activation of SGK1.1 up-regulates the M-current in the presence of epilepsy mutations
Genetic and genomic architecture of species-specific cuticular hydrocarbon variation in parasitoid wasps
Uncovering the Genetic Architecture of Broad Antisocial Behavior through a Genome-Wide Association Study Meta-analysis.
Triazolopyrimidines target aerobic respiration in Mycobacterium tuberculosis
Theta coordinates hippocampal-entorhinal ensembles during wake and rest
Cables1 links Slit/Robo and Wnt/Frizzled signaling in commissural axon guidance
Language experience shapes music processing across 40 tonal, pitch-accented, and non-tonal languages
Integrative system biology analysis of barley transcriptome - hormonal signaling against biotic stress
Driving singing behaviour in songbirds using multi-modal, multi-agent virtual reality
Hysteresis in PIF4 and ELF3 dynamics dominates warm daytime memory in Arabidopsis
Cross-border investigations on the prevalence and transmission dynamics of Cryptosporidium species in dairy cattle farms in western mainland Europe
A Computational Approach in Identification of Putative Risk Genes in Parkinsons Disease
BioCompute Objects to communicate a viral detection pipeline with potential for use in a regulatory environment
ZipHiC: a novel Bayesian framework to identify enriched interactions and experimental biases in Hi-C data
Expanding the pool of public controls for GWAS via a method for combining genotypes from arrays and sequencing
KIMGENS: A novel method to estimate kinship in organisms with mixed haploid diploid genetic systems robust to population structure
Novel graph theoretic biological pathway network analytics methods for analyzing and discovering Alzheimer's disease related genes
Ligand geometry dictates cellular and in vivo uptake of 3D DNA nanostructures
CandyCollect: At-home saliva sampling for respiratory pathogen capture
Freestanding Hydrogel Lumens for Biological Assays
Machine Learning Prediction of Non-Coding Variant Impact in Human Retinal Cis-Regulatory Elements
A within-host infection model to explore tolerance andresistance
Multiple Sex Chromosome Drivers in a Mammal with Three Sex Chromosomes
Facing the green threat: A waterflea's defenses against a carnivorous plant
Similar geographic patterns but distinct assembly processes of abundant and rare bacterioplankton communities in river networks of the Taihu Basin
Single-Cell Analysis of Human Testis Aging, and Impact of Elevated Body Mass Index
Sculpting rupture-free nuclear shapes in fibrous environments
Two type II phosphatidylinositol 4-kinases function sequentially in tubule-mediated cargo delivery from early endosomes to melanosomes
A single-cell approach reveals variation in cellular phage-producing capacities
Contribution of rsaC, a small non-coding RNA, towards the pathogenicity of Staphylococcus aureus in a mouse systemic infection model
Clonally expanded CD38hi cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor-associated arthritis
Expression level of the reprogramming factor NeuroD1 is critical for neuronal conversion efficiency from different cell types
Quantitative MRI reveals differences in striatal myelin in children with DLD
Visual Motion Coherence Responses in Human Visual Cortex
Neural network embedding of functional microconnectome.
Overground Gait Kinematics and Muscle Activation Patterns in the Yucatan Mini Pig
CombPDX: a unified statistical framework for evaluating drug synergism in patient-derived xenografts
Base editors for citrus gene editing
Tuning the Pennes Perfusion Rate to Model Large Vessel Cooling Effects in Hepatic Radiofrequency Ablation
Analysing and identifying miRNAs from RNA-seq data using miRDeep2 tool in Galaxy, a practical guide.
Chromosome-encoded IpaH ubiquitin ligases indicate non-human pathogenic Escherichia
In vitro experiments and kinetic models of pollen hydration show that MSL8 is not a simple tension-gated osmoregulator
Interaction of human Crx and Nrl in live cells measured using fluorescence resonance energy transfer (FRET)
Specificities and commonalities of carbapenemase producing Escherichia coli isolated in France from 2012 to 2015.
Expert annotation and life-cycle transcriptomics of transcription factors in rust fungi (Pucciniales) highlight the role of cold shock proteins in dormancy exit
Cyclooxygenase production of PGE2 promotes phagocyte control of A. fumigatus hyphal growth in larval zebrafish
Single cell transcriptomics reveals distinct effector profiles of infiltrating T cells in lupus skin and kidney
Genetic Mouse Models of Autism Spectrum Disorder Present Subtle Heterogenous Cardiac Abnormalities.
Controlling Selectivity of Modular Microbial Biosynthesis of Butyryl-CoA-Derived Designer Esters
Design, 3D-printing, and characterisation of a low-cost, open-source centrifuge adaptor for separating large volume clinical blood samples
In an arms race between host and parasite, a lungworm's ability to infect a toad is determined by host susceptibility, not parasite preference
Overexpression of Zinc finger (GpZF) promotes drought tolerance in grass pea (Lathyrus sativus)
Systematic Discovery of Antimicrobial Polymorphic Toxins
Chikungunya virus vaccine candidate incorporating synergistic mutations is attenuated and protects against virulent virus challenge
The hallucinogenic serotonin2A receptor agonist, DOI, promotes CREB-dependent gene expression of specific plasticity-associated genes in the rodent neocortex
Opposing subclasses of Drosophila ellipsoid body neurons promote and suppress sleep
Fetal neural progenitors process TLR signals from bacterial components to enhance proliferation and rework brain development
Identification of bacterial drug-resistant cells by the convolutional neural network in transmission electron microscope images
Combinatorial transcriptional codes specify macrophage polarization destinations
HaHB11 transformed maize has improved yield under waterlogging and defoliation in control and field conditions
Interleukin-1 is overexpressed in injured muscles following spinal cord injury and promotes neurogenic heterotopic ossification
Observation of reversal in twist-stretch coupling of RNA suggests a unified mechanism for the opposite couplings of DNA and RNA
Diverse chemical functionalization of nucleobases within long RNAs using sulfinate salts
A dual involvement of Protocadherin-18a in stromal cell development guides the formation of a functional hematopoietic niche.
Antennapedia regulates metallic silver wing scale development and cell shape in Bicyclus anynana butterflies
Resolving the 3D rotational and translational dynamics of single molecules using radially and azimuthally polarized fluorescence
Nanoscale organization of ryanodine receptor distribution and phosphorylation pattern determines the dynamics of calcium sparks
Restoration of a pond: monitoring water quality and macroinvertebrate community succession
Dynamic proton-dependent motors power Type IX secretion and gliding adhesin movement in Flavobacterium
Survival of hatchery grown native oysters is associated with specific gut-associated bacteria at various locations within the Puget Sound
Sonic Hedgehog Pathway Modulation Normalizes Expression of Olig2 in Rostrally Patterned NPCs with Trisomy 21
Dynamic Brain Network States during Suspenseful Film Viewing
The landscape of extrachromosomal circular DNA in medulloblastoma
ADAR2-repressed RNA editing: a novel mechanism contributing to t (8:21) AML leukemogenesis
VSS-Hi-C: Variance-stabilized signals for chromatin 3D contacts
High Resolution Nanostructure with Two-stages of Exponential Energy Dissipation at the Ultrathin Osteochondral Interface Tissue of Human Knee Joint
Rapid and Effective Inactivation of SARS-CoV-2 by a Cationic Conjugated Oligomer with Visible Light: Studies of Antiviral Activity in Solutions and on Supports
An improved vector for baculovirus-mediated protein production in mammalian cells
Negative catalysis by the editing domain of class I aminoacyl-tRNA synthetases
δ1 variant of SARS-COV-2 acquires spike V1176F and yields a highly mutated subvariant in Europe
SARS-COV-2 C.1.2 variant is highly mutated but may possess reduced affinity for ACE2 receptor
Comparative linkage mapping uncovers massive chromosomal inversions that suppress recombination between locally adapted fish populations
SARS-COV-2 γ variant acquires spike P681H or P681R for improved viral fitness
Profiling of Nascent Lariat Intermediates Reveals Key Genetic Determinants of the Timing of Human Co-transcriptional Splicing
Post-transcriptionally regulated genes are essential for pluripotent stem cell survival
Senataxin and RNase H2 act redundantly to suppress genome instability during class switch recombination
Preclinical Efficacy of IMM-BCP-01, a Highly Active Patient-Derived Anti-SARS-CoV-2 Antibody Cocktail
Explosive Synchronization-Based Brain Modulation Reduces Hypersensitivity in The Brain Network: A Computational Model Study
Protease-controlled secretion and display of intercellular signals
Inverse Potts model improves accuracy of phylogenetic profiling
Genomic identification, annotation, and comparative analysis of Vacuolar-type ATP synthase subunits in Diaphorina citri
High-throughput imaging of Caenorhabditis elegans aging using collective activity monitoring
Genome-wide association study of open fieldbehavior in outbred heterogeneous stock ratsidentifies multiple loci implicated inpsychiatric disorders
New adaptive peaks for crops - an example from improvement of drought-resilience of sorghum in Ethiopia
Nandrolone Decanoate supplementation promotes AMPK activation and divergent brain connectivity rearrangements in adult and aged mice.
