Barzooka - Fighting against bar graphs for continuous data!

Barzooka is a deep convolutional neural network that screens publication PDFs and checks for bar graphs of continuous data and other common graphing issues. Many different data distributions can lead to the same bar graph and the actual data may suggest different conclusions from the summary statistics alone. Barzooka also detects more informative alternatives to bar graphs, like dot plots, box plots and histograms. This website shows the detection of bar graphs for continuous data in bioRxiv preprints. A screening pipeline retrieves new preprints on a daily basis and screens them for bar graphs for continuous data. Preprints with bar graph detection are highlighted (column 'parse status') as well as the detected pages (click on 'View results'). Future interventions are planned to inform the authors of preprints about better alternatives for bar graphs.

View Results Title Date Posted Paper Link Parse Status Authors notified?
Maternal thyroid hormone increases neural cell diversity during zebrafish spinal cord neurodevelopment. 2022-02-27 Not yet
Multiomic profiling defines cell fate plasticity of in vitro-derived islets 2022-02-27 Not yet
NEDD8 activity is important for direct antigen MHC class I antigen presentation 2022-02-27 Not yet
Transition between conformational states of the TREK-1 K2P channel promoted by interaction with PIP2 2022-02-27 Not yet
Obesity disrupts innate-adaptive immune network patterning in adipose tissue 2022-02-27 Not yet
Oropouche orthobunyavirus infection is mediated by the cellular host factor Lrp1 2022-02-27 Not yet
Transcription factor paralogs orchestrate alternative gene regulatory networks by context-dependent cooperation with multiple cofactors 2022-02-27 Not yet
Tango for Two: Modeling Synchronization and Social Interaction in Turn-Taking 2022-02-27 Not yet
Protection of Hamsters Challenged with SARS-CoV-2 after Two Doses of MVC-COV1901 Vaccine Followed by a Single Intranasal Booster with Nanoemulsion Adjuvanted S-2P Vaccine 2022-02-26 Not yet
The GENOMES UNCOUPLED1 protein has an ancient, highly conserved role in chloroplast gene expression but not in retrograde signalling 2022-02-26 Not yet
PSMA-bearing extracellular vesicles secreted from prostate cancer convert the microenvironment to a tumor-supporting, pro-angiogenic state. 2022-02-26 Not yet
Transcriptomic landscapes of SARS-CoV-2-infected and bystander lung cells reveal a selective upregulation of NF-κB-dependent coding and non-coding proviral transcripts 2022-02-26 Not yet
Early events in reovirus infection influence induction of innate immune response 2022-02-26 Not yet
Conservation and evolution of the sporulation gene set in diverse members of the Firmicutes 2022-02-26 Not yet
Cryo-EM structure of the Rhodobaca bogoriensis RC-LH1-PufX dimeric complex at 2.9 angstrom 2022-02-26 Not yet
A general theory of specific binding: insights from a genetic, mechano-chemical protein model 2022-02-26 Not yet
Natural Variation Meets Synthetic Biology: Promiscuous Trichome Expressed Acyltransferases from Nicotiana acuminata 2022-02-26 Not yet
Long-Term Culture of Patient-Derived Cardiac Organoids Recapitulated Duchenne Muscular Dystrophy Cardiomyopathy and Disease Progression 2022-02-26 Not yet
Human cytomegalovirus vMIA inhibits MAVS oligomerization at peroxisomes in an MFF-dependent manner 2022-02-26 Not yet
Blood cells communicate remotely via an NMDA receptor-mediated glutamatergic chain-reaction 2022-02-26 Not yet
A novel missense mutation in the proprotein convertase gene furinb causes hepatic cystogenesis during liver development in zebrafish 2022-02-26 Not yet
EagleImp-Web: A Fast and Secure Genotype Phasing and Imputation Web Service using Field-Programmable Gate Arrays 2022-02-26 Not yet
Cortical compensation for afferent loss in older adults: Associations with GABA and speech recognition in noise 2022-02-25 Not yet
Herpes Simplex Virus Reactivation Induced Ex Vivo Involves a DLK-Dependent but Histone Demethylase-Independent Wave of Lytic Gene Expression 2022-02-25 Not yet
The Neisseria meningitidis iron acquisition protein HpuA moonlights as an adhesin and inhibits host cell migration 2022-02-25 Not yet
The lipid raft-associated protein stomatin is required for accumulation of dectin-1 in the phagosomal membrane and for full activity of macrophages against Aspergillus fumigatus 2022-02-25 Not yet
Generation of PRKN and PINK1-KO and double KO cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 editing 2022-02-25 Not yet
