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#PeerReview from @eLife of ???????? Universal markers support a long inter-domain branch between Archaea and Bacteria |
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#PeerReview from @eLife of ???????? Cannabinoid signaling modulation through JZL184 restores key phenotypes of a mouse model for Williams-Beuren syndrome |
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Chemo-mechanical Diffusion Waves Orchestrate Collective Dynamics of Immune Cell Podosomes |
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A chemical method to sequence 5-formylcytosine on RNA |
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#PeerReview from #GigaByte of ???????? De novo chromosome level assembly of the mule deer (Odocoileus hemionus) genome |
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#PeerReview from @ASAPbio_ of ???????? Pathogenic mutations in the chromokinesin KIF22 disrupt anaphase chromosome segregation |
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Zinc finger protein Zfp335 controls early T cell development and survival through beta-selection-dependent and -independent mechanisms |
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The Effect of COVID-19 on the Postdoctoral Experience: a comparison of pre-pandemic and pandemic surveys. |
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Computational Compensatory Mutation Discovery Approach: Predicting a PARP1 Variant Rescue Mutation |
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A deep learning framework for inference of single-trial neural population activity from calcium imaging with sub-frame temporal resolution |
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Artificial Intelligence Guided Conformational Mining of Intrinsically Disordered Proteins |
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pISA-tree - a data management framework for life science research projects using a standardised directory tree |
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Biomechanics of aging and osteoarthritic human knee ligaments |
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Genotyping strategies for detecting CRISPR mutations in polyploid species: a case study-based approach in hexaploid wheat |
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Uncovering Xenobiotics in the Dark Metabolome using Ion Mobility Spectrometry, Mass Defect Analysis and Machine Learning |
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Unravelling the regulation pathway of photosynthetic AB-GAPDH |
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Modern microbial mats from the Chihuahuan Desert provide insights into ecological stability throughout Earth's history |
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Alu repeats at the boundaries of regulatory elements shape the epigenetic environment of immune genes in T cells |
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Exploration of the antimicrobial synergy between selected natural substances on Streptococcus mutans to identify candidates for the control of dental caries |
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Optimizing transcranial direct current stimulation (tDCS) electrode position, size, and distance doubles the on-target cortical electric field: Evidence from 3000 Human Connectome Project models |
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Motor plans under uncertainty reflect a trade-off between maximizing reward and success |
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Stress deceleration theory: chronic adolescent stress exposure results in decelerated neurobehavioral maturation |
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Transient inhibition to light explains stronger V1 responses to dark stimuli |
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Artificial Intelligence uncovers carcinogenic human metabolites |
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Systematic Interrogation of Protein Refolding Under Cellular-Like Conditions |
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Unsupervised cell functional annotation for single-cell RNA-Seq |
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Transcriptomic Analysis of 3D Vasculature-On-A-Chip Reveals Paracrine Factors Affecting Vasculature Growth and Maturation |
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Parapatric speciation with recurrent gene flow of two sexual dichromatic pheasants |
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Respiratory Syncytial virus NS1 protein targets the transactivator binding domain of MED25 |
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Regnase-1 deficiency restrains Klebsiella pneumoniae infection by regulation of a Type I interferon response |
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Re-evaluating the actin-dependence of spectraplakin functions during axon growth and maintenance |
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Individual Stability of Pain- and Touch-Related Neuronal Gamma Oscillations |
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A novel mutation (E83Q) unlocks the pathogenicity of human alpha-synuclein fibrils and recapitulates its pathological diversity |
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RNA-Seq analysis identifies novel roles for the primary cilia gene SPAG17 and the SOX9 locus non-coding RNAs in systemic sclerosis |
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Cohesion in male singing behavior predicts group reproductive output in a social songbird |
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Conformational Changes in the Negative Arm of the Circadian Clock Correlate with Dynamic Interactomes Involved in Post-transcriptionally Regulated Processes |
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Single-Channel Permeability from Markovian Milestoning, Umbrella Sampling, and Voltage Simulations |
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A glycerol shunt functions as a glucose excess security valve in pancreatic β-cells |
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Organization and dynamics of the SpoVAEa protein, and its surrounding inner membrane lipids upon germination of Bacillus subtilis spores |
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Epigenetic changes in autoimmune monocytes contribute to disease and can be targeted by JAKinhibition |
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Multi-timescale biological learning algorithms train spiking neuronal network motor control |
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The Contributions of Eye Gaze Fixations and Target-Lure Similarity to Behavioral and fMRI Indices of Pattern Separation and Pattern Completion |
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A multiscale X-ray phase-contrast tomography dataset of whole human left lung |
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Active Segregation Dynamics in the Living Cell |
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Fast DNA-PAINT imaging using a deep neural network |
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cNap1 bridges centriole contact sites to maintain centrosome cohesion |
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Heat activation and inactivation of bacterial spores. Is there an overlap? |
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Distinct neurocognitive bases for social trait judgments of faces in autism spectrum disorder |
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Constructing threat probability, fear behaviour, and aversive prediction error in the brainstem. |
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A Comparison Study between Autism Spectrum Disorder and Typically Control in Graph Frequency Bands Using Graph and Triadic Interaction Metrics |
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Balancing selection and the crossing of fitness valleys in structured populations: diversification in the gametophytic self-incompatibility system |
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A ROS-Ca2+ signalling pathway identified from a chemical screen for modifiers of sugar-activated circadian gene expression. |
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The annotation and analysis of complex 3D plant organs using 3DCoordX |
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Substrate dependent homeostatic control of c-di-AMP synthase (MsDisA) and hydrolase (MsPDE) from Mycobacterium smegmatis |
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Systematic in silico discovery of novel solute carrier-like proteins from proteomes |
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A Method for Computationally Constructing Eukaryotic Synthetic Signal Peptide Sequences |
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Strict adherence to Mendel's First Law across a large sample of human sperm genomes |
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Host exposure to symbionts and ecological drift generate divergence in parasite community assembly |
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Circadian regulation of lung repair and regeneration |
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A large scale, multiple genome comparison of acidophilic Archaea (pH <= 5.0) extends our understanding of oxidative stress responses in polyextreme environments |
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Listeria spp. Isolated from Soil Samples Collected in the Great Smoky Mountains |
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Oscillatory population-level activity of dorsal raphe serotonergic neurons sculpts sleep structure |
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Designing and comparing cleaning pipelines for TMS-EEG data: a theoretical overview and practical example |
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The P600, but not N400, is modulated by sustained attention |
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Reset Networks: Emergent Topography in Networks of Convolutional Neural Networks |
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Frontal but not parietal cortex is required for decisions under risk |
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Glutamate-Weighted Magnetic Resonance Imaging (GluCEST) Detects Effects of Transcranial Magnetic Stimulation to the Motor Cortex |
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Oxygenated hemoglobin signal provides greater predictive performance of experimental condition than de-oxygenated |
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Non-invasive visualization of amyloid-beta deposits in Alzheimer amyloidosis mice using magnetic resonance imaging and fluorescence molecular tomography |
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Putting the theory into 'burstlet theory': A biophysical model of bursts and burstlets in the respiratory preBötzinger complex |
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Beyond gradients: Noise correlations control Hebbian plasticity to shape credit assignment |
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Theta activity during encoding interacts with NREM sleep oscillations to predict memory generalization |
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Disruption Of Proprioceptive Information During Electrical Stimulation Of The Cutaneous Afferents |
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Assessment of temporal complexity in functional MRI between rest and task conditions |
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Doppler Slicing for Ultrasound Super-Resolution Without Contrast Agents |
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Transcriptome and fatty-acid signatures of adipocyte hypertrophy and its non-invasive MR-based characterization in human adipose tissue |
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The effect of external stimulation on functional networks in the aging healthy human brain |
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Microscopic Characterization of the Chloride Permeation Pathway in the Human Excitatory Amino Acid Transporter 1 (EAAT1) |
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PDFGRα+ Stromal Cells Promote Salivary Gland Proacinar Differentiation Through FGF2-dependent BMP7 Signaling. |
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Heat stress leads to rapid lipid remodelling and transcriptional adaptations in Nicotiana tabacum pollen tubes |
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Self-organization of in vitro neuronal assemblies drives to complex network topology |
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The natural compound TMYX reduces SAN cells rate by antagonizing the cAMP modulation of f-channels |
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Sequence characterization of eccDNA content in glyphosate sensitive and resistant Palmer amaranth from geographically distant populations |
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Shotgun metagenomics of soil invertebrate communities reflects taxonomy, biomass and reference genome properties |
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Mosaic loss of chromosome Y in aged human microglia. |
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Set1-mediated histone H3K4 methylation is required for azole induction of the ergosterol biosynthesis genes and antifungal drug resistance in Candida glabrata. |
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Allele segregation analysis of F1 hybrids between independent Brassica allohexaploid lineages |
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A tripartite structure, the complex nuclear receptor element (cNRE), is a cis-regulatory module of viral origin required for atrial chamber preferential gene expression |
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Abcc6 null mice a model for mineralization disorder PXE show vertebral osteopenia without enhanced intervertebral disc calcification with aging |
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Disorder in Ca2+ Release Unit Locations Confers Robustness but Cuts Flexibility of Heart Pacemaking |
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Characterization and simulation of metagenomic nanopore sequencing data with Meta-NanoSim |
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On the hindlimb biomechanics of the avian take-off leap |
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Evidence for the role of transcription factors in the co-transcriptional regulation of intron retention |
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Genetic mapping of genotype-by-ploidy effects in Arabidopsis thaliana |
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Indirect effects of parental conflict on conspecific offspring development |
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Interrogating Genomic Data in the Phylogenetic Placement of Treeshrews Reveals Potential Sources of Conflict |
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CLASS-II KNOX genes coordinate spatial and temporal patterns of the tomato ripening |
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Connexinplexity: The spatial and temporal expression of connexin genes during vertebrate organogenesis |
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The developmentally-timed decay of an essential microRNA family is seed sequence-dependent |
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WWOX-Mediated Degradation of AMOTp130 Negatively Affects Egress of Filovirus VP40 VLPs |
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A Biophysical Model of Nonquantal Transmission at the Vestibular Hair Cell-Calyx Synapse: KLV currents Modulate Fast Electrical and Slow K+ potentials in the Synaptic Cleft |
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Passive Exposure Sparsifies Neural Activity in the Primary Visual Cortex |
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A human kinase yeast array for the identification of kinases modulating phosphorylation-dependent protein-protein interactions |
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Smart soils to observe hidden rhizosphere processes |
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Metaeffector interactions modulate the type III effector-triggered immunity load of Pseudomonas syringae |
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Partial prevention of glucocorticoid-induced osteocyte deterioration with osteocrin gene therapy |
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Preclinical and Toxicology Studies of BRD5529, a Selective Inhibitor of CARD9 |
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A chemerin peptide analog stimulates tumor growth in two xenograft mouse models of human colorectal carcinoma |
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Study on the effect of a triple cancer treatment of propolis, thermal cycling-hyperthermia, and low-intensity ultrasound on PANC-1 cells |
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Restoring single-molecule localizations with wavefront sensing adaptive optics for deep-tissue super-resolution imaging |
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Heterogeneous run-and-tumble motion accounts for transient non-Gaussian super-diffusion in haematopoietic multi-potent progenitor cells |
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nucGEMs probe the biophysical properties of the nucleoplasm |
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TCR-BERT: learning the grammar of T-cell receptors for flexible antigen-binding analyses |
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DETIRE: A Hybrid Deep Learning Model for identifying Viral Sequences from Metagenomes |
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Robust Identification of Temporal Biomarkers in Longitudinal Omics Studies |
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Substrate stiffness controls the cell cycle of human mesenchymal stem cells via cellular traction |
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Validity of freehand three-dimensional ultrasound system in measurement of three-dimensional surface shape of shoulder muscles |
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Weighted Shoes in the Wild: Initial Insights into the Relationship Between the Effort of Walking and the Amount of Walking Performed |
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A genome assembly of the Atlantic chub mackerel (Scomber colias): a valuable teleost fishing resource |
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A Time-calibrated Firefly (Coleoptera: Lampyridae) Phylogeny: Using Genomic Data for Divergence Time Estimation |
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The global spread and invasion capacities of alien ants |
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Polyethylene glycol (PEG) methods are superior to acidification for secondary concentration of Adenovirus and MS2 in water |
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Loss of self-tolerance leads to altered gene expression and IMD pathway activation in Drosophila melanogaster |
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T cell-intrinsic vitamin A metabolism and its signaling are targets for memory T cell-based cancer immunotherapy |
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Insights into the trafficking of human leukocytes to colostrum evidences a modulation of the B lymphocyte compartment in obesity |
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Antigen presentation by type 3 innate lymphoid cells instructs the differentiation of gut microbiota-specific regulatory T cells |
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Algorithmic Parameter Estimation and Uncertainty Quantification for Hodgkin-Huxley Neuron Models |
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Glyphosate and its formulations Roundup Bioflow and RangerPro alter bacterial and fungal community composition in the rat caecum microbiome |
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Proteolysis Targeting Chimeras With Reduced Off-targets |
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Label-free imaging of collagen fibers in tissue slices using phase imaging with computational specificity |
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Cell Painting predicts impact of lung cancer variants |
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Simultaneous multicolor DNA-PAINT without sequential fluid exchange using spectral demixing |
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Model for ring closure in ER tubular network dynamics |
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Optimizing reaction coordinate by flux maximization in the transition path ensemble |
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Adaptive ratchets and the evolution of molecular complexity |
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Glycosaminoglycans and glycoproteins influence the elastic response of synovial fluid nanofilms on model oxide surfaces |
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DomBpred: protein domain boundary predictor using inter-residue distance and domain-residue level clustering |
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Nonmetric ANOVA: a generic framework for analysis of variance on dissimilarity measures |
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STRling: a k-mer counting approach that detects short tandem repeat expansions at known and novel loci |
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Model-checking ecological state-transition graphs |
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Swarm learning for decentralized artificial intelligence in cancer histopathology |
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Parental control: ecology drives plasticity in parental response to offspring signals |
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Invertebrate DNA methylation and gene regulation |
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Pre-metazoan origin of neuropeptide signalling |
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A 1-bp deletion in bovine QRICH2 causes low sperm count and immotile sperm with multiple morphological abnormalities |
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Genetic control of kinetochore-driven microtubule growth in Drosophila mitosis |
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Functional divergence and spectral tuning of microbial rhodopsins from an ancestral proton pump |
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Historical specimens and the limits of subspecies phylogenomics in the New World quails (Odontophoridae) |
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Recent Urban Development Reduces Bee Abundance and Diversity |
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Factors affecting virus prevalence in honey bees in the Pacific-Northwest, USA |
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Filtration extraction method using microfluidic channel for measuring environmental DNA |
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Patient induced pluripotent stem cell-derived hepatostellate organoids establish a basis for liver pathologies in telomeropathies |