Functional connectome of brainstem nuclei involved in autonomic, limbic, pain and sensory processing in living humans from 7 Tesla resting state fMRI
Ultrasound-mediated delivery of novel tau-specific monoclonal antibody enhances brain uptake but not therapeutic efficacy
High-throughput Evaluation of Epilepsy-associated KCNQ2 Variants Reveals Functional and Pharmacological Heterogeneity
Functional connectome of arousal and motor brainstem nuclei in living humans by 7 Tesla resting-state fMRI
Genetic architecture underlying variation in floral meristem termination in Aquilegia
Mitochondrial Haplogroup Association with Fasting Glucose Response in African Americans Treated with a Thiazide Diuretic
BioThings SDK: a toolkit for building high-performance data APIs in biomedical research
Spatial and temporal control of expression with light-gated LOV-LexA
High survival following bleaching highlights the resilience of a highly disturbed region of the Great Barrier Reef
Optimal Precision and Accuracy in 4Pi-STORM using Dynamic Spline PSF Models
Single-molecule analysis of the entire perfringolysin O poreformation pathway
Heptanol-mediated phase separation determines phase preference of molecules in live cell membranes
Simplifying MS1 and MS2 spectra to achieve lower mass error, more dynamic range, and higher peptide identification confidence on the Bruker timsTOF Pro
Adjusting for Common Variant Polygenic Scores Improves Yield in Rare Variant Association Analyses
Nuclear DNA-encoded fragments of mitochondrial DNA (mtDNA) confound analysis of selection of mtDNA mutations in human primordial germ cells.
Myogenetic oligodeoxynucleotides as anti-nucleolin aptamers inhibit the growth of embryonal rhabdomyosarcoma cells
Precision localization of cellular proteins with fluorescent Fab-based probes
Zapline-plus: a Zapline extension for automatic and adaptive removal of frequency-specific noise artifacts in M/EEG
Performance Scaling for Structural MRI Surface Parcellations: A Machine Learning Analysis in the ABCD Study
Chronic alcohol drinking persistently suppresses thalamostriatal excitation of cholinergic neurons to impair cognitive flexibility
Ochratoxin A induces behavioral and neurochemical changes in adult zebrafish
Molecular atlas of the human brain vasculature at the single-cell level
Structural network alterations in focal and generalized epilepsy follow axes of epilepsy risk gene expression: An ENIGMA study
Cryo-EM Structures of Amyloid-β 42 Filaments from Human Brain
MIR822 modulates monosporic female gametogenesis through an ARGONAUTE9-dependent pathway in Arabidopsis thaliana
Photosynthetic induction upon transfer from low to high light is affected by leaf nitrogen content in tomato
Preventing ovariectomy-induced weight gain decreases tumor burden in rodent models of obesity and postmenopausal breast cancer.
Identification of Significant Gene Expression Changes in Multiple Perturbation Experiments using Knockoffs
Inferring copy number variation from gene expression data: methods, comparisons, and applications to oncology
Does timing of birth affect juvenile and mare survival in wild plains zebra?
Novel genetic sex markers reveal unexpected lack of, and similar susceptibility to, sex reversal in free-living common toads in both natural and anthropogenic habitats
Mod3D: A Low-Cost, Flexible Modular System of Live-Cell Microscopy Chambers and Holders
Displacement of PKA catalytic subunit from AKAP signaling islands drives pathology in Cushing's syndrome
Metabolic Potential of Microbial Communities in the Hypersaline Sediments of the Bonneville Salt Flats
Human placental bed transcriptomic profiling reveals inflammatory activation of endothelial cells in preeclampsia
Characterization of red fluorescent reporters for dual-color in vivo three-photon microscopy
Microglia remodel the synaptic signaling required for context-dependent cognitive performance
Increased Functional Connectivity Characterises the Prodromal Phase of the Migraine Cycle
Acute silencing uncovers multiple forms of activity-dependent neuronal survival in the mature entorhinal cortex
Estimating null and potent modes of feedforward communication in a computational model of cortical activity
Environmental variability and longevity predict the speed of the acute glucocorticoid response across birds.
Trivial Excitation Energy Transfer to Carotenoids is an Unlikely Mechanism for Non-Photochemical Quenching in LHCII
The biomechanical context influences the output signaling, independently of PIK3CA mutations in breast cancer cells.
A method for independent estimation of false localisation rate for phosphoproteomics
Computational Modeling of Aerosol Particle Transport through Lung Mucosa
Multi-Functionalized Self-Bonding MXene for Minimal-invasive Jet-injected Neural Interface and Tissue Healing
Impact of walking speed and motion adaptation on optokinetic nystagmus-like head movements in the blowfly Calliphora
SSIM can robustly identify changes in 3D genome conformation maps
Demographic model and biological adaptation inferred from the genome-wide SNP data reveal tripartite origins of southernmost Chinese Huis
Putting pesticides on the map for pollinator research and conservation
Microbial community dispersal in sourdough
Mass-selective and ice-free cryo-EM protein sample preparation via native electrospray ion-beam deposition
In vivo single cell transcriptomics reveals Klebsiella pneumoniae rewiring of lung macrophages to promote infection
Coherent oscillations in balanced neural networks driven by endogenous fluctuations
All-viral tracing of monosynaptic inputs to single birthdate-defined neurons in the intact brain
Crystal or Jelly? Effect of Color on the Perception of Translucent Materials with Photographs of Real-world Objects
Systems-level analysis of transcriptome reorganization during liver regeneration
Indisulam synergizes with palbociclib to induce senescence through inhibition of CDK2 kinase activity
A longer stance is more stable for a standing horse
ImmunAL: a frame to identify the immunological markers for Mild Moderated Alzheimer's Disease applying Multiplex Network Model
nQMaker: estimating time non-reversible amino acid substitution models
GoMi - A new gold standard corpus for miRNA Named Entity Recognition to test dictionary, rule-based and machine-learning approaches.
FindZX: an automated pipeline for detecting and visualising sex chromosomes using whole-genome sequencing data
Analysis of vascular architecture and parenchymal damage generated by reduced blood perfusion in decellularized porcine kidneys using a gray level co-occurrence matrix
Detecting cell-of-origin and cancer-specific features of cell-free DNA with Nanopore sequencing
Gene losses in the common vampire bat illuminate molecular adaptations to blood feeding
Investigating the interaction between inter-locus and intra-locus sexual conflict using hemiclonal analysis in Drosophila melanogaster
Microbiota mediated plasticity promotes thermal adaptation in Nematostella vectensis
Increase in nutrient availability promotes success of invasive plants through increasing growth and decreasing anti-herbivory defenses
G-IRAE: a Generalised approach for linking the total Impact of invasion to species' Range, Abundance and per-unit Effects
Dynamic changes in spatial representation within the posterior parietal cortex in response to visuomotor adaptation
M1 dynamics share similar inputs for initiating and correcting movement
The protein-binding pocket of Botulinum neurotoxin B accommodates a preassembled synaptotagmin / ganglioside complex
BugSplit: highly accurate taxonomic binning of metagenomic assemblies enables genome-resolved metagenomics
Zebrafish larvae as a powerful model to dissect protective innate immunity in response to Legionella pneumophila infection
Structural and functional properties of a magnesium transporter of the SLC11/NRAMP family
EZTraits: a Programmable Tool to Evaluate Multi-site Deterministic Traits
Interplay between positive and negative regulation by B3-type transcription factors is critical for the accurate expression of the ABA INSENSITIVE 4 gene.
Systematic analysis of membrane contact sites in Saccharomyces cerevisiae uncovers modulators of cellular lipid distribution
ARGONAUTE proteins regulate a specific network of genes through KLF4 in mouse embryonic stem cells
Fast bacterial growth reduces antibiotic accumulation and efficacy
The genetic architecture of language functional connectivity
Remembering the pattern: A longitudinal case study on statistical learning in spatial navigation and memory consolidation
Relationships between the hard and soft dimensions of the nose in Pan troglodytes and Homo sapiens reveal the nasal protrusions of Plio-Pleistocene hominids
Plant growth and phytoactive alkaloid synthesis in Mitragyna speciosa (kratom) in response to varying radiance
Genetic Diversity of Bundibugyo Ebolavirus from Uganda and the Democratic Republic of Congo
Epicardial transplantation of autologous atrial appendage micrografts-evaluation of safety and feasibility in pigs after coronary artery occlusion
Metagenomic data for Halichondria panicea from Illumina and Nanopore sequencing and preliminary genome assemblies for the sponge and two microbial symbionts.