Deficiency of the RNA-binding protein Cth2 extends yeast replicative lifespan by alleviating its repressive effects on mitochondrial function 2022-02-25 Not yet
Human HspB1, HspB3, HspB5 and HspB8: Shaping these Disease Factors during Vertebrate Evolution 2022-02-25 Not yet
Bimodal breeding phenology in the parsley frog Pelodytes punctatus as a bet-hedging strategy in an unpredictable environment despite strong priority effects 2022-02-25 Not yet
The circ_0002538/miR-138-5p/PLLP axis regulates Schwann cell migration and myelination in diabetic peripheral neuropathy 2022-02-25 Not yet
ABIOTIC STRESS GENE 1 mediates aroma volatiles accumulation by activating MdLOX1a in apple 2022-02-25 Not yet
An open, analysis-ready, and quality controlled resource for pediatric brain white-matter research 2022-02-25 Not yet
A Geometric View of Signal Sensitivity Metrics in multi-echo fMRI 2022-02-25 Not yet
Dissecting the effects of adaptive encoding and predictive inference on a single perceptual estimation 2022-02-25 Not yet
Direct and delayed synergistic effects of marine heatwaves, metals and food limitation on tropical reef-associated fish larvae 2022-02-25 Not yet
Structural and functional alterations of neuromuscular synapses in a mouse model of ACTA1 congenital myopathy 2022-02-25 Not yet
Olfactory responses of Drosophila are encoded in the organization of projection neurons 2022-02-25 Not yet
Active exploration of a novel environment drives the activation of the hippocampus-amygdala complex of domestic chicks. 2022-02-25 Not yet
Performance reserves in brain-imaging-based phenotype prediction 2022-02-25 Not yet
Uncertainty Quantification in Variable Selection for Genetic Fine-Mapping using Bayesian Neural Networks 2022-02-25 Not yet
Prediction of sex-determination mechanisms in avian primordial germ cells using RNA-seq analysis 2022-02-25 Not yet
Kinetochore- and chromosome-driven transition of microtubules into bundles promotes spindle assembly 2022-02-25 Not yet
An apical membrane complex controls rhoptry exocytosis and invasion in Toxoplasma 2022-02-25 Not yet
Zebrafish Neuromesodermal Progenitors Undergo a Critical State Transition in vivo 2022-02-25 Not yet
An Agrobacterium strain auxotrophic for methionine is useful for switchgrass transformation 2022-02-25 Not yet
High Cellular Uptake Gene Delivery Platform with Chitosan and L-arginine Complex for Cancer Treatment 2022-02-25 Not yet
Negative Impact of Daily Screen Use on Inhibitory Control Network in Preadolescence: A Two Year Follow-Up Study 2022-02-25 Not yet
In vitro evolution of Listeria monocytogenes reveals selective pressure for loss of SigB and AgrA function at different incubation temperatures. 2022-02-25 Not yet
Increased vulnerability of Purkinje cells in the posterior cerebellum of SCA1 mice is associated with molecular and cellular alterations related to disease pathology 2022-02-25 Not yet
Myelin lipids as nervous system energy reserves 2022-02-25 Not yet
Population Dynamics and Resource Availability Drive Seasonal Shifts in the Consumptive and Competitive Impacts of Introduced House Mice (Mus musculus) on an Island Ecosystem 2022-02-24 Not yet
Three-dimensional cilia structures from animals' closest unicellular relatives, the Choanoflagellates 2022-02-24 Not yet
Dynamic genetic adaptation of Bacteroides thetaiotaomicron murine gut colonization 2022-02-24 Not yet
The inhibitory effect of EGCG-AgNP-lysozyme bioconjugates on biofilm formation 2022-02-24 Not yet
Chlamydomonas mutant hpm91 lacking PGR5 is a scalable and valuable strain for algal hydrogen (H2) production 2022-02-24 Not yet
Identification of cytoplasmic chaperone networks relevant for respiratory syncytial virus replication 2022-02-24 Not yet
Screening and Identification of Azo Dye Decolourizers from Mangrove Rhizospheric soil 2022-02-24 Not yet
Prevalence and mechanisms of evolutionary contingency in human influenza H3N2 neuraminidase 2022-02-24 Not yet
LUBAC is required for RIG-I sensing of RNA viruses 2022-02-24 Not yet
Metabolic Engineering of Oleaginous Yeast Rhodotorula toruloides for Overproduction of Triacetic Acid Lactone 2022-02-24 Not yet
Induction of tumor-initiating cells and glioma-initiating cells from fetal neural stem cells through p53 genome editing 2022-02-24 Not yet
AIMP1-derived peptide secreted from hair follicle stem cells activates dermal papilla cells to promote hair growth 2022-02-24 Not yet
Functional stemness-related genes revealed by single-cell profiling of naïve and stimulated human CD34+ cells from CB and mPB 2022-02-24 Not yet