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The spotlight of attention turns from rhythmic exploration-exploitation to a stable exploitation state |
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Longitudinal changes of ADHD symptoms in association with white matter microstructure: a tract-specific fixel-based analysis |
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Analytical kinetic model of native tandem promoters in E. coli |
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Induction of virus-induced gene silencing and in planta validation in cucurbits using the CFMMV-Cm vector |
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VTA-IC dopaminergic inputs enhances the salience to consolidate aversive but not appetitive taste recognition memory via D1 receptors |
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Joint estimation of selection intensity and mutation rate under balancing selection withapplications to HLA |
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Scoping the Line Up: A Comparison of Biomonitoring Methodologies for Surf Zone Fish Communities |
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STAT3 and HIF1α cooperatively mediate the transcriptional and physiological responses to hypoxia |
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Human-Plant Coevolution: A modelling framework for theory-building on the origins of agriculture |
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Cultured deep-sea PVC bacteria shed light on eukaryogenesis |
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What is the best fitness measure in wild populations? A case study on the power of short-term fitness proxies to predict reproductive value |
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Monocarboxylate Transporter 1 (MCT1) mediates succinate export in the retina |
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Pre-implantation mouse embryo movement under hormonally altered conditions |
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IGF1 Signaling in Temporomandibular Joint Fibrocartilage Stem Cells Regulates Cartilage Growth and Homeostasis in Mice |
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ARL3 Mediates BBSome Ciliary Turnover by Promoting Its Outward Diffusion through the Transition Zone |
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Cleavage of PGAM5 by the intramembrane protease PARL is governed by transmembrane helix dynamics and oligomeric state |
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Structural features within the NORAD long noncoding RNA underlie efficient repression of Pumilio activity |
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Mitochondrial dysfunction promotes alternative gasdermin D-mediated inflammatory cell death and susceptibility to infection |
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Nonenzymatic loop-closing ligation generates RNA hairpins and is a template-free way to assemble functional RNAs |
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Fusobacterium nucleatum infection induces pancreatic cancer cell proliferation and migration through regulation of host cytokine signaling |
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TK216 targets microtubules in Ewing sarcoma cells |
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Inactivation effect and damage of multi-irradiance by UVCLED on Acinetobacter baumannii |
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evSeq: Cost-Effective Amplicon Sequencing of Every Variant in a Protein Library |
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Chemical Reversible Crosslinking Enables Measurement of RNA 3D Distances and Alternative Conformations in Cells |
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Polygalacturonase production enhancement by Piriformospora indica from sugar beet pulp under submerged fermentation using surface methodology |
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Loss of zinc transporters ZIP1 and ZIP3 augments platelet reactivity in response to G protein-coupled receptor agonists and accelerates thrombus formation in vivo |
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Improved resolution of recalcitrant nodes in the animal phylogeny through the analysis of genome gene content and morphology |
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The sperm protein Spaca6 is essential for fertilization in zebrafish |
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Enhancer and super-enhancer landscape in polycystic kidney disease |
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A Comprehensive Roadmap Towards Generation of Influenza B Reporter Assay Using a Single DNA Polymerase Based Cloning of Reporter RNA Construct |
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TAILS identifies candidate substrates and biomarkers of ADAMTS7, a therapeutic protease target in coronary artery disease |
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RIF1-ASF1-mediated high-order chromatin structure safeguards genome integrity |
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Metformin Suppresses SARS-CoV-2 in Cell Culture |
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A marine fungus efficiently degrades polyethylene |
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Replication protein Rep provides selective advantage to viruses in the presence of CRISPR-Cas immunity |
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A scalable analytical approach from bacterial genomes to epidemiology |
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Human macrophage polarization determines bacterial persistence of Staphylococcus aureus in a liver-on-chip-based infection model |
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Progressive sub-MIC Exposure of Klebsiella pneumoniae 43816 to Cephalothin Induces the Evolution of beta-lactam Resistance without Acquisition of beta-lactamase Genes |
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Three orphan histidine kinases inhibit Clostridioides difficile sporulation |
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The proton motive force determines Escherichia coli's robustness to extracellular pH |
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From sequence to yield: deep learning for protein production systems |
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Eliminating fibroblast activation protein-α expressing cells by photoimmunotheranostics |
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Histidine-rich protein 2: a new pathogenic factor of Plasmodium falciparum malaria |
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Evolution of enzyme levels in metabolic pathways: A theoretical approach. Part 2 |
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Multitrophic higher-order interactions modulate species persistence |
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DeepProjection: Rapid and structure-specific projections of tissue sheets embedded in 3D microscopy stacks using deep learning |
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A non-transcriptional function of Yap orchestrates the DNA replication program |
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Effortless integration of probabilistic visual input |
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An insight into new glycotherapeutic in glial inflammation: Understanding the role of glycosylation from acute to chronic phase of inflammation |
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Slow fluctuations in ongoing brain activity decrease in amplitude with ageing yet their impact on task-related evoked responses is dissociable from behaviour |
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Differential replay for reward and punishment paths predicts approach and avoidance |
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Cytotoxicity mechanisms and composition of the glyphosate formulated herbicide RangerPro |
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High diversity of pimpline parasitoid wasps (Hymenoptera, Ichneumonidae, Pimplinae) from the lowermost Eocene Fur Formation |
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BOXR1030, an anti-GPC3 CAR with exogenous GOT2 expression, shows enhanced T cell metabolism and improved antitumor activity |
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Characterization of plasma circulating small extracellular vesicles in patients with metastatic solid tumors and newly diagnosed brain metastasis. |
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Double mutant of chymotrypsin inhibitor 2 stabilized through increased conformational entropy |
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Deciphering a hexameric protein complex with Angstrom optical resolution |
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TIS transformer: Re-annotation of the human proteome using deep learning |
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SubcellulaRVis: an app to visualize subcellular compartment enrichment |
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Semi-supervised single-cell cross-modality translation using Polarbear |
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PURC v2.0: a program for improved sequence inference for polyploid phylogenetics and other manifestations of the multiple-copy problem |
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ZARP: An automated workflow for processing of RNA-seq data |
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Epigenetic machinery is functionally conserved in cephalopods |
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Ecological changes have driven biotic exchanges across the Indian Ocean |
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Multiple adaptive solutions to face climatic constraints: novel insights in the debate over the role of convergence in local adaptation |
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The influence of somatosensory and auditory evoked potentials on concurrent transcranial-magnetic stimulation electroencephalography recordings |
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kTMP: A New Non-invasive Magnetic Induction Method to Modulate Cortical Excitability. |
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Trajectory of rich club properties in structural brain networks |
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Towards a catalog of pome tree architecture genes: the draft 'd'Anjou' genome (Pyrus communis L.) |
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The evidence for anthocyanins in the betalain-pigmented genus Hylocereus is weak |
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Prostaglandin PGE2 receptor EP4 regulates microglial phagocytosis and increases susceptibility to diet-induced obesity |
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In silico drug discovery strategies identified ADMET properties of decoquinate RMB041 and its potential drug targets against Mycobacterium Tuberculosis |
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Adhesion strength between cells regulate non-monotonic growth by a biomechanical feedback mechanism |
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Mechanistic insights into global suppressors of protein folding defects |
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VIVID: a web application for variant interpretation and visualisation in multidimensional analyses |
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scCODE: an R package for personalized differentially expressed gene detection on single-cell RNA-sequencing data |
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Evaluating the contribution of aestivation to the persistence of malaria mosquitoes through the Sahelian dry season using stable isotopes |
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Broadly-neutralizing antibodies that bind to the influenza hemagglutinin stalk domain enhance the effectiveness of neuraminidase inhibitors via Fc-mediated effector functions |
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Impaired oligodendrocyte maturation is an early feature in SCA3 disease pathogenesis |
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Anatomical connectivity along the anterior-posterior axis of the human hippocampus: new insights using quantitative fibre-tracking. |
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Not so fast: Limited validity of deep convolutional neural networks as in silico models for human naturalistic face processing |
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Analysis of the computational strategy of a detailed laminar cortical microcircuit model for solving the image-change-detection task |
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Hidden temporal structure of the ongoing task impacts detection strategy and is reflected in pupillary dynamics |
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Awake ripples enhance emotional memory encoding in the human brain |
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Sharing individualised template MRI data for MEG source reconstruction: a solution for open data while keeping subject confidentiality |
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Proteomic analysis of liver tissue reveals Aeromonas hydrophila infection mediated modulation of host metabolic pathways in Labeo rohita |
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Suppressed prefrontal neuronal firing variability and impaired social representation in IRSp53-mutant mice |
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Nanoviricides platform technology based NV-CoV-2 polymer increases the half-life of Remdesivir in vivo |
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Integrative Omics Analysis Reveals the Immunomodulatory Effects of the Parasitic Dinoflagellate Hematodinium on Crustacean Immunity |
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Stimulus-induced narrow-band gamma oscillations in humans can be recorded using open-hardware low-cost EEG amplifier |
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Affinity Scores: An Individual-centric Fingerprinting Framework for Neuropsychiatric Disorders |
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Micro-state-based neural decoding of speech categorization using Bayesian non-parametrics |
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The output of interneurons in the primary visual cortex is best reflected by pre-synaptic activity, not somatic activity |
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Body shape as a visual feature: evidence from spatially-global attentional modulation in human visual cortex |
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Modulation of hippocampal network oscillation by PICK1-dependent cell surface expression of mGlu3 receptors |
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Susceptibility monitoring and the molecular characterization of resistance of Spodoptera frugiperda (Lepidoptera: Noctuidae) to lambda-cyhalothrin and chlorpyrifos |
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Multiple trajectory alignment reconstructs disease dynamics for discovery and clinical benefit |
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A general model of the dynamics of genes with dual σ factor preference |
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Identification of antibiotic resistance proteins via MiCId's augmented workflow. A mass spectrometry-based proteomics approach |
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Automated assembly scaffolding elevates a new tomato system for high-throughput genome editing |
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Remodeling of dermal adipose tissue alleviates cutaneous toxicity induced by anti-EGFR therapy |
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Gene expression based inference of drug resistance in cancer |
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The evolution of genomic, transcriptomic, and single-cell protein markers of metastatic upper tract urothelial carcinoma |
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Characterizing disease-associated human proteins without available protein structures or homologues |
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A3D Database: Structure-based Protein Aggregation Predictions for the Human Proteome |
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Morpholino-mediated knockdown of the brain mineralocorticoid receptor affects glucocorticoid signaling and neuroplasticity in wild ocellated wrasse (Symphodus ocellatus) |
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The natural adaptation and human selection history of African sheep genomes |
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Net charges of the ribosomal proteins of the S10 and spc clusters of halophiles are inversely related to the degree of halotolerance |
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Kinetic networks identify key regulatory nodes and transcription factor functions in early adipogenesis |
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Trait Association and Prediction Through Integrative K-mer Analysis |
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A new lineage of non-photosynthetic green algae with extreme organellar genomes |
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Monophyly of Diverse Bigyromonadea and their Impact on Phylogenomic Relationships Within Stramenopiles |
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Effect of RNA preservation methods on RNA quantity and quality of field collected avian whole blood |
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Integrating transcriptomes to investigate genes associated with adaptation to aquatic environments, and assess phylogenetic conflict and whole-genome duplications in Alismatales |
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Genetic and antigenic characterization of an expanding H3 influenza A virus clade in US swine visualized by Nextstrain |
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Phylogenomic analyses using genomes and transcriptomes do not resolve relationships among major clades in Phrymaceae |
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Impacts of Taxon-Sampling Schemes on Bayesian Molecular Dating under the Unresolved Fossilized Birth-Death Process |
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Quantifying asymmetry in non-symmetrical morphologies, with an example from Cetacea |
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The relationship between land cover and microbial community composition in European lakes |
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Edaphic controls on genome size and GC content of bacteria in soil microbial communities |
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Landscape structure and dispersal rate drive large scale catastrophic shifts in spatially explicit metapopulations |
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How do avian embryos resume development following diapause? A new role for TGF-β in regulating pluripotency-related genes |
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Esrrγa regulates nephron development and ciliogenesis by controlling prostaglandin synthesis and cooperation with Ppargc1a |
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Robust temporal map of human in vitro myelopoiesis using single-cell genomics |
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Methylglyoxal Induces Endothelial Dysfunction via Stunning |
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LiveCellMiner: A New Tool to Analyze Mitotic Progression |
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Common variation in EDN1 regulatory regions highlights the role of PPARγ as a key regulator of Endothelin in vitro |
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Human Cytomegalovirus modifies placental small extracellular vesicle secretion and composition towards a proviral phenotype to enhance infection of fetal recipient cells |
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Vitronectin acts as a key regulator of adhesion and migration in umbilical cord-derived MSCs under different stress conditions |
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AMPK promotes Arf6 activation in a kinase-independent manner upon energy deprivation |
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Revisiting the effect of pharmaceuticals on transmission stage formation in the malaria parasite Plasmodium falciparum |
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When less is more - Endogenous tagging with TurboID increases the sensitivity of proximity labelling-based experiments |
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Cortical microtubule pulling forces contribute to the union of the parental genomes in the C. elegans zygote |
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Ribosome profiling of porcine reproductive and respiratory syndrome virus reveals novel features of viral gene expression |
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Systems medicine dissection of chromosome 1q amplification reveals oncogenic regulatory circuits and informs targeted therapy in cancer |
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Cooperative protein allosteric transition mediated by a fluctuating transmission network |
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A Thin-Film Lubrication Model for Biofilm Expansion Under Strong Adhesion |
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Adversarial domain translation networks enable fast and accurate large-scale atlas-level single-cell data integration |
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CRAFT: a bioinformatics software for custom prediction of circular RNA functions |
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Structural comparative modeling of multi-domain ΔF508 CFTR |
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Meta-Transcriptome Detector (MTD): a novel pipeline for metatranscriptome analysis of bulk and single-cell RNAseq data |
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Missense variants reveal functional insights into the human ARID family of gene regulators |
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FDJD: RNA-Seq Based Fusion Transcript Detection Using Jaccard Distance |
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A multiplexed cell-free assay to screen for antimicrobial peptides in double emulsion droplets |
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Virtual reality validation of naturalistic modulation strategies to counteract fading in retinal stimulation |
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Hippocampal Neuropeptide Y2 receptor blockade improves spatial memory retrieval and modulates limbic brain metabolism |
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Trimethylamine N-Oxide (TMAO) links peripheral insulin resistance and cognitive deficiencies in a senescence accelerated mouse model |
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Effects of food availability cycles on phase and period of activity/rest rhythm in Drosophila melanogaster |
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Effects of crude oil on juvenile threespine stickleback somatic and immune development |
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2-photon-fabricated nano-fluidic traps for extended detection of single macromolecules and colloids in solution |