Self-renewing tissue-resident endothelial-macrophage progenitor cells originate from yolk sac and are a local source of inflammation and neovascularization in postnatal aorta
Linking photoacclimation responses and microbiome shifts between depth-segregated sibling species of reef corals
Treatment with IFB-088 improves neuropathy in CMT1A and CMT1B mice
Deficiency of p38α-MAPK in myeloid cells ameliorates symptoms and pathology of APP-transgenic Alzheimer's disease mice
Pathogen-derived mechanical cues regulate the spatio-temporal implementation of plant defense
Therapeutic KRASG12C inhibition drives effective interferon-mediated anti-tumour immunity in immunogenic lung cancers
Transcriptional variability accelerates pre-leukemia by cell diversification and perturbation of protein synthesis
Structural basis for activation and gating of IP3 receptors
Cryo-ET distinguishes platelets during pre-acute myeloid leukemia from steady state hematopoiesis
Experimental evolution of extremophile levels of radiation resistance in Escherichia coli
V-type H+ ATPase Activity is Required for Embryonic Dorsal-Ventral Symmetry Breaking
Degradation of ribosome and chaperone proteins is attenuated during the Differentiation of Replicatively Aged C2C12 Myoblasts
EFHD1 ablation reduces cardiac mitoflash activation and protects cardiomyocytes from ischemia.
Release of the ribosome biogenesis factor Bud23 from small subunit precursors in yeast
Rapid cell-free characterization of multi-subunit CRISPR effectors and transposons
Liposomal encapsulation of polysaccharides (LEPS) as an effective vaccine strategy to protect aged hosts against S. pneumoniae infection
Mapping Molecular Gene Signatures Among Respiratory Viruses Based on Large-Scale and Genome-wide Transcriptomics Analysis
Lactate Increases Stemness of CD8+ T Cells to Augment Anti-Tumor Immunity
Pathogen-derived 9-methyl sphingoid base is perceived by a lectin receptor kinase in Arabidopsis
Plant-based production of SARS-CoV-2 antigens for use in a subunit vaccine
Two distinct classes of co-chaperones compete for the EEVD motif in heat shock protein 70 (Hsp70) to tune its activity
Topological analysis of a bacterial DedA protein associated with alkaline tolerance and antimicrobial resistance.
Conserved chromatin and repetitive patterns reveal slow genome evolution in frogs
Behavioral phenotyping of Zip8 393T-KI mice for in vivo study of schizophrenia pathogenesis
Differential nuclear import sets the timing of protein access to the embryonic genome
Bees can be trained to identify SARS-CoV-2 infected samples.
A peroxide-responding sRNA evolved from a peroxidase mRNA
ASF1 activation PI3K/AKT pathway regulates sexual and asexual development in filamentous ascomycete
Widespread Utilization of Diverse Organophosphate Pollutants by Marine Bacteria
Circulatory neutrophils exhibit enhanced neutrophil extracellular trap formation in early puerperium: NETs at the nexus of thrombosis and immunity?
Outsourced hearing in spiders by using their webs as auditory sensors
Doors and corners of variance partitioning in statistical ecology
Strip1 regulates retinal ganglion cell survival by suppressing Jun-mediated apoptosis to promote retinal neural circuit formation
Rvb1/Rvb2 proteins couple transcription and translation during glucose starvation
The pathobiology of Mycobacterium abscessus revealed through phenogenomic analysis
Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14
Different brain systems support the aversive and appetitive sides of human pain-avoidance learning
Brain hubs defined in the group do not overlap with regions of high inter-individual variability
The power of peer networking for improving STEM faculty job applications: a successful pilot program
The intestinal circadian clock drives microbial rhythmicity to maintain gastrointestinal homeostasis
Colon Innervating TRPA1 Positive Nociceptors Influence Mucosal Health In Mice
PathoClock and PhysioClock in mice recapitulate human multimorbidity and heterogeneous aging
Nuclear PHGDH promotes neutrophil recruitment to drive liver cancer progression
A mathematical model for electrical activity in pig atrial tissue
Active reconfiguration of cytoplasmic lipid droplets governs migration of nutrient-limited phytoplankton
Identification of age-associated proteins and functional alterations in human primary retinal pigment epithelium cells
Transfer of Knowledge from Model Organisms to Evolutionarily Distant Non-Model Organisms: The Coral Pocillopora damicornis Membrane Signaling Receptome
Nanoscopic resolution within a single imaging frame
Calling the Amino Acid Sequence of a Protein/Peptide from the Nanospectrum Produced by a Sub-nanometer Diameter Pore
Physarum polycephalum: Establishing an Assay for Testing Decision-making Under Shifting Somatic Boundaries
Evaluation role of miR-124 in neurodegenerative diseases: literature review and in silico analysis
Adaptation of peristaltic pumps for laminar flow experiments
A fluorescence-based viability assay for Phytophthora agathidicida oospores
Aerosolization of Mycobacterium tuberculosis by tidal breathing
Boosting of SARS-CoV-2 immunity in nonhuman primates using an oral rhabdoviral vaccine
VISTA as a ligand downregulates LPS-mediated inflammation in macrophages and neutrophils
Extrasynaptic NMDA receptors bidirectionally modulate intrinsic excitability of inhibitory neurons
Neural dynamics of retrieval suppression in abolishing item-specific cortical pattern of unwanted emotional memories
A common neural currency account for social and non-social decisions
HEAT SHOCK FACTOR BINDING PROTEIN limits meiotic crossovers by repressing HEI10 transcription
Elevated islet prohormone ratios as indicators of insulin dependency in islet transplant recipients
Maintenance of ankle power and decreased inter-limb asymmetry during sprint running in fatigued multi-speed athletes
RTX-KG2: a system for building a semantically standardized knowledge graph for translational biomedicine
Improving MHC Class I antigen processing predictions using representation learning and cleavage site-specific kernels
SIMBA: SIngle-cell eMBedding Along with features
Mitoxantrone modulates a glycosaminoglycan-spike complex to inhibit SARS-CoV-2 infection
Source-sink connectivity: a novel resting-state EEG marker of the epileptogenic zone
Preparatory attention incorporates contextual expectations
The role of oxytocin in modulating self-other distinction brain: a pharmacological fMRI study
Alone Again: Altered Activation in the Observation Execution System during Synchronization in High Loneliness Individuals
A second view on the evolution of flight in stick and leaf insects (Phasmatodea)
The functional differences between paralogous regulators define the control of the General Stress Response in Sphingopyxis granuli TFA
Comparison of dipsogenic responses of adult offspring as a function of different perinatal programming models
How low can you go? Driving down the DNA input requirements for nanopore sequencing
Wild cereal grain consumption among Early Holocene foragers of the Balkans predates the arrival of agriculture
Neurexins Regulate GABA Co-release by Dopamine Neurons
Palmitoylation of PD-L1 Regulates Its Membrane Orientation and Immune Evasion
Repression of MAPK/Erk signaling by Efnb2-Ephb4-Rasa1 is required for lymphatic valve formation
Distinct phases within large RNP granules of C. elegans oocytes are associated with differential stress responses of RNA binding proteins
Comparative genomics of Xylella fastidiosa suggests determinants of host-specificity and expands its mobile genetic elements repertoire
MiR-339-3p aggravates rat vascular inflammation induced by AT1R autoantibodies by down-regulating BKα protein expression
The genome of the camphor tree and the genetic and climatic relevance of the top-geoherbalism in this medicinal plant
T7Max transcription system
Transcriptional Regulation of Synthetic Polymer Networks
The quantitative contribution of different Photosystem II compartments to non-photochemical quenching in Arabidopsis
Old and ancient trees are life history lottery winners and act as evolutionary buffers against long-term environmental change
A hierarchical transcriptional network activates specific CDK inhibitors that regulate G2 to control cell size and number in Arabidopsis
Repurposing Tranexamic Acid as an Anticancer Agent
The ASCC2 CUE domain contacts adjacent ubiquitins to recognize K63-linked polyubiquitin
Identifying common and novel cell types in single-cell RNA-sequencing data using FR-Match
Structure of the human ATM kinase and mechanism of Nbs1 binding
Loss of wings induces the expression of the worker-like phenotype in queens of a ponerine ant
Wild-type Caenorhabditis elegans Isolates Exhibit Distinct Gene Expression Profiles in Response to Microbial Infection
Hair phenotype diversity across Indriidae lemurs
Combining metabolomics and experimental evolution reveals key mechanisms underlying longevity differences in laboratory evolved Drosophila melanogaster populations
Tuberin levels during cellular differentiation in brain development