Early identification of cooperative fragments for protein-protein interaction stabilization 2022-02-24 Not yet
A Neural Model of Task Compositionality with Natural Language Instructions 2022-02-24 Not yet
mRNA Treatment Rescues Niemann-Pick Disease Type C1 in Patient Fibroblasts 2022-02-24 Not yet
Distinct glycerophospholipids potentiate Gsα-activated adenylyl cyclase activity 2022-02-24 Not yet
Convergence of monosynaptic inputs from neurons in the brainstem and forebrain on parabrachial neurons that project to the paraventricular nucleus of the thalamus 2022-02-24 Not yet
Using dilution grazing assays to measure size fractionated phytoplankton mortality rates across the freshwater-to-marine continuum 2022-02-24 Not yet
222-nm far UVC exposure results in DNA damage and transcriptional changes to mammalian cells. 2022-02-24 Not yet
Single-cell analysis of skeletal muscle macrophages reveals age- associated functional subpopulations 2022-02-24 Not yet
Melanin Nanoparticles as an Alternative to Natural Melanin in Retinal Pigment Epithelium Cells and Their Therapeutic Effects against Age-Related Macular Degeneration 2022-02-24 Not yet
The extracellular sialidase NEU3 induces neutrophil priming 2022-02-24 Not yet
Antisense modulation of IL7R splicing to control sIL7R expression in human CD4 T cells 2022-02-24 Not yet
Odorant receptor orthologues in conifer-feeding beetles display conserved responses to ecologically relevant odors 2022-02-24 Not yet
Regional and cell type-specific afferent and efferent projections of the mouse claustrum 2022-02-24 Not yet
Detection of functional activity in brain white matter using fiber architecture informed synchrony mapping 2022-02-24 Not yet
Rank Selection Genetic Algorithm optimises robust parameter estimation for systems biology models 2022-02-23 Not yet
Frequency dependent growth of bacteria in living materials 2022-02-24 Not yet
Confirming Multiplex Q-PCR Use in COVID-19 with Next Generation Sequencing: Strategies for Epidemiological Advantage 2022-02-23 Not yet
Systemic RNA interference-defective (SID) genes modulate dopaminergic neurodegeneration in C. elegans 2022-02-24 Not yet
Adaptations for bipedal walking: Musculoskeletal structure and three-dimensional joint mechanics of humans and bipedal chimpanzees (Pan troglodytes) 2022-02-23 Not yet
Coursing hyenas and stalking lions: the potential for inter- and intraspecific interactions 2022-02-24 Not yet
Expression of Unfolded Protein Response Genes in Post-transplantation Liver Biopsies 2022-02-23 Not yet
Transertion is used for localized expression and assembly of Vibrio parahaemolyticus T3SS2 2022-02-23 Not yet
Potent Neutralizing Activity of Polyclonal Equine Antibodies against Omicron SARS-CoV-2 2022-02-23 Not yet
Resistance of Dickeya solani strain IPO 2222 to lytic bacteriophage vB_Dsol_D5 ({Phi}D5) results in fitness tradeoffs for the bacterium during infection 2022-02-23 Not yet
Characterization of various remdesivir-resistant mutations of SARS-CoV-2 by mathematical modeling and molecular dynamics simulation. 2022-02-24 Not yet
SARS-CoV-2 Variant Delta Potently Suppresses Innate Immune Response and Evades Interferon-Activated Antiviral Responses 2022-02-23 Not yet
Efficacy and sex differences in the effects on rat brain microglia of the colony-stimulating factor 1 receptor inhibitor-PLX5622 2022-02-23 Not yet
Functional involvement of multiple genes as members of the supergene unit in the female-limited Batesian mimicry of Papilio polytes 2022-02-23 Not yet
Live-Cell Imaging in Human Colonic Monolayers Reveals Erk Waves Limit the Stem Cell Compartment to Maintain Epithelial Homeostasis 2022-02-23 Not yet
PERK Signaling Promotes Mitochondrial Elongation By Remodeling Membrane Phosphatidic Acid 2022-02-23 Not yet
Population structure and genetic connectivity of the scalloped hammerhead shark (Sphyrna lewini) across nursery grounds from the Eastern Tropical Pacific: implications for management and conservation 2022-02-22 Not yet
Loss of E-cadherin Induces IGF1R Activation Revealing a Targetable Pathway in Invasive Lobular Breast Carcinoma 2022-02-22 Not yet
Characterization of Arabian Peninsula whole exomes: exploring high inbreeding features 2022-02-22 Not yet
Lysine acetylation regulates antibiotic resistance in Escherichia coli 2022-02-22 Not yet
Edible formulations of chicken egg derived IgY antibodies neutralize SarsCoV2 Omicron RBD binding to human ACE2 2022-02-22 Not yet
Prepronociceptin-expressing neurons in the extended amygdala signal darting away from an aversive odor 2022-02-22 Not yet