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Mapping morphological malformation to genetic dysfunction in blood vessel organoids with 22q11.2 Deletion Syndrome |
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#PeerReview from @eLife of ???????? Reduced calcium storage blunts calcium signaling in Toxoplasma bradyzoites and impedes motility and egress |
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Transcriptomic and proteomic analysis of marine nematode Litoditis marina acclimated to different salinities |
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Malathion-resistant Tribolium castaneum has enhanced response to oxidative stress, immunity, and fitness |
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Tunable Transcription Factor Library for Robust Quantification of Gene Expression Dynamics in E. coli |
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HSP90 function is required for T2R bitter taste receptor nitric oxide production and innate immune responses in human airway epithelial cells and macrophages |
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A Poor Research Landscape Hinders the Progression of Knowledge and Treatment of Reproductive Diseases |
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Aerobic glycolysis in cancer cells supplies ATP while preventing excess metabolic thermogenesis |
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Recapitulation of patient-specific 3D chromatin conformation using machine learning and validation of identified enhancer-gene targets |
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Association of EBV (Type 1 and 2) with Histopathological Outcomes in Breast Cancer in Pakistani Women |
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Reconstructing mutational lineages in breast cancer by multi-patient-targeted single cell DNA sequencing |
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Extending and using anatomical vocabularies in the Stimulating Peripheral Activity to Relieve Conditions (SPARC) project |
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Marker-free characterization of single live circulating tumor cell full-length transcriptomes |
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FastQTLmapping: an ultra-fast package for mQTL-like analysis |
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Sensitive identification of known and unknown protease activities by unsupervised linear motif deconvolution |
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SC2MeNetDrug: A computational tool to uncover inter-cell signaling targets and identify relevant drugs based on single cell RNA-seq data |
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WebSeq: A Genomic Data Analytics Platform for Monogenic Disease Discovery |
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Hierarchical organization of rhesus macaque behavior |
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Trajectory Recording and Analysis System for Cockroach Robot |
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#PeerReview from @eLife of ???????? Cocaine causes rapid remodeling of dopaminergic axons, synapses, and mitochondria |
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Holographic imaging of mitochondrial optical density in living cells reveals that the Mitochondrial Permeability Transition is a two-stage process |
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Complementary population codes in the dorsal and ventral hippocampus during associative learning |
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The natural frequencies of the resting human brain: an MEG-based atlas |
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Anticipatory dynamics in the human brain guide foraging for primary rewards |
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Neural Mechanisms of Learning are Critically Dependent on Sleep |
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Upregulation of CREB1 and FOXO1 transcription factor pathways in Neuregulin-1 mediated neuroprotection following ischemic stroke |
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Periodic ethanol supply as a path towards unlimited lifespan of C.elegans dauer larvae |
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Northern Cerrado Native Vegetation is a Refuge for Birds Under Current Climate Change |
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Resistance profiling of Aspergillus fumigatus to olorofim indicates absence of intrinsic resistance and unveils the molecular mechanisms of acquired olorofim resistance |
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Orthogonal control of gene expression in plants using synthetic promoters and CRISPR-based transcription factors |
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Among retroviral integrases prototype foamy virus integrase displays unique biochemical activities |
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Dithiothreitol causes toxicity in C. elegans by modulating the methionine-homocysteine cycle |
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Getting close to nature - Plasmodium knowlesi reference genome sequences from contemporary clinical isolates |
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SARS-CoV-2 RdRp is a versatile enzyme with proofreading activity and ability to incorporate NHC into RNA by using diphosphate form molnupiravir as a substrate |
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IFITM dependency of SARS-CoV-2 variants of concern |
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An assessment of the evidence for antibacterial activity of stinging nettle (Urtica dioica) extracts |
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Membrane adaptation in the hyperthermophilic archaeon Pyrococcus furiosus relies upon a novel strategy involving glycerol monoalkyl glycerol tetraether lipids |
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Reconstitution of Spiroplasma swimming by expressing two bacterial actins in synthetic minimal bacterium |
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The mouse mammary tumor virus intasome exhibits distinct dynamics on target DNA |
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Temperature-responsive structural reversibility of FGF21 and structure-based design of its variant with enhanced potency |
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NUDT18 catalyzes hydrolysis of active metabolites of the antivirals Remdesivir and Ribavirin |
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DNA Breaks and Gaps Target Retroviral Integration |
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Global Mutational Sweep of SARS-CoV-2: from Chaos to Order |
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Estrogen-related receptor alpha and Rplp1 ribosome protein-dependent translation coordinately regulate starvation response and decrease NASH progression |
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Recognition and deubiquitination of free 40S for translational reset by Otu2 |
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The Delta variant of SARS-CoV-2 maintains high sensitivity to interferons in human lung cells |
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Genome-wide identification of novel sRNAs in Streptococcus mutans |
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Identification of shared bacterial strains in the vaginal microbiota of reproductive-age mothers and daughters using genome-resolved metagenomics |
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Tuning spherical cells into kinking helices in wall-less bacteria |
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Microglia do not restrict SARS-CoV-2 replication following infection of the central nervous system of K18-hACE2 transgenic mice |
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Susceptibility of sheep to experimental co-infection with the ancestral lineage of SARS-CoV-2 and its alpha variant |
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NMR metabolomics of symbioses between bacterial vaginosis associated bacteria |
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The mycobacterial mutasome: composition and recruitment in live cells |
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Identification of a minimal biomarker profile in head-and-neck squamous cell carcinoma tumors |
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Predicting SARS-CoV-2 epitope-specific TCR recognition using pre-trained protein embeddings |
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BSG/CD147 and ACE2 receptors facilitate SARS-CoV-2 infection of human iPS cell-derived kidney podocytes |
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Recent zoonotic spillover and tropism shift of a Canine Coronavirus is associated with relaxed selection and putative loss of function in NTD subdomain of spike protein. |
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Tunneling nanotubes provide a novel route for SARS-CoV-2 spreading between permissive cells and to non-permissive neuronal cells. |
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A Novel Ex Vivo Peritoneal Model to Investigate Mechanisms of Peritoneal Metastasis in Gastric Adenocarcinoma |
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Collective chemotaxis in a Voronoi model for confluent clusters |
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Simultaneous stereo-EEG and high-density scalp EEG recordings to study the effects of intracerebral stimulation parameters |
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Auricular transcutaneous vagus nerve stimulation acutely modulates brain connectivity in mice |
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Differential Methods for Assessing Sensitivity in Biological Models |
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Critical role of H3K27 methylation in cell fate determination of two cell lineages in male gametophyte |
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Transgenerational effects decrease larval resilience to ocean acidification and warming but juvenile European sea bass could benefit from higher temperatures in the NE Atlantic |
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On biological flow networks: Antagonism between hydrodynamic and metabolic stimuli as driver of topological transitions. |
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Contingency and selection in mitochondrial genome dynamics |
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Reconstructing heterogeneous pathogen interactions from co-occurrence data via statistical network inference |
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Rhythmic auditory stimulation rescues cognitive flexibility in mutant mice with impaired gamma synchrony |
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Home literacy environment mediates the relationship between socioeconomic status and white matter structure in infants |
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Channel opening duration in adult muscle nAChRs determined by activated external ACh binding site |
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Not Quite All in Our Head: Intervention is a Better Predictor of tDCS Mind-Wandering Effects than Subjective Beliefs About Experimental Results |
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Distinct roles for two Caenorhabditis elegans acid-sensing ion channels in an ultradian clock |
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CINmetrics: An R package for chromosomal instability analysis |
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A copula based topology preserving graph convolution network for clustering of single-cell RNA-seq data |
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BamToCov: an efficient toolkit for sequence coverage calculations |
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Whokaryote: distinguishing eukaryotic and prokaryotic contigs in metagenomes based on gene structure |
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A Post-hurricane Quantitative Assessment of the Red-bellied Racer (Alsophis rufiventris) on Saba and Comparison with St. Eustatius |
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Emotional ego- and altercentric biases in high-functioning autism spectrum disorder: Behavioral and neurophysiological evidence |
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#PeerReview from @ASAPbio_ of ???????? Optogenetic control of the Bicoid morphogen reveals fast and slow modes of gap gene regulation |
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#PeerReview from @eLife of ???????? A neural hub that coordinates learned and innate courtship behaviors |
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Estimating the Mosquito Density in Guangzhou city, China |
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A Marmoset Model for Mycobacterium avium Complex Pulmonary Disease |
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Molecular dynamics simulations reveal the selectivity mechanism of structurally similar agonists to TLR7 and TLR8 |
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Essential functions of MLL1 and MLL2 in retinal development and cone cell maintenance |
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Min waves without MinC can pattern FtsA-FtsZ filaments on model membranes |
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Protein Engineering with A Glycosylation Circuit Enables Improved Enzyme Characteristics |
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An atypical NLR protein modulates the NRC immune receptor network |
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Effector loss drives adaptation of Pseudomonas syringae pv. actinidiae to Actinidia arguta |
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A cell wall-associated gene network shapes leaf boundary domains |
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Genetic coordination of sperm morphology and seminal fluid proteins promotes male reproductive success in Drosophila melanogaster |
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Efficient inhibition of cell proliferation and promotion of apoptosis requires continuous treatment with abemaciclib. |
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Wolbachia endosymbionts in two Anopheles species indicates independent acquisitions and lack of prophage elements |
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Mobilome-driven segregation of the resistome in biological wastewater treatment |
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Investigating Carboxysome Morphology Dynamics with a Rotationally Invariant Variational Autoencoder |
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Loss of soluble guanylyl cyclase in platelets contributes to atherosclerotic plaque formation and vascular inflammation |
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Engraftment of allotransplantated tumour cells in adult rag2 mutant Xenopus tropicalis |
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MICU1 occludes MCU in the mitochondrial calcium uniporter complex |
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The effect of sequencing and assembly on the inference of horizontal gene transfer on chromosomal and plasmid phylogenies |
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Bacteria but not fungi communities differ among perennial grassland ecotypic rhizosphere under abiotic environmental stress |
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Cryo-EM of the yeast VO complex reveals distinct binding sites for macrolide V-ATPase inhibitors |
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Structure and mechanism of oxalate transporter OxlT in an oxalate-degrading bacterium in the gut microbiota |
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Structure of the Quenched Cyanobacterial OCP-Phycobilisome Complex |
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A Cryptic K48 Ubiquitin Chain Binding Site on UCH37 is Required for its Role in Proteasomal Degradation |
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Structure and functionality of a multimeric human COQ7:COQ9 complex |
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Structures of the Cyanobacterial Phycobilisome |
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Live imaging of the co-translational recruitment of XBP1 mRNA to the ER and its processing by diffuse, non-polarized IRE1a. |
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Genome editing of Capsaspora owczarzaki suggests an ancestral function of the Hippo signaling effector YAP/TAZ/Yorkie in cytoskeletal dynamics but not proliferation |
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Nieman-Pick Type C2 proteins in Aedes aegypti: Their Structure-Function relationships and Expression in Uninfected versus Virus-infected Mosquitos |
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Bacteriophage cocktails displayed protective effects against soft rot-causing Pectobacterium sp. |
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Cryptococcus neoformans capsule regrowth experiments reveal dynamics of enlargement and architecture |
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Ly6Chi monocytes are metabolically reprogrammed in the blood during inflammatory stimulation allowing for macrophage lineage commitment |
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Spatially regulated protease activity in lymph nodes renders B cell follicles a sanctuary for retention of intact antigens |
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Learning a new class of multisensory associations: High-density electrophysiological mapping of the temporal course of audio-visual object processing. |
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A live attenuated influenza virus-vectored intranasal COVID-19 vaccine provides rapid, prolonged, and broad protection against SARS-CoV-2 infection |
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Built on sand: the shaky foundations of simulating single-cell RNA sequencing data |
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Deep embedding and alignment of protein sequences |
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Structural and functional characterization of NEMO cleavage by SARS-CoV-2 3CLpro |
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Viral E Protein Neutralizes BET Protein-Mediated Post-Entry Antagonism of SARS-CoV-2 |
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Full protection against all four SARS-CoV-2 variants of concern (VOC) in hamsters requires revision of spike antigen used for vaccination. |
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Mutagenic distinction between the receptor-binding and fusion subunits of the SARS-CoV-2 spike glycoprotein |
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#COVIDisAirborne: AI-Enabled Multiscale Computational Microscopy of Delta SARS-CoV-2 in a Respiratory Aerosol |
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Hypoxia classifier for transcriptome datasets |
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pGlycoQuant with a deep residual network for precise and minuscule-missing-value quantitative glycoproteomics enabling the functional exploration of site-specific glycosylation |
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Genome-wide H3K9 Acetylation Level Increases with Age-Dependent Senescence of Flag Leaf in Rice (Oryza sativa) |
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Single-sample proteome enrichment enables missing protein recovery and phenotype association |
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Reassembling a cannon in the DNA defense arsenal: genetics of StySA, a BREX phage exclusion system in Salmonella lab strains |
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Non-conventional serine protease activity of the CXC chemokine-cleaving streptococcal enzyme, SpyCEP |
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Word structure tunes electrophysiological and hemodynamic responses in the frontal cortex |
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Ca2+-inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM |
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Determination of nuclear position by the arrangement of actin filaments using deep generative networks |
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CLMB: deep contrastive learning for robust metagenomic binning |
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Liver ductal organoids reconstruct intrahepatic biliary trees in decellularized liver grafts. |
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Numerous expansions in TRP ion channel diversity highlight widespread evolution of molecular sensors in animal diversification. |
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Correlational selection and genetic architecture promote the leaf economics spectrum in a perennial grass |
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Movement ecology of vulnerable lowland tapirs across a gradient of human disturbance |
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Multi-marker metabarcoding resolves subtle variations in freshwater condition: Bioindicators, ecological traits, and trophic interactions |
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In Silico Prediction and Comparison of Resistomes in Model Pseudomonas Strains by Resistance Gene Identifier (RGI) |
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Repressing PTB is incapable to convert reactive astrocytes to dopaminergic neurons in a mouse model of Parkinson's disease |
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Rapid reconstruction of neural circuits using tissue expansion and lattice light sheet microscopy |
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Insightful inference compensates for distorted perception |
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Mapping of individual sensory nerve axons from digits to spinal cord with the Transparent Embedding Solvent System |
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Multiplexed Cell-Based Diagnostic Devices for Detection of Renal Biomarkers Using Genetic Circuits |
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Reconstruction of sound driven, actively amplified and spontaneous motions within the tree cricket auditory organ |
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Multi-Branch-CNN: classification of ion channel interacting peptides using parallel convolutional neural networks |
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Contrastive learning on protein embeddings enlightens midnight zone at lightning speed |
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Volumetric Tomographic 3D Bioprinting of Heterocellular Bone-like Tissues in Seconds |
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Deep Learning-based Automated Rare Sperm Identification from Testes Biopsies |
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Patterns of regulatory divergence and gene expression in hybrids are associated with molecular evolution in species undergoing gene flow |
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Large-scale algorithmic search identifies stiff and sloppy dimensions in synaptic architectures consistent with murine neocortical wiring |