The ESX-1 secretion system senses bacterial contact and prepares mycobacteria for environmental adaptation
Insight in the quorum sensing-driven lifestyle of the non-pathogenic Agrobacterium tumefaciens 6N2 and the interactions with the yeast Meyerozyma guilliermondii
An optimized live bacterial delivery platform for the production and delivery of therapeutic nucleic acids and proteins
Type IV pilus shapes a "bubble-jet" pattern opposing spatial intermixing of two interacting bacterial populations
TRPV1-lineage somatosensory fibers communicate with taste neurons in the mouse parabrachial nucleus
Synaptotagmin-7 enhances phasic dopamine release
14-3-3ζ constrains insulin secretion in pancreatic β-cells by regulating mitochondrial function
RNA Helix Thermodynamics: The End Game
Supercharged Cellulases Show Reduced Non-Productive Binding, But Enhanced Activity, on Pretreated Lignocellulosic Biomass
Ab initio phasing macromolecular structures using electron-counted MicroED data
Identification of multi-omics molecular signature of acute radiation injury using nonhuman primate model
In situ architecture of the ciliary base reveals the stepwise assembly of IFT trains
Long-term evolution of antibiotic persistence in P. aeruginosa lung infections
Amoeboid-like neuronal migration ensures correct horizontal cell layer formation in the developing vertebrate retina
Automatic identification and annotation of MYB gene family members in plants
Spatial proteogenomics reveals distinct and evolutionarily-conserved hepatic macrophage niches
Adaptive coding of pain prediction error in the anterior insula
Formation of multinucleated globoid cells in Krabbe iPSC-derived microglia cultures: a preliminary investigation
Cellular perception of growth rate and the mechanistic origin of bacterial growth laws
PySOFI: an open source Python package for SOFI
Oxidative stress induces inflammation of lens cells and triggers immune surveillance of ocular tissues
Effects of dual deletion of glnR and mtrA on expression of nitrogen metabolism genes in Streptomyces venezuelae
Antibiotic resistance via bacterial cell shape-shifting
Ionizing radiation improves RIG-I mediated immunotherapy through enhanced p53 activation in malignant melanoma
Dynamic Functional Brain Reconfiguration During Sustained Pain
Long-term imaging of the ventral nerve cord in behaving adult Drosophila
Single-cell transcriptomics unveils xylem cell development and evolution
Blood flow synchronization in renal microcirculation - a high-resolution imaging study.
Pharmacological mechanisms on the anti-breast cancer property of Coix lacryma-jobi: A network-based analysis
iHypoxia: an integrative database of the expression dynamics of proteins in response to hypoxia in animals
Identification of binding interaction between Curcumin derivative and PERK13 Proline rich receptor like protein kinase protein using In silico docking techniques - to help plants tackle salt water
SPOT-1D-LM: Reaching Alignment-profile-based Accuracy in Predicting Protein Secondary and Tertiary Structural Properties without Alignment.
Kernel-based genetic association analysis for microbiome phenotypes identifies host genetic drivers of beta-diversity
Genomic insights into the population history and biological adaptation of Southwestern Chinese Hmong-Mien people
Escape from X-inactivation in twins exhibits intra- and inter-individual variability across tissues and is heritable
When are bacteria really gazelles? Comparing patchy ecologies with dimensionless numbers
Intermittent fasting induces rapid hepatocyte proliferation
Recurrent Independent Pseudogenization Events of the Sperm Fertilization Gene ZP3r in Apes and Monkeys
The nitrogen phosphotransferase regulator PtsN (EIIANtr) regulates inorganic polyphosphate production in Escherichia coli
Characterisation of the phase-variable autotransporter Lav reveals a role in host cell adherence and biofilm formation in Non-Typeable Haemophilus influenzae
A novel automated approach for improving standardization of the marble burying test enables quantification of burying bouts and activity characteristics
Propofol modulates functional connectivity signatures of sustained attention
Amyloid-beta and tau pathologies are both necessary to induce novel stage-specific microglia subtypes during Alzheimer's disease progression.
Dorsolateral prefrontal cortex supports speech perception in listeners with cochlear implants
Genome scale modeling of the protein secretory pathway reveals novel targets for improved recombinant protein production in yeast
Sex Differences in Pubertal Circadian and Ultradian Rhythmic Development Under Naturalistic Conditions
A plasma membrane-localized polycystin-1/polycystin-2 complex in endothelial cells elicits vasodilation
Cyperus rotundus root extract inhibits progress of lymphedema in mouse tail model
Interactive 3D visualization and post-processing analysis of vertex-based unstructured polyhedral meshes with ParaView
Identification of electroporation sites in the complex lipid organization of the plasma membrane
Nanopore microscope identifies RNA isoforms with structural colors
Airpart: Interpretable statistical models for analyzing allelic imbalance in single-cell datasets
Immunogenic potential of neopeptides depends on parent protein subcellular location
scTriangulate: Decision-level integration of multimodal single-cell data
Mapping enzyme catalysis with metabolomic biosensing
Multiplexed ultrasound imaging using clustered gas vesicles and spectral imaging
In vivo adenine base editing corrects newborn murine model of Hurler syndrome
Population-specific patterns of toxin sequestration in monarch butterflies from around the world
Evolutionary epidemiology of a zoonosis
Estimating the maximal growth rates of eukaryotic microbes from cultures and metagenomes via codon usage patterns
Anti-TRAP/SSP2 monoclonal antibodies can inhibit sporozoite infection and enhance protection of anti-CSP monoclonal antibodies
The Respiratory Resistance Sensitivity Task: An Automated Method for Quantifying Respiratory Interoception and Metacognition
A Kernel-based Nonlinear Manifold Learning for EEG Channel Selection with Application to Alzheimer's Disease
Bilaterally Reduced Rolandic Beta Band Activity in Minor Stroke Patients
Intratumoral and extratumoral synapses are required for glioblastoma progression in Drosophila
Behavioral and molecular underpinnings of performance variability in eyeblink conditioning in male and female mice
Individual differences in visual search performance extend from artificial arrays to naturalistic environments.
Cholinergic modulation of distinct inhibitory domains in granule cells of the olfactory bulb
Cortical Spheroid Model for Studying the Effects of Ischemic Brain Injury
Association of ocean macroplastic debris with stranded sea turtles in the Central Gulf of Thailand
Diet-induced obese mice are resistant to improvements in cardiac function resulting from short-term adropin treatment
Molecular and functional characterization of the mouse intracardiac nervous system
Propionate ameliorates diabetes-induced neurological dysfunction through regulating the PI3K-AKT-eNOS signaling pathway
Reproducible, high-dimensional imaging in archival human tissue by Multiplexed Ion Beam Imaging by Time-of-Flight (MIBI-TOF)
Polypolish: short-read polishing of long-read bacterial genome assemblies
Using a Homeogram to Detect Sleep in Free-living Animals
Thermal boldness: Volunteer exploration of extreme temperatures in Drosophila melanogaster
Assessing species coverage and assembly quality of rapidly accumulating sequenced genomes
Admixture dynamics in colonial Mexico and the genetic legacy of the Manila Galleon
Into the range: a latitudinal gradient or a center-margins differentiation of ecological strategies in Arabidopsis thaliana?
Stratification in Microbial Communities with Depth and Redox Status in a Eutrophic Lake Across Two Years
Intrinsic maturation of sleep output neurons regulates sleep ontogeny in Drosophila
Astrocytic urea cycle detoxifies Aβ-derived ammonia while impairing memory in Alzheimers Disease
Tiam1-mediated synaptic plasticity drives comorbid depressive symptoms in chronic pain
Single-cell Networks Reorganise to Facilitate Whole-brain Supercritical Dynamics During Epileptic Seizures
A network information theoretic framework to characterise muscle synergies in space and time
Endogenous recruitment of frontal-sensory circuits during visual discrimination
Enhanced mismatch negativity responses in harmonic compared to inharmonic sound sequences
Brain functional connectome defines a transdiagnostic dimension associated with cognition and psychopathology in youth
Three-dimensional reconstruction of the face and feeding apparatus of the predatory nematode Pristionchus pacificus
A video-based behavioural intervention associated with improved HPV knowledge and intention to vaccinate
Connexin Hemichannels with Prostaglandin Release in Anabolic Function of Bone to Mechanical Loading
Alpha cell dysfunction in early type 1 diabetes
SEX DIFFERENCES IN BLOOD PRESSURE RESPONSE TO CONTINUOUS ANG II INFUSION: ARE ONLY SEX HORMONES TO BLAME?