A Novel Chronic in vivo Oral Cadmium Exposure-Washout Mouse Model for Studying Cadmium Toxicity and Complex Diabetogenic Effects 2022-02-22 Not yet
Multimodal Thrombectomy Device for Treatment of Acute Deep Venous Thrombosis 2022-02-22 Not yet
SexFindR: A computational workflow to identify young and old sex chromosomes 2022-02-22 Not yet
Liver lipophagy ameliorates nonalcoholic steatohepatitis through lysosomal lipid exocytosis 2022-02-22 Not yet
Stability And Shelf-Life Of Plasma Bubbling Treated Cow Milk 2022-02-22 Not yet
Estrogen suppresses DMRT1 expression during ovarian development in the chicken 2022-02-22 Not yet
Impaired Lef1 activation accelerates iPSC-derived keratinocytes differentiation in Progeria 2022-02-22 Not yet
Blockage of Lamin-A/C loss diminishes the pro-inflammatory macrophage response 2022-02-22 Not yet
Identification of a SARS-CoV-2 host metalloproteinase-dependent entry pathway differentially used by SARS-CoV-2 and variants of concern Alpha, Delta, and Omicron 2022-02-22 Not yet
Alterations in SARS-CoV-2 Omicron and Delta peptides presentation by HLA molecules 2022-02-22 Not yet
SARS-CoV-2 Viroporins Activate The NLRP3-Inflammasome Via The Mitochondrial Permeability Transition Pore 2022-02-22 Not yet
Hormone levels increase in response to video playback in the Siamese fighting fish 2022-02-22 Not yet
Inositol depletion regulates phospholipid metabolism and activates stress signaling in HEK293T cells 2022-02-22 Not yet
Do we parse the background into separate streams in the cocktail party? 2022-02-22 Not yet
A novel dimeric FAP-targeting small molecule-radio conjugate with high and prolonged tumour uptake 2022-02-22 Not yet
Seasonal dynamics and polyphenism of butterfly communities in the coastal plains of central Western Ghats, India 2022-02-22 Not yet
An Improved Linear Mixed Model for Multivariate Genome-Wide Association Studies 2022-02-22 Not yet
The effects of caloric restriction on adipose tissue and metabolic health are sex- and age-dependent 2022-02-22 Not yet
Reactive astrocytes transduce blood-brain barrier dysfunction through a TNFα-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin 2022-02-22 Not yet
Quantitative Proteomic Profiling of Murine Embryonic Heart Development Reveals a Role for the Mevalonate Pathway in Cardiomyocyte Proliferation 2022-02-22 Not yet
Molecular Signatures and Cellular Diversity During Mouse Habenula Development 2022-02-22 Not yet
Brassinosteroids modulate autophagy through phosphorylation of RAPTOR1B by the GSK3-like kinase BIN2 in Arabidopsis 2022-02-22 Not yet
A Facile Method to Produce N-Terminally Truncated α-Synuclein 2022-02-22 Not yet
Antisense non-coding transcription represses the PHO5 model gene via remodelling of promoter chromatin structure 2022-02-21 Not yet
Comparison of two sampling, quenching and extraction methods for quantitative yeasts metabolomics 2022-02-21 Not yet
A phospholipase assay screen identifies synergistic inhibitors of the P. aeruginosa toxin ExoU 2022-02-21 Not yet
Staphylococcus aureus overcomes anaerobe-derived short-chain fatty acid stress via FadX and the CodY regulon 2022-02-21 Not yet
Soluble extracts from amnion and chorion membranes improve hMSC osteogenic response in a mineralized collagen scaffold 2022-02-21 Not yet
Allosteric interactions prime androgen receptor dimerization and activation 2022-02-21 Not yet
PBRM1 is a vulnerability in ARID1A deficient multicellular tumor spheroids 2022-02-21 Not yet
From bacteria to plants: a repurposing strategy in the pursuit for novel herbicides 2022-02-21 Not yet
Phosphatidic acid inhibits inositol synthesis by inducing nuclear translocation of IP6K1 and repression of myo-inositol-3-P synthase 2022-02-21 Not yet
Microbial electrochemical systems for enhanced degradation of glyphosate: Electrochemical performance, degradation efficiency, and analysis of the anodic microbial community 2022-02-21 Not yet
Spontaneous behavioural recovery following stroke relates to the integrity of sensory and association cortices 2022-02-21 Not yet
Combined single-cell RNA-seq profiling and enhancer editing reveals critical spatiotemporal controls over thalamic nuclei formation in the murine embryo 2022-02-20 Not yet
Urocortin-3 neurons in the perifornical area mediate the impact of chronic stress on female infant-directed behavior 2022-02-20 Not yet
Synaptic Location Is a Determinant of the Detrimental Effects of α-Synuclein Pathology to Glutamatergic Transmission in the Basolateral Amygdala 2022-02-20 Not yet