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Hypnosis Measuring: The Pilot Study of Machine Learning Approach for Instrumental Control of the Trance Dynamics in Patients with Anxiety and Depressive Disorders |
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Cortical-subcortical structural connections support transcranial magnetic stimulation engagement of the amygdala |
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Sensory processing sensitivity and axonal microarchitecture: Identifying brain structural characteristics for behavior |
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#PeerReview from @eLife of ???????? {micro}-Theraphotoxin-Pn3a inhibition of Cav3.3 channels reveals a novel isoform-selective drug binding site |
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#PeerReview from @eLife of ???????? The molecular mechanism of load adaptation by branched actin networks |
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Vγ usage distinguishes pro- and anti-tumor intestinal γδ T cell subsets |
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Age-linked suppression of lipoxin A4 mediates cognitive deficits in mice and humans |
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Homology mediated end joining enables efficient non-viral targeted integration of large DNA templates in primary human T cells |
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Siderophores as an iron source for Prochlorococcus in deep chlorophyll maximum layers of the oligotrophic ocean |
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Poly ADP-ribosylation of SET8 leads to aberrant H4K20me1 domains in mammalian cells |
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The Transcriptome Architecture of Polyomaviruses |
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Progressive enhancement of kinetic proofreading in T cell antigen discrimination from receptor activation to DAG generation |
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Cryo-EM structure of the Inner Ring from Xenopus laevis Nuclear Pore Complex |
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A new approach to the determination of tubular membrane capacitance: passive membrane electrical properties under reduced electrical conductivity of the extracellular solution |
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Inhibition of Interactions Between NDPK-B and NDPK-C in Presence of Graphene Oxide |
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Timelapse viability assay to detect division and death of primary multiple myeloma cells in response to drug treatments with single cell resolution |
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Persistent parental RNAi in the beetle Tribolium castaneum involves maternal transmission of long double-stranded RNA |
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Stage-specific disruption of X chromosome expression during spermatogenesis in sterile house mouse hybrids |
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A quantitative synthesis of soil microbial effects on plant species coexistence |
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A Multi-Omics and Bioenergetics Longitudinal Aging Dataset in Primary Human Fibroblasts with Mitochondrial Perturbations |
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A novel mechanism of bulk cytoplasmic transport by cortical dynein in Drosophila ovary |
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Three-dimensional structure of the kinetochore-fibers in human mitotic spindles |
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Recombinant Group A Carbohydrate backbone embedded into Outer Membrane Vesicles is a potent vaccine candidate targeting Group A Streptococcus from Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis |
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Ferric Citrate Uptake is a Virulence Factor in Uropathogenic Escherichia coli |
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FoxP3 associates with enhancer-promoter loopsto regulate Treg-specific gene expression |
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Protection of mice against experimental cryptococcosis by synthesized peptides delivered in glucan particles |
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Uncovering natural variation in root system architecture and growth dynamics using a robotics-assisted phenomics platform |
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Precision size and refractive index analysis of weakly scattering nanoparticles in polydispersions. |
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A New Approach to Testing Mediation of the Microbiome using the LDM |
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Site-Specific Synthesis of N4-Acetylcytidine in RNA Reveals Physiological Duplex Stabilization |
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Molecular basis for the regulation of human glycogen synthase by phosphorylation and glucose-6-phosphate |
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hNOP2/NSUN1 Regulates Ribosome Biogenesis through Stabilization of snoRNP Complexes and Cytosine-5 Methylation of 28S rRNA. |
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The Stickland fermentation precursor trans-4-hydroxyproline differentially impacts the metabolism of Clostridioides difficile and commensal Clostridia |
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New neurons in old brains: A cautionary tale for the analysis of neurogenesis in post-mortem tissue. |
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Reliable population utility signal from diverse economic value coding in orbitofrontal neurons |
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Maternal diet disrupts the placenta-brain axis in a sex-specific manner |
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Genome-wide alignment-free phylogenetic distance estimation under a no strand-bias model |
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Determinants of precocious B-cell aging in European adolescences living with perinatally acquired HIV-1 after over 10 years of suppressive therapy |
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Higher-order interaction of brain microstructural and functional connectome |
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The BCM rule allows a spinal cord model to learn rhythmic movements |
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smBEVO: A computer vision approach to rapid baseline correction of single-molecule time series |
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CarboGrove: a resource of glycan-binding specificities through analyzed glycan-array datasets from all platforms |
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A modular and reusable model of epithelial transport in the proximal convoluted tubule |
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Genetic regulation of RNA splicing in human pancreatic islets |
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Gattaca: Base pair resolution mutation tracking for somatic evolution studies using agent-based models |
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Pangenome evolution in environmentally transmitted symbionts of deep-sea mussels is governed by vertical inheritance |
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Fish diversity drives regional productivity but not stability in southeastern United States coastal marine fishes |
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Rapid and efficient generation of antigen-specific isogenic T cells from cryopreserved blood samples |
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The overlapping modular organization of human brain functional networks across the adult lifespan |
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Therapeutic Deep Brain Stimulation Disrupts Subthalamic Nucleus Activity Dynamics in Parkinsonian Mice |
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Neurotransmission and neuromodulation systems in the learning and memory network of Octopus vulgaris |
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Electrical Stimulated Glut4 Signaling Attenuates Critical Illness-Associated Muscle Wasting |
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An end-to-end workflow for multiplexed image processing and analysis |
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HMD-AMP: Protein Language-Powered Hierarchical Multi-label Deep Forest for Annotating Antimicrobial Peptides |
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GEDI: an R package for integration of transcriptomic data from multiple high-throughput platforms |
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AgAnt: A computational tool to assess Agonist/Antagonist mode of interaction |
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Modeling chromatin state from sequence across angiosperms using recurrent convolutional neural networks |
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Neophobia and innovation in critically endangered Bali myna, Leucopsar rothschildi |
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Probability weighting explains Independence Axiom violations of Expected Utility Theory in monkeys |
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networkGWAS: A network-based approach for genome-wide association studies in structured populations |
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Haplotype-aware single-cell multiomics uncovers functional effects of somatic structural variation |
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WormCat 2.0 defines characteristics and conservation of poorly annotated genes in Caenorhabditis elegans |
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A novel method to identify cell-type specific regulatory variants and their role in cancer risk |
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Wnt5A Signaling Blocks Progression of Experimental Visceral Leishmaniasis |
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Zika virus infection during development impairs the formation of corpus callosum by disturbing axon guidance and growth of callosal neurons. |
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Resting-state functional connectivity of social brain regions predicts motivated dishonesty |
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Recurrent neural circuits overcome partial inactivation by compensation and re-learning |
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Synaptic Self-Organization of Spatio-Temporal Pattern Selectivity |
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Cerebral blood flow predicts multiple demand network activity and fluid intelligence across the lifespan |
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Integrated resource for functional and structural connectivity of the marmoset brain |
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Real-time Image Denoising of Mixed Poisson-Gaussian Noise in Fluorescence Microscopy Images using ImageJ |
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Microglial phagocytosis dysfunction during stroke is prevented by rapamycin |
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Genomic hallmarks of cellular dormancy in cancer and therapeutic implications |
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Identification and Characterization of Long Non-Coding RNA in Tomato Roots under Salt Stress |
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Ab initio modelling of an essential mammalian protein: Transcription Termination Factor 1 (TTF1) |
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The Xenopus Phenotype Ontology: bridging model organism phenotype data to human health and development. |
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FLASHIda: Intelligent data acquisition for top-down proteomics that doubles proteoform level identification count |
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Deeplearning based MHC epitope prediction for cancer neoantigen discovery |
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Three-dimensional Shear Wave Elastography Using a 2D Row Column Addressing (RCA) Array |
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A semantics, energy-based approach to automate biomodel composition |
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Design and execution of a Verification, Validation, and Uncertainty Quantification plan for a numerical model of left ventricular flow after LVAD implantation |
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Three-dimensional Multicolor Subcellular Imaging by Fast Serial Sectioning Tomography for Centimeter-scale Specimens |
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A Multigraph model of the 3D genome |
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Genomic analysis based on chromosome-level genome assembly reveals an expansion of terpene biosynthesis of Azadirachta indica |
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An optimized ChIP-Seq framework for profiling of histone modifications in Chromochloris zofingiensis |
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Mothers front-load their investment to the egg stage when helped in a wild cooperative bird |
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Molecular Evolutionary Analyses of Tooth Genes Support Sequential Loss of Enamel and Teeth in Baleen Whales (Mysticeti) |
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Community composition of coral associated Symbiodiniaceae is driven by fine scale environmental gradients |
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Allelopathic effects of Epichloë fungal endophytes: experiment and meta-analysis |
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Biocatalytic quantification of α-glucan in particulate marine organic matter |
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Data-Poor Ecological Risk Assessment of Multiple Stressors |
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T cells discriminate between groups C1 and C2 HLA-C |
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Subiculum - BNST Structural Connectivity in Humans and Macaques |
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An evaluation of resonant scanning as a high-speed imaging technique for two-photon imaging of cortical vasculature |
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Dopamine depletion can be predicted by the aperiodic component of subthalamic local field potentials |
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Structural brain connectivity predicts acute pain after mild traumatic brain injury |
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Diverse roles of MeCP2 in the specification and maintenance of midbrain dopamine phenotype. |
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α-Synuclein pre-formed fibrils induce prion-like protein aggregation and neurotoxicity in C. elegans models of Parkinson's disease |
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A dynamic clamp protocol to artificially modify cell capacitance |
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Modulation of gamma spectral amplitude and connectivity during reaching predicts peak velocity and movement duration |
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Ca2+ activity is required for injury-induced migration of microglia |
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The use of principal component analysis to measure fundamental cognitive processes in neuropsychological data |
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Generalized harmonic analysis reveals a frequency modulated timer regulates mammalian hibernation |
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Secure Federated Aggregate-Count Queries on Medical Patient Databases Using Fully-Homomorphic Cryptography |
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A Landmark-based Common Coordinate Framework for Spatial Transcriptomics Data |
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Shine: To explore specific, sensitive and conserved biomarkers from massive microbial genomic data within intrapopulations. |
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High-sensitivity pattern discovery in large, paired multi-omic datasets |
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Interactive Analysis of Biosurfactants in Fruit-Waste Fermentation Samples using BioSurfDB and MEGAN |
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Assembly of complete diploid phased chromosomes from draft genome sequences |
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FEASIBILITY OF VASCULAR REMODELING PARAMETER ESTIMATION FOR ASSESSING HYPERTENSIVE PREGNANCY DISORDERS |
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Autonomous treatment of bacterial infections in vivo using antimicrobial micro- and nanomachines |
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3-dimensional arenas for the assessment of C. elegans behavior |
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Low frequency somatic copy number alterations in normal human lymphocytes revealed by large scale single-cell whole genome profiling |
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Little heterosis found in Diploid Hybrid Potato |
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The structural determinants of intra-protein compensatory substitutions |
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Real-time alerts from AI-enabled camera traps using the Iridium satellite network: a case-study in Gabon, Central Africa |
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A series of terribly unfortunate events: How environment and infection synergized to cause the Kihansi spray toad extinction |
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Urbanization and altitude impact on gut microbiome of an Andean frog (Pristimantis unistrigatus) |
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Stromal remodeling regulates dendritic cell abundance and activity in the tumor microenvironment |
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Altered brain criticality in Schizophrenia: New insights from MEG |
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Molecular, anatomical, and functional organization of lung interoceptors |
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PatchWarp: Corrections of non-uniform image distortions in two-photon calcium imaging data by patchwork affine transformations |
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Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease |
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Optogenetic induction of appetitive and aversive taste memories in Drosophila |
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Genome Compartmentalization with Nuclear Landmarks: Random yet Precise |
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Mechanistic insights into the enhancement or inhibition of phase separation by polyubiquitin chains of different lengths or linkages |
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Key Factors Governing Initial Stages of Lipid Droplet Formation |
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The dorsal visual pathway represents object-centered spatial relations for object recognition |
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Cortical wiring by synapse-specific control of local protein synthesis |
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Transcriptional regulation of neonatal neural stem cells is a determinant of social behavior |
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'Constituent length' effects in fMRI do not provide evidence for abstract syntactic processing |
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Biosorption potential and molecular characterization of metal resistant autochthonous microbes from tannery solid waste |
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A two-phase plant-soil feedback experiment to explore biotic influences on Phragmites australis invasion in North American wetlands |
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#PeerReview from @EMBOPress of ???????? Acyl chain shortening induced by inhibition of acetyl-CoA carboxylase renders phosphatidylcholine redundant |
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Total virome characterizations of game animals in China reveals a spectrum of emerging viral pathogens |
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MicNet Toolbox: visualizing and deconstructing a microbial network |
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Individual exploration and selective social learning: Balancing exploration-exploitation trade-offs in collective foraging |
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Whole transcriptome sequencing reveals drought resistance-related genes in upland cotton |
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GutMicroNet: an interactive platform for gut microbiome interaction exploration |
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Similarities Between Somatosensory Cortical Responses Induced via Natural Touch and Microstimulation in the Ventral Posterior Lateral Thalamus in Macaques |
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Effective Cell Membrane Tension is Independent of Substrate Stiffness |
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Toeholder: a software for automated design and in silico validation of toehold riboswitches |
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Acoustic and postural displays in a miniature and transparent teleost fish, Danionella dracula |
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Long-term evolution of quantitative traits in the Drosophila melanogaster species subgroup |
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Genome-wide selection signatures reveal widespread synergistic effects of culture conditions and temperature stress in Drosophila melanogaster |
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Foraging behavior and patch size distribution jointly determine population dynamics in fragmented landscapes |
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Notch-dependent DNA cis-regulatory elements and their dose-dependent control of C. elegans stem cell self-renewal |
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Integration of vascular progenitors into functional blood vessels represents a novel mechanism of vascular growth |
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Base editing in bovine embryos reveals a species-specific role of SOX2 in regulation of pluripotency |
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Human Sex Matters: Y-linked lysine demethylase 5D drives accelerated male osteogenic differentiation |
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Sonic hedgehog is basolaterally sorted from the TGN and transcytosed to the apical domain involving Dispatched-1 at Rab11-ARE |
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Trisomy 21 induces pericentrosomal crowding disrupting early stages of primary ciliogenesis and mouse cerebellar development |
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Persistent CAD activity in memory CD8+ T cells supports rRNA synthesis and ribosomal biogenesis required at rechallenge |