Network-based analysis on the pharmacological mechanisms underlying the anti-diabetic property of Coix lachryma-jobi
Generative modeling of histology tissue reduces human annotation effort for segmentation model development.
PDXNet Portal: Patient-Derived Xenograft model, data, workflow, and tool discovery
The Pathogenic R5L Mutation Disrupts Formation of Tau Complexes on the Microtubule by Altering Local N-Terminal Structure
findPC: An R package to automatically select number of principal components in single-cell analysis
Determining salmon provenance with automated otolith reading
Attention please: modeling global and local context in glycan structure-function relationships
Diet and Domestication Drive Evolution of the Gut Holobiome
SURFMAP: a software for mapping in two dimensions protein surface features
Remarkable Adsorption Performance of Rutile TiO2 (110) Nanosheet for DNA Nucleobases: A First-Principles Study
Sex differences in parental response to offspring begging are associated with pair bond strength across birds
Distinct and common features of numerical and structural chromosomal instability across different cancer types
A Genomic Perspective on the Evolutionary Diversification of Turtles
Effects of early and late life environments on ageing
Genomic and common garden approaches yield complementary results for quantifying environmental drivers of local adaptation in rubber rabbitbrush, a foundational Great Basin shrub
City climate and landscape structure shape pollinators, nectar and transported pollen along a gradient of urbanization
Synchronous seasonality in the gut microbiota of wild wood mouse populations
Competition for water and species coexistence in phenologically structured annual plant communities
Accounting for animal movement improves vaccination strategies against wildlife disease in heterogeneous landscapes
The biological sink of atmospheric H2 is more sensitive to spatial variation of microbial diversity than N2O and CO2 emissions in an agroecosystem
Separating neural oscillations from aperiodic 1/f activity: challenges and recommendations
Decoding of cortex-wide brain activity from local recordings of neural potentials
Dysfunctional temporal stages of eye-gaze perception in adults with ADHD: a high-density EEG study
Unifying turbulent dynamics framework distinguishes different brain states
Spatial signatures of anesthesia-induced burst-suppression differ between primates and rodents
An Optimal Policy Model for Concurrent Uncertainty Estimation During Decision Making
Assessing HD-EEG functional connectivity states using ahuman brain computational model
Retroactive analysis of single cell transcriptome profiles using next-generation algorithms revised the identification of several resilient retinal ganglion cell types
Post-injury born oligodendrocytes integrate into the glial scar and inhibit growth of regenerating axons by premature myelination
Stimulus-dependent orientation strategies in monarch butterflies
Relapse to cotinine seeking in rats: Differential effects of sex
Fetal programming by sodium saccharin and damage on male offspring reproductive
Identifying tumor cells at the single cell level
Turning high-throughput structural biology into predictive inhibitor design
Simulation atomic force microscopy to predict correlated conformational dynamics in proteins from topographic imaging
Single-Shot Optical Projection tomography for high-speed volumetric imaging
Maf is a regulator of differentiation for gut immune epithelial cell Microfold cell (M cell)
Single cell profiling of the Timp gene family
Hepatocyte Cell Cycle Progression Depends on a Transcriptional Repressor Cascade Downstream of Wnt Signaling
Targeted Tshz3 deletion in corticostriatal circuit components segregates core autistic behaviors
Reward timing matters in motor learning
A Golden Gate-based Plasmid Library for the Rapid Assembly of Biotin Ligase Constructs for Proximity Labelling
Effect of different ambient temperatures on reproductive outcome and wellbeing of lactating females in two mouse strains
Open-Source Low-Cost Cardiac Optical Mapping System
Food or physics: plankton communities structured across Gulf of Alaska eddies
A New Mouse Model of Diffuse Midline Glioma to Test Targeted Immunotherapies
Evaluation of Deep Neural Network ProSPr for Accurate Protein Distance Predictions on CASP14 Targets
A Hydrogel Microneedle-assisted Assay Integrating Aptamer Probes and Fluorescence Detection for Reagentless Biomarker Quantification
A Novel 3D Co-culture Platform for Integrating Tissue Interfaces for Tumor Growth, Migration and Therapeutic Sensitivity: PP-3D-S
Ubiquitin E3 ligases Atrogin-1 and MuRF1 protein contents are differentially regulated in the rapamycin-sensitive mTOR-S6K1 signaling pathway in C2C12 myotubes
Microtubule disassembly by caspases is the rate-limiting step of cell extrusion
Cofilin regulates actin network homeostasis and microvilli length in mouse oocytes
Interferon-gamma Induces Melanogenesis Via Post-Translational Modification of Tyrosinase
Human 5p-tailed Mirtrons are Processed by RNaseP
Human enteric viruses shape disease phenotype through divergent innate immunomodulation
Sustained Ranavirus outbreak causes mass-mortality and morbidity in imperiled amphibians.
Phosphatases are predicted to govern prolactin-mediated JAK-STAT signaling in pancreatic beta cells
DAF-2/insulin IGF-1 receptor regulates mobility during ageing by integrating opposite inputs from muscle and neuronal tissues
Discovery of small molecule inhibitors of the PTK7/β-catenin interaction targeting the Wnt signaling pathway in colorectal cancer
Interferon-Gamma Signaling Promotes Melanoma Progression and Metastasis
KRAS is vulnerable to reversible switch-II pocket engagement in cells
Integrated analysis of single-cell and transcriptome based RNA-seq multilayer network and WGCNA for construction and validation of an immune cell-related prognostic model in clear cell renal cell carcinoma
Ultraviolet radiation modulates DNA methylation in melanocytes
Chemophoresis Engine: Universal Principle of ATPase-driven Cargo Transport
Speed fluctuations of bacterial replisomes
Diversity and evolution of nitric oxide reduction
Genetic and environmental influences on the evolution of virulence in the HIV-associated opportunistic human fungal pathogen Cryptococcus neoformans
Extremely reduced supergroup F Wolbachia: transition to obligate insect symbionts
Golgi structural defect impairs glycosaminoglycan synthesis, sulfation, and secretion
Heat shock chaperone HSPB1 regulates cytoplasmic TDP-43 phase separation and liquid-to-gel transition
Clustered PHD domains in mixed lineage leukaemia proteins are attracted by acetylation-rich active promoters and enhancers
Characterization of pyridomycin B reveals the formation of functional groups in antimycobacterial pyridomycin
Hunting the plant surrender signal activating apoplexy in grapevines after Neofusicoccum parvum infection
Mitochondrial phenotypes in purified human immune cell subtypes and cell mixtures
Bacterial, phytoplankton, and viral dynamics of meromictic Lake Cadagno offer insights into the Proterozoic ocean microbial loop
Annulment of antagonism shifts properties that are beneficial to plants in two-member consortia of Bacillus velezensis
Impact of IgG isotype on the induction of antibody-dependent cellular phagocytosis of HIV by human milk leukocytes
On the brain networks organization of individuals with high versus average fluid intelligence: a combined DTI and MEG study
Predicting the Influence of Axon Myelination on Sound Localization Precision Using a Spiking Neural Network Model of Auditory Brainstem
Super-doses of dietary vitamin D3 intake in aged laying hens illustrates limitation of 24,25-dihydroxycholecalciferol conversion
Mutual Regulation between PFKP and VEGF Promotes Glioblastoma Tumor Growth
Dysregulated Protein Translation Control in Hidradenitis Suppurativa: Implication for Lesion-associated Squamous Cell Carcinoma Development
Shared and distinct genetic features in human and canine B-cell lymphomas
Characterization of Cell-cell Communication in Autistic Brains with Single Cell Transcriptomes
Identification of antineoplastic agents for oral squamous cell carcinoma: an integrated bioinformatics approach using differential gene expression and network biology
In vivo mRNA delivery to virus-specific T cells by light-induced ligand exchange of MHC class I antigen-presenting nanoparticles
The β-amylase7 gene in Zea mays encodes a protein with structural and catalytic properties similar to Arabidopsis BAM2
scSPLAT, a scalable plate-based protocol for single cell WGBS library preparation
Coral niche construction: coral recruitment increases along a coral-built structural complexity gradient
Shell shape as an indicator of phenotypic stocks of Tehuelche scallop (Aequipecten tehuelchus) in Northern Patagonia, Argentina
Endothelial Cell-Specific Molecule-1 Inhibits Albuminuria in Diabetic Mice