Keratinocyte-Associated Protein 3 is a novel gene for adiposity with differential effects in males and females 2022-02-20 Not yet
Use of sugarcane mosaic virus for virus-induced gene silencing in maize 2022-02-20 Not yet
The effects of brief heat during early booting on reproductive, developmental and physiological performance in common wheat (Triticum aestivum L.) 2022-02-20 Not yet
Resistance to EGFR inhibitors in lung cancer occurs through horizontal transfer and is associated with increased caveolins expression 2022-02-20 Not yet
Zn-dependent structural transition of SOD1 modulates its ability to undergo liquid-liquid phase separation. 2022-02-20 Not yet
Molecular insights into the recognition of acetylated histone modifications by the BRPF2 bromodomain 2022-02-20 Not yet
Mitotic bookmarking by CTCF controls selected genes during the fast post-mitotic genome reactivation of ES cells 2022-02-20 Not yet
Improved Heat Tolerance in Heat-acclimated Mice: the Probable Role of the PD-L1 Pathway 2022-02-20 Not yet
Measuring brain beats: cardiac-aligned fast fMRI signals 2022-02-20 Not yet
Unsupervised physiological noise correction of fMRI data using phase and magnitude information (PREPAIR) 2022-02-20 Not yet
Exploring the link between Parkinson's disease and Diabetes Mellitus in Drosophila 2022-02-20 Not yet
Inducing synthetic lethality for selective targeting of acute myeloid leukemia cells harboring STAG2 mutations 2022-02-20 Not yet
Differential binding of salicylic acid, phenolic acid derivatives and co- factors determines the roles of Arabidopsis NPR1 to NPR4 in plant immunity 2022-02-19 Not yet
Resolving drug selection and migration in an inbred South American Plasmodium falciparum population with identity-by-descent analysis 2022-02-19 Not yet
Effective infection with dengue virus in experimental neonate and adult mice through intranasal route 2022-02-19 Not yet
An NKX-COUP-TFII genomic code for mucosal vascular addressins and organ morphogenesis 2022-02-19 Not yet
Tyrosine kinase inhibitors trigger lysosomal damage-associated cell lysis to activate the NLRP3 inflammasome 2022-02-19 Not yet
Single-cell immune profiling reveals novel thymus-seeding populations, T cell commitment, and multi-lineage development in the human thymus 2022-02-19 Not yet
Strigolactones are chemoattractants for host tropism in Orobanchaceae parasitic plants 2022-02-19 Not yet
Choosing variant interpretation tools for clinical applications: context matters 2022-02-19 Not yet
Reconstruction of hundreds of reference ancestral genomes across the eukaryotic kingdom 2022-02-19 Not yet
Modulation of sleep by trafficking of lipids through the Drosophila blood brain barrier 2022-02-19 Not yet
Enhanced photosynthetic efficiency for increased carbon assimilation and woody biomass production in hybrid poplar INRA 717-1B4 2022-02-19 Not yet
Assessing Protein Homology Models with Docking Reproducibility 2022-02-19 Not yet
Generating an in vitro gut model with physiologically relevant biophysical mucus properties 2022-02-19 Not yet
Multi-ancestry genome-wide analysis identifies common genetic variants for self-reported sleep duration and shared genetic effects 2022-02-19 Not yet
Notch signaling in tumor vasculature programs cancer-associated fibroblasts to suppress anti-tumor immunity 2022-02-19 Not yet
Activation and inhibition of the C-terminal kinase domain of p90 ribosomal S6 kinases 2022-02-19 Not yet
Silencing KCC2 in mouse dorsal hippocampus compromises spatial and contextual memory 2022-02-19 Not yet
D2 dopamine receptor expression, sensitivity to rewards, and reinforcement learning in a complex value-based decision-making task 2022-02-19 Not yet
Multi-omics approach reveals dysregulation of protein phosphorylation correlated with lipid metabolism in mouse fatty liver 2022-02-19 Not yet
Secondary sexual dimorphism traits under abiotic stress in dioecious species: The case of Amaranthus palmeri 2022-02-19 Not yet
Periductal bile acid exposure causes cholangiocyte injury and fibrosis 2022-02-19 Not yet
Hypoxia modulates cellular endocytic pathways and organelles with enhanced cell migration and 3D cell invasion 2022-02-19 Not yet
MoveApps - a serverless no-code analysis platform for animal tracking data 2022-02-19 Not yet
AAV2/9-mediated gene transfer into murine lacrimal gland leads to a long-term targeted tear film modification 2022-02-19 Not yet
TAMC: A deep-learning approach to predict motif-centric transcriptional factor binding activity based on ATAC-seq profile 2022-02-19 Not yet
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds 2022-02-19 Not yet