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A vaccine targeting the L9 epitope of the malaria circumsporozoite protein confers protection from blood-stage infection in a mouse challenge model |
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Contribution of linear and nonlinear mechanisms to predictive motion estimation |
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An Infant Sleep Electroencephalographic Marker of Thalamocortical Connectivity Predicts Behavioral Outcome in Late Infancy |
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IFN-γ stimulated murine and human neurons mount anti-parasitic defenses against the intracellular parasite Toxoplasma gondii |
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An essential role for a discrete parasubthalamic nucleus subpopulation in appetite suppression |
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Realistic alpha oscillations and transient responses in a cortical microcircuit model |
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Sequence learning attenuates cortical responses in both frontal and perceptual cortices in early infancy |
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Neuroplastin genetically interacts with Cadherin 23 and the encoded isoform Np55 is sufficient for cochlear hair cell function and hearing |
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High-frequency changes in single-trial visual evoked potentials for unattended stimuli in chronic schizophrenia |
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Biophysical and Architectural Mechanisms of Subthalamic Theta under Response Conflict |
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Microlitter pollution in the marine environment and preliminary evidences of in vitro cytotoxic effects on two Mediterranean commercial fish species |
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Non-canonical Function of a Hif-1α Splice Variant Contributes to the Sustained Flight of Locusts |
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Attractor Landscapes as a Model Selection Criterion in Data Poor Environments |
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Cell Wall Biochemistry Drives Pollen Tube Mechanics and Affects Growth Rate |
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A synthetic distributed genetic multi-bit counter |
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Children's Species Literacy as Estimated and Desired by Biodiversity Communicators: a Mismatch with the Actual Level |
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Quantitative effects of environmental variation on stomatal anatomy and gas exchange in a grass model |
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Mitigation of Injury from Myocardial Infarction by TH1834, an Inhibitor of the Acetyltransferase Tip60 |
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An in vivo drug repurposing screen and transcriptional analyses reveals the serotonin pathway and GSK3 as major therapeutic targets for NGLY1 deficiency |
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A graph neural network approach to molecule carcinogenicity prediction |
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Conditional Generative Modeling for De Novo Protein Design with Hierarchical Functions |
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Improving Neural Networks for Genotype-Phenotype Prediction Using Published Summary Statistics |
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ODGI: understanding pangenome graphs |
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Chromosome scale assembly of allopolyploid genome of the diatom Fistulifera solaris |
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Divergent phenotypic plasticity of a convergent Mendelian trait in Drosophila |
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Transgenerational impact of aberrant inflammation in rat pregnancy |
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Pluripotency-Independent Induction of Human Trophoblast Stem Cells from Fibroblasts |
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Club cells are the primary source of pIgR in small airways |
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The roles of distinct Ca2+ signaling mediated by Piezo and inositol triphosphate receptor (IP3R) in the remodeling of E-cadherin during cell dissemination |
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Robust and unbiased estimation of the background distribution for automated quantitative imaging |
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8 A structure of the nuclear ring of the Xenopus laevis nuclear pore complex solved by cryo-EM and AI |
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Determining the architecture of nuclear ring of Xenopus laevis nuclear pore complex using integrated approaches |
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8 A structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex solved by cryo-EM and AI |
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Increased frequency of CD4+ and CD8+ follicular helper T cells in human lymph node biopsies during the earliest stages of rheumatoid arthritis |
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Prehension kinematics in humans and macaques |
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Age-dependent formation of TMEM106B amyloid filaments in human brain |
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Structural Basis for pH-Gating of the K+ Channel TWIK1 at the Selectivity Filter |
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Audiovisual task switching rapidly modulates sound encoding in mouse auditory cortex |
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Functional but not obligatory link between microsaccades and neural modulation by covert spatial attention |
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Cortico-striatal activity characterizes human safety learning via Pavlovian conditioned inhibition |
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Depth-targeted intracortical microstroke by two-photon photothrombosis in rodent brain |
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Neurons derived from individual early Alzheimer's disease patients reflect clinical vulnerability |
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Semantic relation priming is not constituent-specific: Evidence from ERP |
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NIfTI-MRS: A standard format for magnetic resonance spectroscopic data |
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What happened when? Brain and behavioral responses to violated expectations about the structure and content of episodic memories |
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Lipophorin receptors regulate mushroom bodies development and participate in learning, memory, and sleep in flies |
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Necroptosis inhibition counteracts axonal degeneration, cognitive decline and key hallmarks of aging, promoting brain rejuvenation. |
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Reliability of quantitative multiparameter maps is high for MT and PD but attenuated for R1 and R2* in healthy young adults |
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Real-time computation of transcranial magnetic stimulation electric fields using self-supervised deep learning |
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Real-time motion monitoring improves functional MRI data quality in infants |
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Photochemical pre-bleaching of formalin-fixed archival prostate tissues significantly reduces autofluorescence to facilitate multiplex immunofluorescence staining |
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DNA Self-Assembled Plasmonic Nanodiamonds for Biological Sensing |
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Resonant Learning in Scale-free Networks |
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The Role of Extended Range of Interactions in the Dynamics of Interacting Molecular Motors |
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A novel cryo-electron microscopy support film based on 2D crystal of HFBI protein |
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A Machine Learning Approach to Identify Specific Small Molecule Inhibitors of Secondary Nucleation in alpha-Synuclein Aggregation |
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A small molecule stabilises the disordered native state of the Alzheimer's Aβ peptide |
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scHiCSRS: A Self-Representation Smoothing Method with Gaussian Mixture Model for Imputing single-cell Hi-C Data |
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Robust and generalizable segmentation of human functional tissue units |
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From shallow to deep: exploiting feature-based classifiers for domain adaptation in semantic segmentation |
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Unsupervised integration of single-cell multi-omics datasets with disparities in cell-type representation |
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Deciphering the language of antibodies using self-supervised learning |
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Scalable estimation of microbial co-occurrence networks with Variational Autoencoders |
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Lossless Indexing with Counting de Bruijn Graphs |
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Jointly leveraging spatial transcriptomics and deep learning models for pathology image annotation improves cell type identification over either approach alone. |
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Weakly-Supervised Tumor Purity Prediction FromFrozen H&E Stained Slides |
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Predicting direct physical interactions in multimeric proteins with deep learning |
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Imaging the Extent and Location of Spatiotemporally Distributed Epileptiform Sources from MEG Measurements |
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Characterization of scar tissue biomechanics during adult murine flexor tendon healing |
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A Transparent Ultrasound Array for Real-time Optical, Ultrasound and Photoacoustic Imaging |
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Effects of tendon viscoelasticity in the distribution of forces over sutures in a model tendon-to-bone repair |
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FLIP: Benchmark tasks in fitness landscape inference for proteins |
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Fast anther dehiscence state recognition system establishing by deep learning to screen heat tolerant cotton |
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SARS-CoV-2 ORF8 encoded protein contains a histone mimic, disrupts chromatin regulation, and enhances replication |
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Physiological and life history changes associated with seasonal adaptation in the cactophilic Drosophila mojavensis |
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Disentangling the effects of jasmonate and tissue loss on the sex allocation of an annual plant |
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Transcriptome innovations in primates revealed by single-molecule long-read sequencing |
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A theoretical framework for multi-species range expansion in spatially heterogeneous landscapes |
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Tropical forest dynamics correspond to fair games in economic theory of financial markets |
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Large cells activate global protein degradation to maintain cell size homeostasis |
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The C. elegans TspanC8 tetraspanin TSP-14 exhibits isoform-specific localization and function |
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A myosin chaperone, UNC-45A, is a novel regulator of intestinal epithelial barrier integrity and repair |
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Clinically relevant SMAC mimetics do not enhance human T cell proliferation or cytokine production |
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Fascicles split or merge every ~560 microns within the human cervical vagus nerve |
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Control of cortical cytoskeleton-membrane interaction by RhoA regulates peripheral nerve myelination |
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Compositional Restricted Boltzmann Machines Unveil the Brain-Wide Organization of Neural Assemblies |
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Identification of mRNAs that undergo stop codon readthrough in Arabidopsis thaliana |
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Solanum galapagense-derived purple tomato fruit color is conferred by novel alleles of the Anthocyanin fruit and atroviolacium loci |
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Combining dictionary- and rule-based approximate entity linking with tuned BioBERT |
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Learning enhances behaviorally relevant representations in apical dendrites |
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Heterogeneous CaMKII-dependent synaptic compensations in CA1 pyramidal neurons from acute slices with dissected CA3 |
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Accurate inference of stochastic gene expression from nascent transcript heterogeneity |
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Quantitative isotope-labeled crosslinker proteomics reveals developmental variation in protein interactions and posttranslational modifications in Diaphorina citri, the citrus greening insect vector |
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Estimating the rates of crossover and gene conversion from individual genomes |
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Measuring the invisible - The sequences causal of genome size differences in eyebrights (Euphrasia) revealed by k-mers |
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B cell clonal expansion is correlated with antigen-specificity in young but not old mice |
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A novel machine learning-based approach for the detection and analysis of spontaneous synaptic currents |
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Sensitivity optimization of a rhodopsin-based fluorescent voltage indicator |
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Measuring metabolic rate in single flies during sleep and waking states |
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Cortical and autonomic responses during staged Taoist meditation: two distinct meditation strategies. |
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REDigest: a Python GUI for In-Silico Restriction Digestion Analysis of Genes or Complete Genome Sequences |
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Once-daily feeding is associated with better cognitive function and health in companion dogs: Results from the Dog Aging Project |
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Deamidated TPI is an efficacious target for cell-selective therapy in triple-negative breast cancer |
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#PeerReview from @eLife of ???????? Rap1, Rif2, and the Ku complex work in concert to cap chromosome ends |
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The genetic diversity of Ethiopian barley genotypes in relation to their geographical origin |
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A platform of patient-derived microtumors identifies treatment response and therapeutic vulnerabilities of ovarian cancer |
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VALIS: Virtual Alignment of pathoLogy Image Series |
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Efficient multi-gene expression in cell-free droplet microreactors |
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Alterations in the Antioxidant Metabolites in Cotton Leaf Curl Disease Infected and Healthy Cotton Leaves |
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Biological integrity enhances the qualitative effectiveness of conditional mice-oak mutualisms |
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#PeerReview from @EMBOPress of ???????? Modulation of root growth by nutrient-defined fine-tuning of polar auxin transport |
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Pre- and post-mating reproductive isolation evolve independently during rapid adaptation to high temperature |
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Closely-related tree species with overlapping ranges exhibit divergent adaptation to climate |
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Evidence for a long-r ange RNA-RNA interaction between ORF8 and the downstream region of the Spike polybasic insertion of SARS-CoV-2 |
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A new prognostic model for pancreatic cancer based on pyroptosis-related genes |
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Salmonella Outer Membrane Vesicles contain tRNA Fragments (tRFs) that Inhibit Bacteriophage P22 infection |
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Platelets are dispensable for the ability of CD8+ T cells to accumulate, patrol, kill and reside in the liver |
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Pictorial balance is a bottom-up aesthetic property mediated by eye movements |
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Structure-Activity Relationships in the Design of Mitochondria-Targeted Peptide Therapeutics |
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The evolutionary dynamics of genetic mutational load throughout tomato domestication history |
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Sequestration of LINE-1 in novel cytosolic bodies by MOV10 restricts retrotransposition |
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Spatial relationships of intra-lesion heterogeneity in Mycobacterium tuberculosis microenvironment, replication status, and drug efficacy |
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NorA, HmpX, and NorB cooperate to reduce NO toxicity during denitrification and plant pathogenesis in Ralstonia solanacearum |
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Host-associated phages disperse across the extraterrestrial analogue Antarctica |
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Nuclear receptor subfamily 4A signaling as a key disease pathway of CD1c+ dendritic cell dysregulation in systemic sclerosis |
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Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43 |
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PccGEO: prior constraints conditioned genetic elements optimization |
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ICOR: Improving codon optimization with recurrent neural networks |
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Improvement of muscle strength in a mouse model for congenital myopathy treated with HDAC and DNA methyltransferase inhibitors |
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Glomerular function and urinary biomarker changes between vancomycin and vancomycin plus piperacillin-tazobactam in a translational rat model. |
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Data independent acquisition enables deep and fast label-free dynamic organellar mapping |
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Assessing and enhancing foldability in designed proteins |
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Coordinated conformational changes in the V1 complex during V-ATPase reversible dissociation |
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Pentameric assembly of the Kv2.1 tetramerization domain. |
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Natural variation in gene expression and Zika virus susceptibility revealed by villages of neural progenitor cells |
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Large-scale identification of RBP-RNA interactions by RAPseq refines essentials of post-transcriptional gene regulation |
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Novel genetic basis of resistance to Bt toxin Cry1Ac in Helicoverpa zea |
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Mitochondria transplantation between living cells |
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Water column stability as an important factor controlling nitrite-dependent anaerobic methane oxidation in stratified lake basins |
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Factors Influencing the Detection of Antibacterial Resistant Escherichia coli in Faecal Samples from Individual Cattle |
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Nitric Oxide Attenuates Human Cytomegalovirus Infection yet Disrupts Neural Cell Differentiation and Tissue Organization |
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PRMT5 epigenetically regulates the E3 ubiquitin ligase ITCH to influence lipid accumulation during mycobacterial infection |
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LuxT is a Global Regulator of Low-Cell Density Behaviors Including Type III Secretion, Siderophore Production, and Aerolysin Secretion in Vibrio harveyi |
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A self-amplifying mRNA COVID-19 vaccine drives potent and broad immune responses at low doses that protects non-human primates against SARS-CoV-2 |
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F1F0 ATP Hydrolysis is a Determinant of Metabolic Rate and a Correlate of Lifespan |
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Phage-like particle vaccines are highly immunogenic and protect against pathogenic coronavirus infection and disease |
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SARS-CoV-2 triggered excessive inflammation and abnormal energy metabolism in gut microbiota |
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Towards a structurally resolved human protein interaction network |
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CRISPR-Cas9 mediated nuclear transport and genomic integration of nanostructured genes in human primary cells |
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#PeerReview from @eLife of ???????? Functional diversification gave rise to allelic specialization in a rice NLR immune receptor pair |
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The Escherichia coli serS gene promoter region overlaps with the rarA gene |
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An interactome landscape of SARS-CoV-2 virus-human protein-protein interactions by protein sequence-based multi-label classifiers |
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Central and peripheral delivery of AAV9-SMN target different pathomechanisms in a mouse model of spinal muscular atrophy |
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Microbial signals and lymphotoxin drive TNF-independent death of A20 and ABIN-1 deficient epithelium |