Short-term plasticity in the visual thalamus
Functional and structural features of L2/3 pyramidal cells continuously covary with pial depth in mouse visual cortex
Stable modulation of neuronal oscillations produced through brain-machine equilibrium
Visual space curves before eye movements
Sex Differences in Cortical Morphometry during Ageing: Examining the Interplay between Lifestyle and Reproductive Factors
Glucose uptake in mammalian cells measured by ICP-MS
A live yeast supplementation to gestating ewes improves bioactive molecules composition in colostrum with no impact on its bacterial composition and beneficially affects immune status of the offspring
Integrating Subclonal Response Heterogeneity to Define Cancer Organoid Therapeutic Sensitivity
γδ T cells are effectors of immune checkpoint blockade in mismatch repair-deficient colon cancers with antigen presentation defects
MspA Porin as a Local Nanopore Probe for Membrane-bound Proteins
The chromatin regulator HMGA1a undergoes phase separation in the nucleus
Labkit: Labeling and Segmentation Toolkit for Big Image Data
Methods for analyzing continuous conformational variability of biomolecules in cryo electron subtomograms: HEMNMA-3D vs. traditional classification
Interpretable Pairwise Distillations for Generative Protein Sequence Models
The 4D Nucleome Data Portal: a resource for searching and visualizing curated nucleomics data
Transcriptomic responses of Galapagos finches to avian pox virus infection
Genome sequencing and comparative analysis of Ficus benghalensis and Ficus religiosa trees reveal evolutionary mechanisms of longevity
Functional screen of Inflammatory Bowel Disease genes reveals key epithelial functions
Quantifying the scale of genetic diversity extinction in the Anthropocene
Oxalic acid binds to gustatory receptor Gr23a and inhibits feeding in the brown planthopper
Lin28a rejuvenates muscle stem cells via mitochondrial optimization
The PRO model accounts for the anterior cingulate cortex role in risky decision-making and monitoring
EEG-based clusters differentiate psychological distress, sleep quality and cognitive function in adolescents
ERα-LBD, a novel isoform of estrogen receptor alpha, promotes breast cancer proliferation and endocrine resistance
Structural rearrangement of the intracellular gate of the serotonin transporter induced by Thr276 phosphorylation
PSEA: A phenotypic similarity ensemble approach for prioritizes candidate genes to aid mendelian disease diagnosis
Pneumonia Detection with Semantic Similarity Scores
Enhanced metanephric specification to functional proximal tubule enables toxicity screening and infectious disease modelling in kidney organoids
OAC-39 is an O-acyltransferase required for the synthesis of maradolipids in the dauer larva of C. elegans
Genetic map of regional sulcal morphology in the human brain
Micro-aggregation of a pristine grassland soil selects for bacterial and fungal communities and changes in nitrogen cycling potentials
TRAKR - A reservoir-based tool for fast and accurate classification of neural time-series patterns
The cyanotoxin 2,4-DAB enhances mortality and causes behavioral and molecular dysfunctions associated with neurodegeneration in larval zebrafish
Composite receptive fields in the mouse auditory cortex
Repetition-attenuation of auditory N1 is modulated by the phonological representations of spoken word-forms
The secreted neuronal signal Spock1 regulates the blood-brain barrier
Motor Learning Drives Dynamic Patterns of Intermittent Myelination onBehaviorally-Activated Axons
A linear programming-based strategy to save pipette tips in automated DNA assembly
Rilmenidine mimics caloric restriction via the nischarin I1-imidazoline receptor to extend lifespan in C. elegans
Single-cell analysis of hepatoblastoma identifies distinct tumor cell signatures that predict susceptibility to chemotherapy using patient-specific tumor spheroids
Gaussian curvature dilutes the nuclear lamina, favoring nuclear rupture, especially at high strain rate
Respiratory syncytial virus matrix protein assembles as a lattice with local and extended order that coordinates the position of the fusion glycoprotein
A High-Resolution Method for the Systematic Detection of EMS-Induced Mutations in a Sequenced Population
Efficient incorporation and template-dependent polymerase inhibition are major determinants for the broad-spectrum antiviral activity of remdesivir
Development and Application of Multidimensional Lipid Libraries to Investigate Lipidomic Dysregulation Related to Smoke Inhalation Injury Severity
Whole genome sequences of Treponema pallidum subsp. endemicum isolated from Cuban patients: the non-clonal character of isolates suggests a persistent human infection rather than a single outbreak
Nucleocapsid mutations in SARS-CoV-2 augment replication and pathogenesis.
Opsonization by non-neutralizing antibodies can confer protection to SARS-CoV-2 despite Spike-dependent modulation of phagocytosis
A quantitative model of sporadic axonal degeneration in the Drosophila visual system
Evaluation of the Therapeutic Potential of Oral Phycocyanin-Rich Spirulina Extract in Neuropsychiatric Disorders.
Parkinsonian gait effects with DBS are associated with pallido-peduncular axis activation
Dual polarity voltage imaging reveals subthreshold dynamics and concurrent spiking patterns of multiple neuron-types
The Development of Sleep/Wake Disruption and Cataplexy as Hypocretin/Orexin Neurons Degenerate in Male vs. Female Orexin/tTA; TetO-DTA Mice
Deep learning based on stacked sparse autoencoder applied to viral genome classification of SARS-CoV-2 virus
Palaeogenomics reveal a hybrid origin of the world's largest Camelus species
CAR modulates plasma membrane nano-organization and immune signaling downstream of RALF1-FERONIA ligand-receptor signaling system
Organizing memories for generalization in complementary learning systems
Modular Derivation and Unbiased Single-cell Analysis of Regional Human Hindbrain And Spinal Neurons Enables Discovery of Nuanced Transcriptomic Patterns along Developmental Axes
A more complex basal complex: novel components mapped to the Toxoplasma gondii cytokinesis machinery portray an expanded hierarchy of its assembly and function
PRMT5 in T cells drives Th17 responses, mixed granulocytic inflammation and severe allergic airway inflammation
BBX proteins promote HY5-mediated UVR8 signaling in Arabidopsis
Ionic strength modulates HU protein-induced DNA supercoiling
ATP and Substrate Binding Regulates Conformational Changes of Human Peroxisomal ABC Transporter ALDP
An archaeal histone-like protein regulates gene expression in response to salt stress
Evolutionarily conserved clusters of colon with lung cancer susceptibility loci, linked with most DUSP phosphatase genes, may help to dissect mechanisms of cancer susceptibility
Phylogenetic profiling and cellular analyses of ARL16 reveal roles in traffic of IFT140 and INPP5E
Recurrent Duplication and Diversification of Acrosomal Fertilization Proteins in Abalone
Inhibiting ACSL1 related ferroptosis restrains MHV-A59 infection
In situ Alphavirus Assembly and Budding Mechanism Revealed by Cellular CryoET
Emergence of networks of shared restriction-modification systems in phage-bacteria ecosystems
Actin dynamics regulation by TTC7A/PI4KIIIα axis limits DNA damage and cell death during leukocyte migration
LKB1 signalling in dendritic cells controls whole-body metabolic homeostasis by limiting T helper 17 priming
Conjugation-based genome engineering in Deinococcus radiodurans
Nonadditive gene expression is correlated with nonadditive phenotypic expression in interspecific triploid hybrids of willow (Salix spp.)
A KARRIKIN INSENSITIVE2 paralog in lettuce mediates highly sensitive germination responses to karrikinolide
Regulation of Liver Regeneration by hepatocyte O-GlcNAcylation in mice
A functional SNP regulates E-cadherin expression by dynamically remodeling the 3D structure of a promoter-associated non-coding RNA transcript
Cross-seeding Controls Aβ Fibril Populations and Resulting Function
Local and global crosstalk among heterochromatin marks drives epigenome patterning in Arabidopsis
A Rapid Bead-Based Assay For Screening Of SARS-CoV-2 Neutralising Antibodies
A Novel Mice Model of Catecholaminergic Polymorphic Ventricular Tachycardia Generated by CRISPR/Cas9
Nicotinamide riboside kinase-2 inhibits JNK pathway and limits dilated cardiomyopathy in mice with chronic pressure overload
Structure-based Design of CDC42 Effector Interaction Inhibitors For the Treatment of Cancer
Gasotransmitter H2S accelerates seed germination via activating AOX mediated cyanide-resistant respiration pathway
The Endocytic Recycling Compartment Serves as a Viral Factory for Hepatitis E Virus
The CRP-like transcriptional regulator MrpC curbs c-di-GMP and 3,3 cGAMP nucleotide levels during development in Myxococcus xanthus
Accumulation of lncRNAs/DNA hybrid reveals RNase HII transcripts down-regulation in psoriasis.