Mechanisms of frustrated phagocytic spreading of human neutrophils on antibody-coated surfaces 2022-02-19 Not yet
MicroRNA-155 regulates osteogenesis and bone mass phenotype via targeting S1PR1 gene 2022-02-19 Not yet
A Ferroptosis-mediated regulation of the biogenesis of the oxidative phosphorylation system 2022-02-19 Not yet
Prolonged β-Adrenergic Stimulation Disperses Ryanodine Receptor Clusters in Cardiomyocytes: Implications for Heart Failure 2022-02-19 Not yet
Dilated cardiomyopathy mutation E525K in human beta-cardiac myosin stabilizes the interacting heads motif and super-relaxed state of myosin 2022-02-19 Not yet
Specific attenuation of purinergic signaling during bortezomib-induced peripheral neuropathy 2022-02-18 Not yet
Synthetic lethality between toxic amino acids, retrograde target genes and chaperones in Saccharomyces cerevisiae 2022-02-18 Not yet
Inhibition of the tuft cell/ILC2 axis reduces gastric tumor development in mice 2022-02-18 Not yet
ABPP-HT* - Deep meets fast for activity-based profiling of deubiquitylating enzymes using advanced DIA and DDA mass spectrometry methods 2022-02-18 Not yet
Development of a Novel Peptide Aptamer that Interacts with the eIF4E Capped-mRNA Binding Site using Peptide Epitope Linker Evolution (PELE). 2022-02-18 Not yet
DJ-1 glyoxalase activity makes a modest contribution to cellular defense against methylglyoxal damage in neurons 2022-02-18 Not yet
The Chlamydia protein CpoS modulates the inclusion microenvironment and restricts the interferon response by acting on Rab35 2022-02-18 Not yet
The effect of cytoskeleton inhibitors on coccolith morphology in Coccolithus braarudii and Scyphosphaera apsteinii 2022-02-18 Not yet
Aquatic long-term persistence of Francisella tularensis ssp. holarctica is driven by water temperature and transition to a viable but non-culturable state 2022-02-18 Not yet
Mosaic receptor-binding domain nanoparticles induce protective immunity against SARS-CoV-2 challenges 2022-02-18 Not yet
Nuclear Receptor 5A2 Regulation of Agrp underlies Olanzapine-induced Hyperphagia 2022-02-18 Not yet
Design of a Versatile Microfluidic Device for Imaging Precision-Cut-Tissue Slices 2022-02-18 Not yet
IKK2/NFkB signaling controls lung resident CD8 T cell memory during influenza infection 2022-02-18 Not yet
Leishmania amazonensis infection induces PD-L1 expression on dendritic cells in an mTor-dependent manner and impairs Th1 responses in vitro and in vivo 2022-02-18 Not yet
A two-gene strategy increases the iron and zinc concentration of wheat flour and improves mineral bioaccesibility for human nutrition. 2022-02-18 Not yet
Spatial patterns of biomass change across Finland in 2009 - 2015 2022-02-18 Not yet
Low Density Lipoprotein Receptor-Related Protein 1 (LRP1) is a host factor for RNA viruses including SARS-CoV-2 2022-02-18 Not yet
Abscisic Acid modulates neighbor proximity-induced leaf hyponasty in Arabidopsis 2022-02-18 Not yet
E-cadherin is sorted by Rab7 and Snx16 for polarised secretion via Myosin V 2022-02-18 Not yet
Atypical MAPK regulates translocation of GATA transcription factor in response to chemoattractant stimulation 2022-02-18 Not yet
Mechanism of Voltage Gating in the Voltage-Sensing Phosphatase Ci-VSP 2022-02-18 Not yet
Molecular mechanisms of spontaneous curvature and softening in complex lipid bilayer mixtures 2022-02-18 Not yet
Lens aquaporin-5 inserts into bovine fiber cell plasma membranes through mitochondria-associated lysosome secretion 2022-02-18 Not yet
Contribution of the Wolffian duct mesenchyme to the formation of the female reproductive tract 2022-02-18 Not yet
Spatiotemporal analysis of axonal autophagosome-lysosome dynamics reveals limited fusion events trigger two-step maturation 2022-02-18 Not yet
MafB, WDR77, and ss-catenin interact with each other and have similar genome association profiles 2022-02-17 Not yet
A new insight into MYC action: control of RNA polymerase II methylation and transcription termination 2022-02-17 Not yet
The stationary phase-specific sRNA fimR2 is a multifunctional regulator of bacterial motility, biofilm formation and virulence 2022-02-17 Not yet
A novel fluorescent multi-domain protein construct reveals the individual steps of the unfoldase action of Hsp70 2022-02-17 Not yet
CipA mediates complement resistance of Acinetobacter baumannii by formation of a Factor I-dependent quadripartite assemblage 2022-02-17 Not yet
Distinct physiological responses of Coccolithus braarudii life cycle phases to light intensity and nutrient availability 2022-02-17 Not yet