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High Throughput Intact Protein Analysis Using Infrared Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry |
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Ciliary Generation of a Peptidergic Sexual Signal |
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The bacterial actin-like cell division protein FtsA forms curved antiparallel double filaments upon binding of FtsN |
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Fast and sensitive GCaMP calcium indicators for imaging neural populations |
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Inversely proportional myelin growth due to altered Pmp22 gene dosage identifies PI3K/Akt/mTOR signaling as a novel therapeutic target in HNPP |
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Distribution And Population Of Chukar Partrigde (Alectoris chukar) In District Bajuar, KPK, Pakistan |
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A reaction-diffusion model predicts the intracellular length scale over which EGFR-initiated GAB1-SHP2 complexes persist |
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New insights into the evolution of glutamine synthetase isoenzymes in plants |
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Loss of function of bHLH transcription factor Nrd1 in tomato induces an arabinogalactan protein-encoding gene and enhances resistance to Pseudomonas syringae pv. tomato |
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Macrophage proliferation machinery leads to PDAC progression, but susceptibility to innate immunotherapy. |
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Prostate tumor-induced stromal reprogramming generates Tenascin C that promotes prostate cancer metastasis through YAP/TAZ inhibition |
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Transcription modulates chromatin dynamics and locus configuration sampling |
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Accelerating in-silico saturation mutagenesis using compressed sensing |
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A multiscale computational study of the conformation of the full-length intrinsically disordered protein MeCP2 |
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INDUCED MUTATIONS IN TaASN-A2 REDUCE FREE ASPARAGINE CONCENTRATION IN THE WHEAT GRAIN |
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Prevalent mouse phenotypes in the unexplored druggable genome |
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Lack of Fe(II) transporters in basal Cyanobacteria complicates iron uptake in ferruginous Archean oceans. |
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The C. elegans gonadal sheath Sh1 cells associate selectively with a differentiating germ cell population in the proliferative zone |
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Molecular signature of postmortem lung tissue from COVID-19 patients suggests distinct trajectories driving mortality |
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Lagging strand gap suppression connects BRCA-mediated fork protection to nucleosome assembly by ensuring PCNA-dependent CAF-1 recycling |
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SARS-COV-2 Delta variant displays moderate resistance to neutralizing antibodies and spike protein properties of higher soluble ACE2 sensitivity, enhanced cleavage and fusogenic activity |
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Paradoxical excitation of lateral habenula neurons by propofol involves enhanced presynaptic release of glutamate |
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Epidermal Growth Factor Receptor Inhibition Prevents Caveolin-1-dependent Calcifying Extracellular Vesicle Biogenesis |
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Oncogenic and Tumor Suppressor Functions for Lymphoid Enhancer Factor 1 in a Murine Model of T Acute Lymphoblastic Leukemia |
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Structural basis of main proteases of coronavirus bound to drug candidate PF-07321332 |
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Predicting Relative Protein Abundance via Sequence-Based Information |
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In vitro reconstitution of divisome activation |
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A chemical screen for suppressors of dioxygenase inhibition in a yeast model of familial paraganglioma |
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Accelerated decline of genome heterogeneity in the SARS-CoV-2 coronavirus |
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Transcriptome analysis of Plasmodium falciparum isolates from Benin reveals specific gene expression associated with cerebral malaria |
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The molecular evolution of spermatogenesis across mammals |
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Interchromosomal interaction of homologous Stat92E alleles regulates transcriptional switch during stem-cell differentiation |
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Ribosomal ubiquitination facilitates mRNA cleavage and ribosome rescue during No-Go and Nonstop mRNA Decay |
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Brain Networks Detectable by fMRI during On-Line Self Report of Hallucinations in Schizophrenia |
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The learning curve of murine subretinal injection among clinically trained ophthalmic surgeons |
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The Immune Signatures Data Resource: A compendium of systems vaccinology datasets |
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Open Access publishing in Medicine: lights and shadows. |
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Lipid Alterations in African American Prostate Cancer |
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A connectivity signature for glioblastoma |
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Block aligner: fast and flexible pairwise sequence alignment with SIMD-accelerated adaptive blocks |
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Genetic continuity of Indo-Iranian speakers since the Iron Age in southern Central Asia. |
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Lipid nanoparticles incorporating a GalNAc ligand enable in vivo liver ANGPTL3 editing in wild-type and somatic LDLR knockout non-human primates |
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A simple and general approach to control the activity of DNA processing enzymes |
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A full-length infectious cDNA clone of a dsRNA totivirus-like virus |
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Recurrent urinary tract infection and estrogen shape the taxonomic ecology and functional potential of the postmenopausal urobiome |
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A comparative analysis of memory B cell and antibody responses against Plasmodium falciparum merozoite surface protein 1 in children and adults from Uganda |
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ACPA-IgG variable domain glycosylation increases before the onset of rheumatoid arthritis and stabilizes thereafter; a cross-sectional study encompassing over 1500 samples |
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Feasibility evaluation of transtympanic laser stimulation of the cochlea from the outer ear |
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Sexual dimorphic responses of C57BL/6 mice to Fisetin or Dasatinib and Quercetin cocktail oral treatment |
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Nuclear progesterone receptor regulates blood coagulation facilitating ovulation in zebrafish |
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The anterior cruciate ligament in murine post-traumatic osteoarthritis: markers and mechanics |
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DOCKGROUND Membrane Protein-Protein Set |
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Identification of known and novel long non-coding RNAs potentially responsible for the effects of BMD GWAS loci |
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From group to individual - Genotyping by pool sequencing eusocial colonies |
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Krüppel-like factor 4 is required for development and regeneration of germline and yolk cells from somatic stem cells in planarians |
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ATM-dependent formation of a novel chromatin compartment regulates the Response to DNA Double Strand Breaks and the biogenesis of translocations |
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Stable Cell Clones Harboring Self-Replicating SARS-CoV-2 RNAs for Drug Screen |
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Modelling novelty detection in the thalamocortical loop |
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Generation of a mitochondrial protein compendium in Dictyostelium discoideum |
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BBX16 mediates the repression of seedling photomorphogenesis downstream of the GUN1-GLK1 module during retrograde signaling |
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Dosage of duplicated and antifunctionalized homeobox proteins influences spikelet development in barley |
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Disassembly of hemidesmosomes promotes tumorigenesis in PTEN-negative prostate cancer by targeting plectin into focal adhesions |
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Enhanced fluorescence from semiconductor quantum dot-labelled cells excited at 280 nm |
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From the origin and molecular diversity of the amastins, to the origin and diversity of intracellular parasitism from human Trypanosomatids |
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Electrical signature of heterogeneous human mesenchymal stem cells |
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Light contamination in stable isotope-labelled internal peptide standards is frequent and a potential source of false discovery and quantitation error in proteomics |
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Structural insights into the activation of autoinhibited human lipid flippase ATP8B1 upon substrate binding |
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Phase of neural oscillations as a reference frame for attention-based routing in visual cortex |
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#PeerReview from @PeerCommunityIn of ???????? Dynamics of sex-biased gene expression over development in the stick insect Timema californicum |
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#PeerReview from @eLife of ???????? Control of neurotransmitter release and presynaptic plasticity by re-orientation of membrane-bound Munc13-1 |
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#PeerReview from @ReviewCommons of ???????? DynaMorph: learning morphodynamic states of human cells with live imaging and sc-RNAseq |
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Land use land cover dynamics through time and their proximate drivers of change in a tropical mountain system: a case study in a highland landscape of northern Ecuador |
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ANI, Mash and Dashing equally differentiate between Klebsiella species |
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Deep time structural evolution of retroviral and filoviral surface envelope proteins |
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Distinct profiles of LRRK2 activation and Rab GTPase phosphorylation in clinical samples from different PD cohorts |
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A high-throughput, automated, cell-free expression and screening platform for antibody discovery |
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ProDCoNN-server: a web server for protein sequence prediction and design from a three-dimensional structure |
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Affinity sedimentation and magnetic separation with plant-made immunosorbent nanoparticles for therapeutic protein purification |
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Discovery of a carbonic anhydrase-Rubisco supercomplex within the alpha-carboxysome |
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Ancient genomes from the last three millennia support multiple human dispersals into Wallacea |
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Ubiquitin ligases and a processive proteasome facilitate protein clearance during the oocyte-to-embryo transition in Caenorhabditis elegans |
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Age-induced P-bodies become detrimental and shorten the lifespan of yeast |
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Antibiofilm agents with therapeutic potential against enteroaggregative Escherichia coli |
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Outer Membrane Vesicles from the gut microbiome contribute to tumor immunity by eliciting cross-reactive T cells |
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Prevalence of bovine tuberculosis and characterization of the members of the Mycobacterium tuberculosis complex from slaughtered cattle in Rwanda |
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Single cell RNA-seq uncovers the nuclear decoy lincRNA PIRAT as a regulator of systemic monocyte immunity during COVID-19 |
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Design, construction and optimization of a synthetic RNA polymerase operon in Escherichia coli. |
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Enteroendocrine cell types that drive food reward and aversion |
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Erythropoietin and miRNA profiles during the menstrual cycle in relation to hematological and lipid biomarkers |
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Validation and invalidation of SARS-CoV-2 papain-like protease inhibitors |
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Brilacidin, a COVID-19 Drug Candidate, demonstrates broad-spectrum antiviral activity against human coronaviruses OC43, 229E and NL63 through targeting both the virus and the host cell |
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Discovery of imidazole-based inhibitors of P. falciparum cGMP-dependent protein kinase |
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Spread of Xanthomonas vasicola pv. musacearum within banana mats: implications for Xanthomonas wilt management |
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Regulation of ERK2 activity by dynamic S-acylation |
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A truncated reverse transcriptase enhances prime editing by split AAV vectors |
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CALDERA: Finding all significant de Bruijn subgraphs for bacterial GWAS |
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Correlation scan: identifying genomic regions that affect genetic correlations applied to fertility traits |
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Mitochondrial DNA variants segregate during human preimplantation development into genetically different cell lineages that are maintained postnatally |
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A novel enhancer of Agouti contributes to parallel evolution of cryptically colored beach mice |
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Identification and characterization of BEND2 as a novel and key regulator of meiosis during mouse spermatogenesis |
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Pharmacologic rescue of circadian β-cell failure through P2Y1 purinergic receptor identified by small-molecule screen |
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SARS-CoV-2 infection in free-ranging white-tailed deer (Odocoileus virginianus) |
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Turnover in life strategies recapitulates microbial succession on synthetic marine particles |
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Scrutiny of human lung infection by SARS-CoV-2 and associated human immune responses in humanized mice |
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Single-Cell RNA Sequencing Characterizes the Molecular Heterogeneity of the Larval Zebrafish Optic Tectum |
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Sexual reproduction contributes to the evolution of resistance breaking isolates of the spinach pathogen Peronospora effusa |
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Sequence conservation, domain architectures, and phylogenetic distribution of the HD-GYP type c-di-GMP phosphodiesterases |
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A novel whole yeast-based subunit oral vaccine against Eimeria tenella in chickens |
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Two new threatened species of Rinorea (Violaceae), forest trees from East and South Regions, Cameroon |
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TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing |
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Stenoparib, an inhibitor of cellular poly (ADP-ribose) polymerases (PARPs), blocks in vitro replication of SARS-CoV-2 variants |
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Increased Occurrence of Treponema spp. and Double-species Infections in Patients with Alzheimer's Disease |
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Prolonged and extended impacts of SARS-CoV-2 on the olfactory neurocircuit |
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Assessment of AI-based Protein Structure Prediction for the NLRP3 Target |
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Towards a Theory of Evolution as Multilevel Learning |
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The oral protease inhibitor (PF-07321332) protects Syrian hamsters against infection with SARS-CoV-2 variants of concern |
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A trimeric NTD and RBD SARS-CoV-2 subunit vaccine induced protective immunity in CAG-hACE2 transgenic mice and rhesus macaques |
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#PeerReview from @eLife of ???????? Microtubule assembly by soluble tau impairs vesicle endocytosis and excitatory neurotransmission via dynamin sequestration in Alzheimer's disease synapse model |
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#PeerReview from @eLife of ???????? Pavlovian fear conditioning does not readily occur in rats in naturalistic environments |
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#PeerReview from @eLife of ???????? Disruption of the TCA cycle reveals an ATF4-dependent integration of redox and amino acid metabolism |
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Behavioral context affects social signal representations within single primate prefrontal cortex neurons |
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Temporal Pattern of Synaptic Activation Determines the Longevity of Structural Plasticity at Single Dendritic Spines |
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Inhibitory Cerebellar Stimulation Increases Cortical Activation: Evidence for Cerebellar Scaffolding of Cortical Processing |
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Epithelial-mesenchymal plasticity induced by discontinuous exposure to TGFβ1 promotes tumour growth |
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Strontium isotopes reveal diverse life history variations, migration patterns, and habitat use for Broad Whitefish (Coregonus nasus) in Arctic, Alaska |
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Programmable large DNA deletion, replacement, integration, and inversion with twin prime editing and site-specific recombinases |
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Dephosphorylation of the pre-initiation complex during S-phase is critical for origin firing |
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Bright, fluorogenic and photostable avidity probes for RNA imaging |
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Marker-free coselection for successive rounds of prime editing in human cells |
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RBBP6 activates the pre-mRNA 3'-end processing machinery in humans |
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A deep exon cryptic splice site promotes aberrant intron retention in a von Willebrand disease patient |
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A critical role for E2-p53 interaction during the human papillomavirus 16 life cycle |
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Loop-extrusion and polymer phase-separation can co-exist at the single-molecule level to shape chromatin folding |
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Xist-mediated silencing requires additive functions of SPEN and Polycomb together with differentiation-dependent recruitment of SmcHD1 |
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mRNA Vaccines Induce Rapid Antibody Responses in Mice |
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Antiviral activity of Pacific oyster (Crassostrea gigas) hemolymph against a human coronavirus. |
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Glycan-masking spike antigen in NTD and RBD elicits broadly neutralizing antibodies against SARS-CoV-2 variants |
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Detection of velogenic avian paramyxoviruses in rock doves in New York City, New York |
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Aryl hydrocarbon receptor (AhR) activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) dose-dependently shifts the gut microbiome consistent with the progression of steatosis to steatohepatitis with fibrosis |
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Creatine utilization as a sole nitrogen source in Pseudomonas putida KT2440 is transcriptionally regulated by CahR |
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Maize AFP1 confers antifungal activity by inhibiting chitin deacetylases from a broad range of fungi |
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JAK-STAT Signaling Enables Lineage Plasticity-driven AR Targeted Therapy Resistance |
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Altered expression of Api5 affects breast carcinogenesis by modulating FGF2 signalling |
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ParS-independent recruitment of the bacterial chromosome-partitioning protein ParB |
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Tau differentially regulates the transport of early endosomes and lysosomes |
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Annexin A4 senses membrane curvature in a density-dependent manner |
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CRISPR-Csx28 forms a Cas13b-activated membrane pore required for robust CRISPR-Cas adaptive immunity |
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The effect of acute oral galactose administration on the redox system of the rat small intestine |
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Reconstitution of ATP-dependent 3'-cleavage of mammalian pre-mRNA reveals a central role of RBBP6 |