Alkyne modified purines for assessing activation of Plasmodium vivax hypnozoites and growth of pre-erythrocytic and erythrocytic stages in Plasmodium spp.
Feature distribution learning by passive exposure
Impact of Variability in Cell Cycle Periodicity on Cell Population Dynamics
YeastMate: Neural network-assisted segmentation of mating and budding events in S. cerevisiae
Debunking the "junk": Unraveling the role of lncRNA-miRNA-mRNA networks in fetal hemoglobin regulation
Protein degradation analysis by affinity microfluidics
Injury-induced inflammatory signaling and hematopoiesis in Drosophila
Cnidarian hair cell development illuminates an ancient role for the class IV POU transcription factor in defining mechanoreceptor identity
The Legionella Lqs-LvbR regulatory network controls temperature-dependent growth onset and bacterial cell density
Respiratory and diarrhoeal pathogens in Malawian children hospitalized with diarrhoea and association with short-term growth
Vaccine-induced, high magnitude HIV Env-specific antibodies with Fc-mediated effector functions are insufficient to protect infant rhesus macaques against oral SHIV infection
Tagging active neurons by soma-targeted Cal-Light
In vivo imaging of the GnRH pulse generator reveals a temporal order of neuronal activation and synchronization during each pulse
SWI/SNF chromatin remodeler complex within the reward pathway is required for behavioral adaptations to stress
Differential and synergistic effects of low birth weight and Western diet on skeletal muscle vasculature, mitochondrial lipid metabolism and insulin signaling in male guinea pigs
SunCatcher: Clonal Barcoding with qPCR-Based Detection Enables Functional Analysis of Live Cells and Generation of Custom Combinations of Cells for Research and Discovery
Dynamic Instability of Dendrite Tips Generates the Highly Branched Morphologies of Sensory Neurons
ConTreeDP: A consensus method of tumor trees based on maximum directed partition support problem
ONTdeCIPHER: An amplicon-based nanopore sequencing pipeline for tracking pathogen variants
Functional single cell proteomic profiling of cells with abnormal DNA damage response dynamics
Detecting Cd adaptation footprint in C. riparius with a multi-genomic approach
Connecting neuromodulation, brain development, and life history timing associated with ecological speciation in Rhagoletis pomonella
Calcium-independent but voltage-dependent secretion (CiVDS) mediates synaptic transmission in a mammalian central synapse
Weak representation of awake/sleep states by local field potentials in aged mice
Functional connectivity networks of common synaptic inputs to motor neurons reveal neural spinal synergies during a multi-joint task
Neuronal hemoglobin induces α-synuclein cleavage and loss of dopaminergic neurons
Inhibition of TRPV4 rescues circuit and social deficits unmasked by acute inflammatory response in a Shank3 mouse model of Autism
The photobiology of the human circadian clock
Terminal selectors organize postmitotic chromatin accessibility for acquisition of serotonergic identity
Time-tagged ticker tapes for intracellular recordings
ALLOPURINOL BLOCKS THE FORMATION AND PROGRESSION OF AORTIC ANEURYSM IN A MOUSE MODEL OF MARFAN SYNDROME ACTING AS SCAVENGER OF REACTIVE OXYGEN SPECIES
Disentangling choice value and choice conflict in sequential decisions under risk
Transcriptomic analysis revealed reactive oxygen species scavenging mechanisms associated with ferrous iron toxicity in aromatic Keteki Joha rice
A monoclonal antibody that neutralizes SARS-CoV-2 variants, SARS-CoV, and other sarbecoviruses
An atlas of white matter anatomy, its variability, and reproducibility based on Constrained Spherical Deconvolution of diffusion MRI
Pleiotropic and Non-redundant Effects of an Auxin Importer in Setaria and Maize
Variable inhibition of unwinding rates of DNA catalyzed by the SARS-Cov-2 (COV19) helicase nsp13 by structurally distinct single DNA lesions.
Increased mTOR signaling, impaired autophagic flux and cell-to-cell viral transmission are hallmarks of SARS-CoV-2 infection.
The adenosine analogue prodrug ATV006 is orally bioavailable and has potent preclinical efficacy against SARS-CoV-2 and its variants
Public T-cell epitopes shared among SARS-CoV-2 variants are presented on prevalent HLA class I alleles
Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry
Constitutive nuclear accumulation of endogenous alpha-synuclein in mice causes motor dysfunction and cortical atrophy, independent of protein aggregation.
Cue-specific remodeling of the neuronal transcriptome through intron retention programs
Polymer-Assisted Condensation: A Mechanism for Hetero-Chromatin Formation and Epigenetic Memory
Direct induction of human neurons from fibroblasts carrying the neuropsychiatric 22q11.2 microdeletion reveals transcriptome- and epigenome-wide alterations
pVHL regulates protein stability of TCF/LEF transcription factor family via ubiquitin-independent proteasomal degradation
Novelty and uncertainty interact to regulate the balance between exploration and exploitation in the human brain.
Improving the robustness of engineered bacteria to nutrient stress using programmed proteolysis
Kdm6b confers Tfdp1 with the competence to activate p53 signalling in regulating palatogenesis
Single-cell chromatin and gene-regulatory dynamics of mouse nephron progenitors
Nuclear morphogenesis: forming a heterogeneous nucleus during embryogenesis
Optogenetic control of the Bicoid morphogen reveals fast and slow modes of gap gene regulation
In vivo mitochondrial matrix proteome profiling reveals RTN4IP1/OPA10 as an antioxidant NADPH oxidoreductase
COLD ATMOSPHERIC PLASMA DIFFERENTIALLY AFFECTS CELL RENEWAL AND DIFFERENTIATION OF STEM CELLS AND APC-DEFICIENT-DERIVED TUMOR CELLS IN INTESTINAL ORGANOIDS
The HIV latency reversal agent HODHBt enhances NK Cell effector and memory-like functions by increasing IL-15 mediated-STAT activation
Angiomotin isoform 2 promotes binding of PALS1 to KIF13B at the base of primary cilia and suppresses ciliary elongation
A mechanism for exocyst-mediated tethering via Arf6 and PIP5K1C driven phosphoinositide conversion
The crystal structure of vaccinia virus protein E2 and perspectives on the prediction of novel viral protein folds
The Hair Cell Analysis Toolbox: A machine learning-based whole cochlea analysis pipeline
Making Genomic Surveillance Deliver: A Lineage Classification and Nomenclature System to Inform Rabies Virus Elimination
DDX17 is required for efficient DSB repair at DNA:RNA hybrid deficient loci
Benchmarking imputation methods for network inference using a novel method of synthetic scRNA-seq data generation
Modular, robust and extendible multicellular circuit design in yeast
Prion-like α-synuclein pathology in the brains of infants: Krabbe disease as a novel seed-competent α-synucleinopathy
A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells.