Transmission risk assessment of Aedes-borne arboviral diseases in Accra, Ghana 2022-02-17 Not yet
A natural broad-spectrum inhibitor of enveloped virus entry, effective against SARS-CoV-2 and Influenza A Virus in preclinical animal models. 2022-02-17 Not yet
Biomechanical dependence of SARS-CoV-2 infections 2022-02-17 Not yet
Normalization of aperiodic ECoG components indicates fine motor recovery after sensory cortical stroke in mice 2022-02-17 Not yet
Perceptual consequences of interocular imbalances in the duration of temporal integration 2022-02-17 Not yet
Sequential increase of PHGDH expression with Alzheimer's pathology and symptoms 2022-02-17 Not yet
Inducing a mental context for associative memory formation with real-time fMRI neurofeedback 2022-02-17 Not yet
Task-specific effects of biological sex and sex hormones on object recognition memories in a 6-hydroxydopamine-lesion model of Parkinson's disease in adult male and female rats 2022-02-17 Not yet
Melanosomes degrade lipofuscin and precursors that are derived from photoreceptor membrane turnover in the retinal pigment epithelium--an explanation for the origin of the melanolipofuscin granule 2022-02-17 Not yet
A network of cytosolic (co)chaperones promotes the biogenesis of mitochondrial signal-anchored outer membrane proteins 2022-02-17 Not yet
Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning 2022-02-17 Not yet
Prediction of range expansion and estimation of dispersal routes of water deer (Hydropotes inermis) in the transboundary region between China, the Russian Far East and the Korean Peninsula 2022-02-16 Not yet
High-throughput detection and quantification of phosphatidylcholines and sphingomyelins from single cells by chip-based nanoelectrospray ionisation 2022-02-16 Not yet
Hypoxic response is driven by the BAF form of SWI/SNF 2022-02-16 Not yet
Dissociable roles of theta and alpha in sub-second and supra-second time reproduction:An investigation of their links to depression and anxiety 2022-02-16 Not yet
Substrate topology and cognate immunity modulate antibacterial toxicity of Tae cell wall hydrolases 2022-02-16 Not yet
A small molecule probe elucidates the role of mitochondrial translocase TIMM44 in PINK1/Parkin regulated mitophagy 2022-02-16 Not yet
Structural basis for interaction between CLAMP and MSL2 proteins involved in the specific recruitment of the dosage compensation complex in Drosophila 2022-02-16 Not yet
The Conserved CNOT1 Interaction Motif of Tristetraprolin Regulates ARE-mRNA Decay Independently of the p38 MAPK-MK2 Kinase Pathway 2022-02-16 Not yet
Neurovascular Uncoupling: Multimodal Imaging Delineates the Acute Effects of MDMA 2022-02-16 Not yet
Tideglusib mitigates dystrophic pathology in skeletal muscle and restores diastolic function in young D2 mdx mice 2022-02-16 Not yet
Chemophototherapy Overcomes Doxorubicin Resistance in Human Ovarian Cancer Cells 2022-02-16 Not yet
Quantitatively defining species boundaries with moreefficiency and more biological realism 2022-02-16 Not yet
Editing the CsDMR6 Gene in Citrus Results in Resistance to the Bacterial Disease Citrus Canker 2022-02-16 Not yet
Comprehensive analysis of Arabidopsis thaliana DNA polymerase epsilon catalytic subunit A and B mutants - an insight into differentially expressed genes and protein-protein interactions 2022-02-16 Not yet
Single-cell characterization of neovascularization using hiPSC-derived endothelial cells in a 3D microenvironment 2022-02-16 Not yet
Directed differentiation of EA/TEF patient-derived induced pluripotent stem cells into esophageal epithelial organoids reveal SOX2 dysregulation at the anterior foregut stage 2022-02-16 Not yet
Transcriptomic mapping of the metzincin landscape in human trophoblasts 2022-02-16 Not yet
Recombinant production of growth factors for application in cell culture 2022-02-16 Not yet
Modeling of protein conformational changes with Rosetta guided by limited experimental data 2022-02-16 Not yet
Probing local chromatin dynamics by tracking telomeres 2022-02-16 Not yet
Biochemical analysis challenging Western blot analysis as validation step for antibodies intended for ELISA and immunohistochemistry 2022-02-15 Not yet
Bioassay evaluation, GC-MS Analysis and Acute Toxicity Assessment of Methanolic Extracts of Trichoderma species in an Animal Model 2022-02-15 Not yet
Early zygotic gene product Dunk interacts with anillin to regulate Myosin II during Drosophila cleavage 2022-02-15 Not yet
Osteocalcin binds to the GPRC6A Venus fly trap allosteric site to positively modulate GPRC6A signaling 2022-02-15 Not yet