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N4BP1 is dimerization-dependent linear ubiquitin reader regulating TNFR1 signalling through linear ubiquitin binding and Caspase-8-mediated processing |
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GapMind for Carbon Sources: Automatedannotations of catabolic pathways |
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Novel Feline Papillomavirus Isolate P20 Assembled from Metagenomic Data Isolated from Human Skin of a House Cat Owner |
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Germinal centre-driven maturation of B cell response to SARS-CoV-2 vaccination |
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A vitamin D-RelB/NF-κB pathway limits Chandipura virus multiplication by rewiring the homeostatic state of autoregulatory type 1 interferon-IRF7 signaling |
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Powerful synergistic effects of a STING agonist and an IL-2 superkine in cancer immunotherapy against MHC I-deficient and MHC I+ tumors |
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Garlic-derived organosulfur compounds regulate metabolic and immune pathways in macrophages and attenuate intestinal inflammation in mice |
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Microglia ferroptosis is prevalent in neurodegenerative disease and regulated by SEC24B |
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Diversity, function and evolution of marine invertebrate genomes |
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Multiple and Dissociable Effects of Sensory History on Working-Memory Performance |
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Effects of upgrading acquisition-techniques and harmonization methods: A multi-modal MRI study with implications for longitudinal designs |
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AAV9-MCT8 delivery at juvenile stage ameliorates neurological and behavioral deficits in an AHDS mouse model |
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Integrating Task-Based Functional MRI Across Tasks Markedly Boosts Prediction and Reliability of Brain-Cognition Relationship |
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The use of Ipratropium and Tiotropium as novel agents to reduce inflammation in in vitro macrophage models. |
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Hepatocyte cholesterol content modulates glucagon receptor signalling |
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Development of Biologically Interpretable Multimodal Deep Learning Model for Cancer Prognosis Prediction |
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Configuring a federated network of real-world patient health data for multimodal deep learning prediction of health outcomes. |
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Investigating the causes of stimulus-evoked changes in cone reflectance using a combined adaptive optics SLO-OCT system |
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Understanding gene regulatory mechanisms based on gene classification |
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Hybridization and Low Genetic Diversity in the Endangered Alabama Red-Bellied Turtle (Pseudemys alabamensis) |
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Phylogeography of the desert scorpion Mesobuthus mongolicus illuminates a route out of Central Asia and Junggar Basin as a corridor for faunal exchange between Central and East Asia |
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Hummingbird abundance is related to food resources availability in a temperate forest of central Mexico |
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Wildlife is imperiled in peri-urban landscapes: threats to arboreal mammals |
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Spatiotemporal patterns of urban mosquitoes are modulated by socioeconomic status and environmental traits in the United States |
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A feedback loop between heterochromatin and the nucleopore complex controls germ-cell to oocyte transition during Drosophila oogenesis |
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A new tripartite landmark in posterior cingulate cortex |
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Explaining heterogeneity in medial entorhinal cortex with task-driven neural networks |
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Elementary vectors and autocatalytic sets for computational models of cellular growth |
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CompAIRR: ultra-fast comparison of adaptive immune receptor repertoires by exact and approximate sequence matching |
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Efficacy of longevity interventions in C. elegans is determined by early life activity of RNA splicing factors |
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Statistical inference in population genomics |
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Effect of plant tissues on DNA quantity and quality of barley (Hordeum vulgare) validating through PCR technique |
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Cholesterol and sphingomyelin are critical for Fcγ receptor-mediated phagocytosis of Cryptococcus neoformans by macrophages |
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Prophylactic Treatment of Undernourished Mice with Cotrimoxazole Induces a Different Profile of Dysbiosis with Functional Metabolic Alterations |
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Type 1 interferon supports B cell responses to polysaccharide antigens but is not required for MPL/TDCM adjuvant effects on innate B cells |
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Core circadian clock and light signalling genes brought into genetic linkage across the green lineage |
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Early-Stage Identification and Avoidance of Antisense Oligonucleotides Causing Species-Specific Inflammatory Responses in Human Volunteers Peripheral Blood Mononuclear Cells |
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Manual curation and phylogenetic analysis of chitinase family genes in the Asian citrus psyllid, Diaphorina citri |
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orthoSNAP: a tree splitting and pruning algorithm for retrieving single-copy orthologs from gene family trees |
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Evolution of reduced mate-harming tendency of males in Drosophila melanogaster populations selected for faster life history |
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Computational simulations reveal that Abl activity controls cohesiveness of actin networks in growth cones |
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Separable mechanisms drive local and global polarity establishment in the C. elegans intestinal epithelium |
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Transcriptional regulation of cyclophilin D by BMP/SMAD signaling and its role in osteogenic differentiation |
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The use of disinfectant in barn cleaning alters microbial composition and increases carriage of Campylobacter jejuni in broiler chickens |
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Impact of Protein Identity on Tumor-Associated Antigen Uptake into Infiltrating Immune Cells: A Comparison of Different Fluorescent Proteins as Model Antigens |
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An Immunogold Single Extracellular Vesicular RNA and Protein (AuSERP) Biochip to Predict Responses to Immunotherapy in Non-Small Cell Lung Cancer Patients |
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Btbd11 is an inhibitory interneuron specific synaptic scaffolding protein that supports excitatory synapse structure and function |
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Alpha oscillations are involved in localizing touch on hand-held tools |
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Consequences of endogenous and virally-induced hyperphosphorylated tau on behavior and cognition in a rat model of Alzheimer's disease |
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Distinct representation of cue-outcome association by D1 and D2 neurons in the olfactory striatum |
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Multi-area recordings and optogenetics in the awake, behaving marmoset |
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Pseudomonas syringae pv. tomato DC3000 Effector HopG1 is a multi-faceted protein that Triggers Necrotic Cell Death that is attenuated by the Nonhost Resistance 2B (AtNHR2B) Protein |
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DNA-free CRISPR-Cas9 gene editing of tetraploid tomatoes using protoplast regeneration |
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Maize root-associated microbes likely under adaptive selection by the host to enhance phenotypic performance |
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The influence of unmeasured confounding on the MR Steiger approach |
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Soil microbes mediate the effects of environmental variability on plant invasion |
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The expression of essential selenoproteins during zebrafish development requires SECIS binding protein 2-like |
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Immunoglobulin-producing AT2-like cells secrete IgA into the extracellular matrix in pulmonary fibrosis |
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Haspin participates in Aurora phosphorylation at centromeres and contributes to chromosome congression in male mouse meiosis |
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When Yeast Cells Change their Mind: Cell Cycle 'Start' is Reversible under Starvation |
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E-cigarette aerosol exacerbates cardiovascular oxidative stress in mice with an inactive aldehyde dehydrogenase 2 enzyme |
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Quorum sensing signal autoinducer-2 inhibits sporulation of Bacillus by interacting with RapC and functions across species |
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Plasmids as donors of Insertion Sequence elements mediating colistin resistance in Klebsiella pneumoniae |
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Conservation and divergence in cortical cellular organization between human and mouse revealed by single-cell transcriptome imaging |
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Genetic control of rhizosheath formation in pearl millet |
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Plasmotype condition nuclear pleiotropic effects on clock and fitness in barley |
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Directional selection at gene expression level contributes to the speciation of Asian rice cultivars |
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A versatile mitochondria isolation- and analysis-pipeline generates 3D nano-topographies and mechano-physical surface maps of single organelles |
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Silencing neuronal activity is required for developmental circuit remodeling |
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Vitamin A and vitamin E metabolites comodulate amyloid-β aggregation |
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Calcium fluctuations drive morphological patterning at the onset of Hydra morphogenesis |
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Oligomerization state of the functional bacterial twin arginine translocation (Tat) receptor complex |
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Ratiometric 4Pi single molecule localization with optimal resolution and color assignment |
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Development of a novel bioluminescent activity assay for peptide ligases |
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An arachnid's guide to be an ant: morphological and behavioural mimicry in ant-mimicking spiders |
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Transcriptional evaluation of the ductus arteriosus at the single-cell level uncovers a requirement for vimentin for complete closure |
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High-Speed Imaging Reveals the Bimodal Nature of Dense Core Vesicle Exocytosis and Jet Flow through the Fusion Pore |
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Transcriptional burst kinetics are linked to short term transcriptional memory |
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WY14643 Increases Herpesvirus Replication Independent of PPARα Expression and Inhibits IFNβ Production |
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Combination of successor representation-based appetitive learning and individual representation-based aversive learning is a good strategy and can be implemented in the cortico-basal ganglia circuits |
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A novel mechanism of Euonymine inhibits in-stent restenosis through enhancing contractile phenotype of VSMCs by targeting AKT1 and p38MAPK |
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#PeerReview from @eLife of ???????? Disintegration promotes proto-spacer integration by the Cas1-Cas2 complex |
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Coherent theta oscillations in the cerebellum and supplementary motor area mediate visuomotor adaptation |
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Flexible circuit mechanisms for context-dependent song sequencing |
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Microbiome restructuring: dominant coral bacterium Endozoicomonas species display differential adaptive capabilities to environmental changes |
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#PeerReview from @EMBOPress of ???????? The structure and flexibility analysis of the Arabidopsis Synaptotagmin 1 reveal the basis of its regulation at membrane contact sites |
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Synthetic periphyton as a model community to examine species dynamics in complex microbial consortia |
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Early transcriptomic response of Alnus glutinosa to Frankia alni symbiont, an upregulated nsLTP (non-specific Lipid Transfer Protein) is implicated in early and late stages of symbiosis |
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Genome-wide association study reveals complex genetic architecture of cadmium and mercury accumulation and tolerance traits in Medicago truncatula |
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Characterization of γ-Glutamyl Peptidases and γ-Glutamyl Cyclotransferases for Glutathione Degradation in Arabidopsis |
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Global transcriptome analysis reveals partial estrogen-like effects of karanjin in MCF-7 breast cancer cells |
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Substrate rigidity modulates traction forces and stoichiometry of cell matrix adhesions. |
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MFN2 Influences Amyotrophic Lateral Sclerosis Pathology |
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Acoustic Censusing and Individual Identification of Birds in the Wild |
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Autologous mitochondria transport via transzonal filopodia rejuvenates aged oocytes by UC-MSCs derived granulosa cells-oocyte aggregation |
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Intestinal GCN2 controls Drosophila systemic growth upon AA imbalance in response to Lactiplantibacillus plantarum symbiotic cues encoded by r/tRNAoperons |
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Solvation dynamics-powered structure and function of multi-molecular cellular systems exemplified by non-equilibrium cereblon-degrader-CK1α ternary complex formation |
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Examining the Ensembles of Amyloid-β Monomer Variants and their Propensities to Form Fibers Using an Energy Landscape Visualization Method |
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Electronic Mapping of a Bacterial Genome with Dual Solid-State Nanopores and Active Single-Molecule Control |
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Systems-based approach for optimization of a scalable bacterial ST mapping assembly-free algorithm |
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Genotyping of structural variation using PacBio high-fidelity sequencing |
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Extracellular Vesicles Deliver Mitochondria and HSP27 Protein to Protect the Blood-Brain Barrier |
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A simple tool extends TIMSTOF compatibility with historic data processing tools and enables ion mobility-enhanced spectral libraries |
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Plasma donation induces a protein expression profile shift in circulating human blood |
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Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokines |
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Leveraging eDNA metabarcoding to characterize nearshore fish communities in Southeast Alaska: Do habitat and tide matter? |
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A macromutation eliminates colour patterning in captive butterflies |
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Dimensionality and modularity of adaptive variation: Divergence in threespine stickleback from diverse environments |
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The colonial legacy of herbaria |
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Worldwide reef surveys highlight different adaptive responses to heat between coral taxa |
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Development and evaluation of PCR primers for environmental DNA (eDNA) metabarcoding of Amphibia |
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Polyamines mediate enterovirus attachment directly and indirectly through cellular heparan sulfate synthesis. |
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Identification and tracking of alloreactive T cell clones in Rhesus Macaques through the RM-scTCR-Seq platform. |
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Pan-cancer mapping of single T cell profiles reveals a TCF1:CXCR6-CXCL16 regulatory axis essential for effective anti-tumor immunity |
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Gigavalent display of proteins on monodisperse polyacrylamide hydrogels as a versatile modular platform for functional assays and protein engineering |
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Mem3DG: Modeling Membrane Mechanochemical Dynamics in 3D using Discrete Differential Geometry |
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Netrins and receptors control Drosophila optic lobe organization and transmedullary neuron axon targeting |
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SETD2 negatively regulates cell size through its catalytic activity and SRI domain |
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Chlamydomonas ARMC2/PF27 is an obligate cargo adapter for IFT of radial spokes |
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Neuronally Produced Betaine Acts via a Novel Ligand Gated Ion Channel to Control Behavioural States |
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Near-infrared carbon nanotube tracking reveals the nanoscale extracellular space around synapses |
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Molecular mechanism of Arp2/3 complex inhibition by Arpin |
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Mllt11 regulates the migration and neurite outgrowth of cortical projection neurons during development |
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A neural substrate for Bayesian integration in human parietal cortex |
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Onset and stepwise extensions of recombination suppression are common in mating-type chromosomes of Microbotryum anther-smut fungi |
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Double-edged role of resource competition in gene expression noise and control |
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Endogenous retroviruses mediate transcriptional rewiring in response to oncogenic signaling in colorectal cancer |
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Resistance-guided mining of bacterial genotoxins defines a family of DNA glycosylases |
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The amino acid transporter CG1139 is required for retrograde transport and fast recovery of gut enterocytes after Serratia marcescens intestinal infection |
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A comprehensive evaluation of CRISPR lineage recorders using TraceQC |
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Death and Proliferation of Lymphocytes in Immune Response and Tumor Cells Are Controlled by pH Balance |
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Modulatory potentials of zerumbone isolated from ginger (Zingiber zerumbet) on eicosanoids: evidence from LPS induced peripheral blood leukocytes. |
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Sulfotyrosine, an interaction specificity determinant for extracellular protein-protein interactions |
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Chimeric chromosome landscapes of human somatic cell cultures show dependence on stress and regulation of genomic repeats by CGGBP1. |
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Promoter sequence and architecture determine expression variability and confer robustness to genetic variants |
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Maintenance of copy number variation at the human salivary agglutinin gene (DMBT1) by balancing selection driven by host-microbe interactions |
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CTCF blocks anti-sense transcription initiation at divergent gene promoters |
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Coordinated modulation of multiple processes through phase variation of a c-di-GMP phosphodiesterase in Clostridioides difficile |
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Identification, Characterization and Synthesis of Natural Parasitic Cysteine Protease Inhibitors -- More Potent Falcitidin Analogs |
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Proteome-wide cross-linking mass spectrometry to identify specific virus capsid-host interactions between tick-borne encephalitis virus and neuroblastoma cells |
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Natural transformation protein ComFA exhibits single-stranded DNA translocase activity |
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Proteins mediating different DNA topologies block RNAP elongation with different efficiency |
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Characterization of heterologously expressed fibril filaments, a shape and motility determining cytoskeletal protein of the helical bacterium Spiroplasma |
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Effect of G4C2-Repeat Expansions on the Motion of Lysosomes Inside Neurites. |
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Lipid phase separation in vesicles enhances TRAIL-mediated cytotoxicity |