The role of cell geometry and cell-cell communication in gradient sensing
DeepImageTranslator V2: analysis of multimodal medical images using semantic segmentation maps generated through deep learning
FAIRly big: A framework for computationally reproducible processing of large-scale data
Eoulsan 2: an efficient workflow manager for reproducible bulk, long-read and single-cell transcriptomics analyses
netCRS: Network-based comorbidity risk score for prediction of myocardial infarction using biobank-scaled PheWAS data
gcFront: a tool for determining a Pareto front of growth-coupled cell factory designs
A weighted constraint satisfaction approach to human goal-directed decision making
Specificity of California mouse pup vocalizations in response to olfactory cues
From compartments to gene loops: Functions of the 3D genome in the human brain
New cycle, same old mistakes? Overlapping vs. discrete generations in long-term recurrent selection
A multifaceted ecological assessment reveals the invasion of the freshwater red macroalga Montagnia macrospora (Batrachospermales, Rhodophyta) in Taiwan
A Proposed Unified Mitotic Chromosome Architecture
Aperiodic EEG activity masks the dynamics of neural oscillations during loss of consciousness from propofol
A multi-dataset evaluation of frame censoring for task-based fMRI
PyMVPD: A toolbox for multivariate pattern dependence
Deep learning models of cognitive processes constrained by human brain connectomes
Microscopic Quantification of Oxygen Consumption across Cortical Layers
Creatine transporter deficient rat show motor dysfunction linked with cerebellar alterations and muscle creatine deficiency without muscle atrophy
Impact of baseline culture conditions of mouse-derived cancer organoids when determining therapeutic response and tumor heterogeneity
Investigating the Role of Chromatin Remodeler FOXA1 in Ferroptotic Cell Death
RNA-seq, bioinformatic identification of potential MicroRNA-Like Small RNAs in the edible mushroom Agaricus bisporus and experimental approach for their validation
PoSTcode: Probabilistic image-based spatial transcriptomics decoder
Honey bees can store and retrieve independent memory traces after complex experiences that combine appetitive and aversive associations
Top-down predictions of visual features dynamically reverse their bottom-up processing in the occipito-ventral pathway to facilitate stimulus disambiguation and behavior
Screening of CHO-K1 endogenous promoters for expressing recombinant proteins in mammalian cell cultures
Diversity of reptile sex chromosome evolution revealed by cytogenetic and linked-read sequencing
Phylogenomic analyses in the apple genus Malus s.l. reveal widespread hybridization and allopolyploidy driving the diversifications, with insights into the complex biogeographic history in the Northern Hemisphere
Chasing the fitness optimum: temporal variation in the genetic and environmental expression of life-history traits for a perennial plant
Quantitative parameters of bacterial RNA polymerase open-complex formation, stabilization and disruption on a consensus promoter
The R346K Mutation in the Mu Variant of SARS-CoV-2 Alter the Interactions with Monoclonal Antibodies from Class 2: A Free Energy of Perturbation Study
scINSIGHT for interpreting single-cell gene expression from biologically heterogeneous data
Epigenetic clock and methylation studies in gray short-tailed opossums
Local and global chemical shaping of bacterial communities by redox potential
Early life stress-induced vulnerability to postpartum mental disturbance: prolonged dysregulation of the HPA axis and behavior
3D Structure Determination of Protein Complexes using Matrix-Landing Mass Spectrometry
Co-cultivation is a powerful approach to produce a robust functionally designed synthetic consortium as a live biotherapeutic product (LBP)
Obesity influences composition of salivary and fecal microbiota and impacts the interactions between bacterial taxa
Flow Cytometric Evaluation of Yeast-Bacterial Cell-Cell Interactions
Replication Fork Uncoupling Causes Nascent Strand Degradation and Fork Reversal
Ribosomal protein S1 plays a critical role in horizontal gene transfer by mediating the expression of foreign mRNAs
Truncation of poly-N-acetylglucosamine (PNAG) polymerization with N-acetylglucosamine analogues
Characterisation of a highly diverged mitochondrial ATP synthase peripheral stalk subunit b in Trypanosoma brucei
Single-cell transcriptomics reveals expression profiles of Trypanosoma brucei sexual stages
The Nup2 meiotic-autonomous region relieves autoinhibition of Nup60 to promote progression of meiosis and sporulation in Saccharomyces cerevisiae
Archaeal origins of gamete fusion
Differentiation of mouse embryonic stem cells into cells with spermatogonia-like morphology with chemical intervention-dependent increased gene expression of LIM homeobox 1 (Lhx1).
A pseudorabies virus serine/threonine kinase, US3, promotes retrograde transport in axons via Akt/mToRC1
Taxonomic classification methods reveal a new subgenus in the paramyxovirus subfamily Orthoparamyxovirinae
Guanosine-specific single-stranded ribonuclease effectors of a phytopathogenic fungus potentiate host immune responses
Mitochondrial active Ras2 protein promotes apoptosis and regulated cell death in a cAMP/PKA pathway-dependent manner in budding yeast.
A Novel Propidium Monoazide-Based PCR Assay Can Measure Viable Uropathogenic E. coli in Vitro and in Vivo
The cnf1 gene is associated to an expanding Escherichia coli ST131 H30Rx/C2 sublineage and confers a competitive advantage for host colonization
Transkingdom Analysis of the Female Reproductive Tract Reveals Bacteriophages Form Communities
Development of a metatranscriptomic analysis method for multiple intestinal sites and its application to the common marmoset intestine
Vht hydrogenase is required for hydrogen cycling during nitrogen fixation by the non-hydrogenotrophic methanogen Methanosarcina acetivorans.
Rates of primary production in groundwater rival those in oligotrophic marine systems
SARS-CoV-2 spike protein induces abnormal inflammatory blood clots neutralized by fibrin immunotherapy
Low antigen abundance limits efficient T-cell recognition of highly conserved regions of SARS-CoV-2
AUG-3387, a Human-Derived Monoclonal Antibody Neutralizes SARS-CoV-2 Variants and Reduces Viral Load from Therapeutic Treatment of Hamsters In Vivo
A dual endosymbiosis drives nutritional adaptation to hematophagy in the invasive tick Hyalomma marginatum
Modeling homing suppression gene drive in haplodiploid organisms
Codiversification of gut microbiota with humans
Frugivore gut passage increases seed germination: an updated meta-analysis
An arsenic stress signaling code in yeast
A SARS-CoV-2 variant elicits an antibody response with a shifted immunodominance hierarchy
Brain endothelial antigen presentation detains CD8+ T cells at the blood-brain barrier leading to its breakdown
Dynamic remodeling of ribosomes and endoplasmic reticulum in axon terminals of motoneurons
AMPK mediates early activation of the unfolded protein response through a positive feedback loop in palmitate-treated muscle cells
Early evolution of beetles regulated by the end-Permian deforestation
Fast adaptation of cooperative channels engendersHopf bifurcations in auditory hair cells
Mapping tumor spheroid mechanics in dependence of 3D microenvironment stiffness and degradability by Brillouin microscopy
Ubiquitin Proteasome Pathway annotation in Diaphorina citri can reveal potential targets for RNAi based pest management
Functional single cell selection and annotated profiling of dynamically changing cancer cells
Social and asocial learning in zebrafish are encoded by a shared brain network that is differentially modulated by local activation
Chromosome-level assembly of the common vetch reference genome (Vicia sativa)
Membrane permeability differentiation at the lipid divide
Multi-parameter optical imaging of immune cell activity in chimeric antigen receptor T-cell and checkpoint blockade therapies
Intermanual transfer of visuomotor learning is facilitated by a cognitive strategy
Neural dynamics of illusory tactile pulling sensations
Predictive regulation of cardiovascular system on emergence of auditory-motor interaction in young infants
Predicting Individual Traits from Unperformed Tasks
Individual alpha power predicts language comprehension
Dynamic metabolic network modeling of a mammalian cell cycle using time-course multi-omics data
Speckle illumination microscopy enables slide-free and non-destructive pathology of human lung adenocarcinoma
Ex Vivo Culture Models of Hidradenitis Suppurativa for defining molecular pathogenesis and treatment efficacy of novel drugs
Role of the reaction-structure coupling in temperature compensation of the KaiABC circadian rhythm
Nephronectin-Integrin α8 signaling is required for proper migration of periocular neural crest cells during chick corneal development
RNAi screening of RING/U-box domain ubiquitin ligases identifies critical regulators of stem cells and tissue regeneration in planarians
Oncogenic KRAS Requires Complete Loss of BAP1 Function for Development of Murine Intrahepatic Cholangiocarcinoma
Tissue-wide coordination of calcium signaling regulates the epithelial stem cell pool during homeostasis
Recording of cellular physiological histories along optically readable self-assembling protein chains
Multimodal tubulin binding by the yeast kinesin-8, Kip3, underlies its motility and depolymerization
De novo Prediction of Cell-Drug Sensitivities Using Deep Learning-based Graph Regularized Matrix Factorization
Superresolution microscopy reveals partial preassembly and subsequent bending of the clathrin coat during endocytosis
A stress-reduced passaging technique improves the viability of human pluripotent cells
The mechanochemical origins of the microtubule sliding motility within the kinesin-5 domain organization
Long-range migration of centrioles to the apical surface of the olfactory epithelium
Fetal cerebellar development: 3D morphometric analysis of fetal postmortem MRI among Chinese fetuses.
Topological Constraints on Noise Propagation in Gene Regulatory Networks
The fungicide Tebuconazole induces electromechanical cardiotoxicity in murine hearts
New markers for qPCR detection of the dinoflagellate Alexandrium catenella in Chile
On the Use of Z-Scores for Fine-Mapping with Related Individuals
Environmentally dependent and independent control of cell shape determination by Rho GTPase regulators in melanoma
Mast cell regranulation involves a metabolic switch promoted by the interaction between mTORC1 and a glucose-6-phosphate transporter
Structural and functional asymmetry of the neonatal cerebral cortex
A Standardized Protocol for Quantifying the Behavioral Dynamics of Food-seeking in Mice