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A simple secretion assay for assessing new and existing myocilin variants |
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Illumina But With Nanopore: Sequencing Illumina libraries at high accuracy on the ONT MinION using R2C2 |
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Plasmodium DDI1 is an essential chromatin-associated protein with a role in DNA-protein crosslink repair |
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Impaired lamin localization to the nuclear envelope is responsible for nuclear damage in LMNA mutant iPSC-derived cardiomyocytes |
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mTOR inhibition via Rapamycin treatment partially reverts the deficit in energy metabolism caused by FH loss in RPE cells |
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Liberibacter solanacearum interacts with host psyllid vitellogenin with its membrane proteins |
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Silencing of an efflux pump coding gene decreases the efflux rate of pyrazinoic acid in Mycobacterium smegmatis |
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Evaluation of small non-coding RNAs as a possible epigenetic mechanism mediating the transition from biotrophy to necrotrophy in the life cycle of Phytophthora infestans |
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Blocking chondrocyte hypertrophy in conditional Evc knockout mice does not modify osteoarthritis progression |
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Saturated Proteostasis and Nuclear Injuries Defeat Homeostatic Potentials of α-Synuclein Filaments |
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The indoor mycobiome of daycare centers is affected by occupancy and climate |
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Stratification of the Gut Microbiota Composition Landscape Across the Alzheimer's Disease Continuum in a Turkish Cohort |
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Mapping neurotransmitter systems to the structural and functional organization of the human neocortex |
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Correcting the Hebbian Mistake: Toward a Fully Error-Driven Hippocampus |
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Vocal tract allometry in a mammalian vocal learner |
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Polarization and cell-fate decision facilitated by the adaptor Ste50 in Saccharomyces cerevisiae |
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Mispatterned motile cilia beating causes flow blockage in the epileptic brain |
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A Notch-dependent transcriptional mechanism controls expression of temporal patterning factors in Drosophila medulla |
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Comprehensive Structure and Functional Adaptations of the Yeast Nuclear Pore Complex |
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Cytonemes coordinate asymmetric signaling and organization in the Drosophila muscle progenitor niche |
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Double-layered two-directional somatopleural cell migration during chicken body wall development revealed with local fluorescent tissue labeling |
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R-loop mapping and characterization during Drosophila embryogenesis reveals developmental plasticity in R-loop signatures |
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Loss of Prm1 leads to defective chromatin protamination, impaired PRM2 processing, reduced sperm motility and subfertility in male mice |
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Lineage, Identity, and Fate of Distinct Progenitor Populations in the Embryonic Olfactory Epithelium |
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Elevated Hoxb5b expands vagal neural crest pool and blocks enteric neuronal development in zebrafish |
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Orb-dependent polyadenylation contributes to PLP expression and centrosome scaffold assembly |
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Intracellular pH dynamics regulates intestinal stem cell fate |
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Hidden pathway for cytokine receptor activation: Structural insights into a marine sponge-derived lectin that activates the thrombopoietin receptor via recognition of the fucose moiety |
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The early embryonic transcriptome of a Hawaiian Drosophila picture-wing fly shows evidence of altered gene expression and novel gene evolution |
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#PeerReview from @EMBOPress of ???????? Transcriptomic analysis reveals niche gene expression effects of beta-hydroxybutyrate in primary myotubes |
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#PeerReview from @eLife of ???????? Human B cell lineages engaged by germinal centers following influenza vaccination are measurably evolving |
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Extensive sequence divergence of non-coding regions between Aspergillus fumigatus, a major fungal pathogen of humans, and its relatives |
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Ribosomal protein database profiling lends clarity to ribosomal protein evolution and mass distribution |
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A cautionary tale on proper use of branch-site models to detect convergent positive selection |
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Sign inversion in selection on ploidy |
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Ormyrus labotus Walker (Hymenoptera: Ormyridae): another generalist that should not be a generalist is not a generalist |
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Activation of Npas1-neurons in the Ventral Pallidum Mediates Stress Susceptibility |
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Social experience dependent plasticity of mouse song selectivity without that of song components |
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Left angular gyrus disconnection impairs multiplication fact retrieval |
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Cell region fingerprints enable highly precise single-cell tracking and lineage reconstruction |
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Robust enhancer-gene regulation identified by single-cell transcriptomes and epigenomes |
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#PeerReview from @PeerCommunityIn of ???????? Large-scale geographic survey provides insights into the colonization history of a major aphid pest on its cultivated apple host in Europe, North America and North Africa |
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Anatomic development of the upper airway during the first five years of life: A three-dimensional imaging study |
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Notch signaling determines cell-fate specification of the two main types of vomeronasal neurons of rodents. |
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A novel role for the extraembryonic area opaca in positioning the primitive streak of the early chick embryo |
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Focal adhesion membrane is dotted with protein islands and partitioned for molecular hop diffusion |
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Cyclic uniaxial mechanical load enhances chondrogenesis through entraining the molecular circadian clock |
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Development of ultrafast camera-based imaging of single fluorescent molecules and live-cell PALM |
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Report of unexpected findings after cardiac stem cell injections in a preclinical model |
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The endoplasmic reticulum adopts two distinct tubule forms |
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Upregulated PD-1 Signaling is an Important Antagonist to Glomerular Health in Aged Kidneys |
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Changes in microbial composition, diversity, and functionality in the Amblyomma maculatum microbiome following infection with Rickettsia parkeri |
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Sensory prediction errors increase coding efficiency in mouse visual cortex through gain amplification |
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Adaptation of the gut holobiont to malnutrition during mouse pregnancy depends on the type of nutritional adversity |
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#PeerReview from @EMBOPress of ???????? Non-canonical activation of the ER stress sensor ATF6 by Legionella pneumophila effectors |
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Multi-omics analysis reveals cross-organism interactions in coral holobiont |
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Comprehensive analysis of the circadian nuclear and cytoplasmic transcriptome in mouse liver |
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ProS-GNN: Predicting effects of mutations on protein stability using graph neural networks |
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Disentangling single-cell omics representation with a power spectral density-based feature extraction |
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Bcl-xL restricts transcriptional, morphological and functional decompensation of β-cell mitochondria under chronic glucose excess |
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Aldehyde dehydrogenase 3A1 deficiency leads to mitochondrial dysfunction and impacts salivary gland stem cell self-renewal, differentiation and survival |
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The novel conserved NAD+ binding micropeptide SGHRT regulates mitochondrial function and metabolism in human cardiomyocytes |
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A basement membrane discovery pipeline uncovers network complexity, new regulators, and human disease associations |
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Activation of transient receptor potential vanilloid 4 is involved in pressure overload-induced cardiac hypertrophy |
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Epidermal Stratification Requires Retromer-Mediated Desmoglein-1 Recycling |
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The regenerative response of cardiac interstitial cells |
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Trisomy 21 increases microtubules and disrupts centriolar satellite localization |
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PU.1 expression defines distinct functional activities in the phenotypic HSC compartment in a mouse model of inflammatory stress |
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#PeerReview from @GigaScience of ???????? Detection and characterization of low and high genome coverage regions using an efficient running median and a double threshold approach. |
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Regulation of skeletal muscle metabolism and contraction performance via teneurin-latrophilin action. |
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Female choice can explain the fertilization pattern in oaks |
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Impact of Grain for Green Project on Water Resources and Ecological Water Stress in Yanhe River Basin |
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Alternative strategy to induce CRISPR-mediated genetic changes in hematopoietic cells |
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Profiling RT-LAMP tolerance of sequence variation for SARS-CoV-2 RNA detection |
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Estimated quantity of swine virus genomes based on quantitative PCR analysis in spray-dried porcine plasma samples collected from multiple manufacturing plants. |
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Effects of electroacupuncture on the expression of hypothalamic neuropeptide Y and ghrelin in pubertal rats with polycystic ovary syndrome |
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Multi-trait and multi-environment Bayesian analysis to predict the G x E interaction in flood-irrigated rice |
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In silico modeling and interactive profiling of BPH resistant R genes with elicitor molecules of rice planthoppers |
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#PeerReview from #GigaByte of ???????? Bicolor angelfish (Centropyge bicolor) provides the first chromosome-level genome of the Pomacanthidae family |
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Kinetic and data-driven modeling of pancreatic β-cell central carbon metabolism and insulin secretion |
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A suspension technique for efficient large-scale cancer organoid culturing and perturbation screens |
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Fast and parallel nanoscale 3D tracking of heterogeneous mammalian chromatin dynamics |
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Bicolor angelfish (Centropyge bicolor) provides the first chromosome-level genome of the Pomacanthidae family |
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Compatibility logic of human enhancer and promoter sequences |
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Density-dependent selection in Drosophila: evolution of egg size and hatching time |
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Stemness activity underlying whole brain regeneration in a basal chordate |
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A Prion that regulates genome diversification |
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Interleukin 7 receptor drives Early T lineage Progenitor expansion |
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Quercetin combined with Concanavalin A as a safe vaccine adjuvant that stimulates PBMCs proliferation, alleviates lipid peroxidation and boosts iNOS activity in the elderly. |
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Spatial coding in the hippocampus of flying owls |
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Cytidine deaminase protects pancreatic cancer cells from replicative stress and drives resistance to DNA-targeting drugs |
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Building tools for machine learning and artificial intelligence in cancer research: best practices and a case study with the PathML toolkit for computational pathology |
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Dynamics of lipids in the yeast lipid droplets |
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SINBAD: a flexible tool for single cell DNA methylation data |
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Assessment of Agaricus bisporus Mushroom as Protective Agent Against Ultraviolet Exposure |
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Quantification of breeding sites parameters in shaping bacterial communities in Aedes aegypti (Diptera: Culicidae). |
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Rapid decline in Western monarch butterflies leads to phenological and geographic Allee effects |
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ARP2/3- and resection-coupled genome reorganization facilitates translocations |
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Experimental microevolution of Trypanosoma cruzi reveals hybridization and clonal mechanisms driving rapid diversification of genome sequence and structure. |
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Discovery and Biosynthesis of Persiathiacins: Unusual Polyglycosylated Thiopeptides Active against Multi-drug resistant Tuberculosis |
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SARS-CoV-2 Infection Impacts Carbon Metabolism and Depends on Glutamine for Replication in Syrian Hamster Astrocytes |
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Protection from SARS-CoV-2 Delta one year after mRNA-1273 vaccination in nonhuman primates is coincident with an anamnestic antibody response in the lower airway |
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A transcriptomic axis predicts state modulation of cortical interneurons |
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Tsetse RNA Virome: Novel Iflavirus Genomes in Glossina morsitans and Other Tsetse Species |
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The humanized nanobody RBD-1-2G tolerates the spike N501Y mutation to neutralize SARS-CoV-2 |
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NLR immune receptor-nanobody fusions confer plant disease resistance |
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Characterization of raloxifene as potential pharmacological agent against SARS-CoV-2 and its variants |
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The proteasome regulator PSME4 drives immune evasion and abrogates anti-tumor immunity in NSCLC |
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A focal adhesion kinase-YAP signaling axis drives drug tolerant persister cells and residual disease in lung cancer |
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Single-cell transcriptional analysis of the immune tumour microenvironment during myeloma disease evolution |
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Computational correction of cell-specific gene-independent effects in CRISPR-Cas9 essentiality screens: REStricted CUbic SplinEs with Mixed Models (RESCUE-MM) |
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ICA treatment diabets induced bone loss via primary cilia/Gli2/Osteocalcin signaling pathway |
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Inactivation of SARS Coronavirus 2 and COVID-19 patient samples for contemporary immunology and metabolomics studies |
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Multiple paths lead to salt tolerance - pre-adaptation vs dynamic responses from two closely related extremophytes |
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NanoSplicer: Accurate identification of splice junctions using Oxford Nanopore sequencing |
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Benchmarking AlphaFold for protein complex modeling reveals accuracy determinants |
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Oral administration of bacterial Beta cell expansion factor A (BefA) alleviates diabetes in mice with Type 1 and Type 2 diabetes |
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Excessive fetal growth affects HSC quiescence maintenance through epigenetic programming of EGR1 transcriptional network |
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Habitat determines convergent evolution of cephalic horns in vipers |
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The role of mitochondrial energetics in the origin and diversification of eukaryotes |
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Alternative Cdc20 translational isoforms bypass the spindle assembly checkpoint to control mitotic arrest duration |
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MRGM: a mouse reference gut microbiome reveals a large functional discrepancy for gut bacteria of the same genus between mice and humans |
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Previously uncharacterized rectangular bacteria in the dolphin mouth |
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Transcriptional regulation of photoprotection in dark-to-light transition - more than just a matter of excess light energy |
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ZELDA: a 3D Image Segmentation and Parent-Child relation plugin for microscopy image analysis in napari |
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Genomic insights into variation in thermotolerance between hybridizing swordtail fishes |
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Molecular basis of ocean acidification sensitivity and adaptation in Mytilus galloprovincialis |
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Flexible neural coding in sensory, parietal, and frontal cortices during goal-directed virtual navigation |
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Optimal confidence for unaware visuomotor deviations |
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Two structurally different oomycete MAMPs induce distinctive plant immune responses. |
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RAGE antagonist peptide mitigates AGE-mediated endothelial hyperpermeability and accumulation of glycoxidation products in human ascending aortas and in a murine model of aortic aneurysm |
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Sexual identity of enterocytes regulates rapamycin-mediated intestinal homeostasis and lifespan extension |
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Wiring multiple microenvironment proteomes uncovers the biology in head and neck cancer |
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Shared hotspot mutations in spontaneously arising cancers position dog as an unparalleled comparative model for precision therapeutics |
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A Developmentally Prometastatic Niche to Hepatoblastoma in Neonatal Liver mediated by the Cxcl1/Cxcr2 Axis |
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Classical Mathematical Models for Prediction of Response to Chemotherapy and Immunotherapy |
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The mechanosensitive TRPV2 calcium channel controls melanoma invasiveness and metastatic potential. |
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A noval lightsheet scattering microscopy for long-term visualization of cell-ECM interaction |
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Loss-of-function, gain-of-function and dominant-negative mutations have profoundly different effects on protein structure: implications for variant effect prediction |
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End-to-end learning of multiple sequence alignments with differentiable Smith-Waterman |
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Retinal self-organization: a model of RGC and SAC mosaic formation |
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DeePVP: Identification and classification of phage virion protein using deep learning |
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Accurate estimation of intrinsic biases for improved analysis of chromatin accessibility sequencing data using SELMA |
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Versatile Encapsulation and Synthesis of Potent Therapeutic Liposomes by Thermal Equilibration |
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Green notes: The rhythms of cyanobacteria exoelectrogenesis as de-composed by the Hilbert-Huang transform |
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Inference of cell state transitions and cell fate plasticity from single-cell with MARGARET |
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Drift on holey landscapes as a dominant evolutionary process |
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Structure and dynamics of Odinarchaeota tubulin and the implications for eukaryotic micr |