Highly efficient generation of isogenic pluripotent stem cell models using prime editing 2022-02-15 Not yet
Engineering Agrobacterium tumefaciens adhesion to target cells. 2022-02-15 Not yet
Sympathetic blockage attenuates fasting-induced hepatic steatosis 2022-02-15 Not yet
Super-resolution analyzing spatial organization of lysosomes with an organic fluorescent probe 2022-02-15 Not yet
Monoacylglycerol O-acyltransferase 1 is required for adipocyte differentiation in vitro but does not affect adiposity in mice 2022-02-15 Not yet
A global lipid map reveals host dependency factors conserved across SARS-CoV-2 variants 2022-02-15 Not yet
The interplay between sulfur metabolism and desulfurization profile in Rhodococcus: Unraveling the role of the transsulfuration pathway 2022-02-15 Not yet
NaCl Triggers the Sessile-to-Motile Transition of Bacillus subtilis 2022-02-15 Not yet
The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylatedIgG1 in naive but not antigen-experienced vaccinees 2022-02-15 Not yet
OsIRO3 negatively regulates Fe homeostasis by repressing the expression of OsIRO2 2022-02-15 Not yet
Nitric oxide negatively regulates gibberellin signaling to coordinate growth and salt tolerance in Arabidopsis 2022-02-15 Not yet
Dexamethasone Inhibits Cytokine-Induced, DUOX2-Related VEGF-A Expression and DNA damage in Human Pancreatic Cancer Cells and Growth of Pancreatic Cancer Xenografts 2022-02-15 Not yet
scShapes: A statistical framework for identifying distribution shapes in single-cell RNA-sequencing data 2022-02-15 Not yet
Population based selection shapes the T cell receptor repertoire during thymic development 2022-02-15 Not yet
SARS-CoV-2-specific T cells associate with reduced lung function and inflammation in pulmonary post-acute sequalae of SARS-CoV-2 2022-02-15 Not yet
Loss of Neurodevelopmental Gene CASK Disrupts Neural Connectivity in Human Cortical Excitatory Neurons 2022-02-15 Not yet
Acai (Euterpe oleracea Mart) modulates oxidative stress and inflammation by NF-κB inactivation and Nrf2 up-regulation in experimental diabetes 2022-02-14 Not yet
Functional characterization of a neuropeptide receptor exogenously expressed in Aplysia neurons 2022-02-14 Not yet
Constitutively active STAT5b feminizes mouse liver gene expression 2022-02-14 Not yet
Genomic profiling of HIV-1 integration in microglia links viral insertions to TAD organization 2022-02-14 Not yet
STING1 activation in brain endothelium by Plasmodium-sequestered heme leads to lethal cerebral malaria through activation of type I IFN response. 2022-02-14 Not yet
The chemokine receptor CXCR3 promotes CD8+ T cell-dependent lung pathology during influenza pathogenesis 2022-02-14 Not yet
Structure and mechanism of the tripartite ATP-independent periplasmic (TRAP) transporter 2022-02-14 Not yet
An arginase 2 promoter transgenic illuminates anti-inflammatory signalling in zebrafish 2022-02-14 Not yet
Protein undernutrition reduces the efficacy of praziquantel in a murine model of Schistosoma mansoni infection 2022-02-14 Not yet
Characterisation and sequence mapping of large RNA and mRNA therapeutics using mass spectrometry 2022-02-14 Not yet
The impact of the soluble protein fraction and kernel hardness on wheat flour starch digestibility 2022-02-14 Not yet
Biosynthesis of aurodox, a Type III secretion system inhibitor from Streptomyces goldiniensis 2022-02-14 Not yet
A screen of drug-like molecules identifies chemically diverse electron transport chain inhibitors in apicomplexan parasites 2022-02-14 Not yet
Identification of a novel interaction between Theileria Prohibitin (TaPHB-1) and bovine RUVBL-1 2022-02-14 Not yet
RABL2 Regulates Ciliation via Controlling IFT-B1 Basal Body Recruitment and ARL3-mediated BBSome Ciliary Retrieval 2022-02-14 Not yet
Daam1 negatively regulates USP10 activity 2022-02-14 Not yet
Lack of evidence for participation of TMEM150c/TENTONIN3 in sensory mechanotransduction. 2022-02-14 Not yet
Ultrahigh-throughput directed evolution of a metal-free α/β-hydrolase with a Cys-His-Asp triad into an efficient phosphotriesterase 2022-02-14 Not yet
Solution structure of the phosphatidylinositol 3-phosphate binding domain from the Legionella effector SetA 2022-02-14 Not yet
Joint structural annotation of small molecules using liquid chromatography retention order and tandem mass spectrometry data 2022-02-14 Not yet
Functional MRI reveals memories of mother in newborn chicks 2022-02-14 Not yet
Learning vs. minding: How subjective costs can mask motor learning 2022-02-14 Not yet
The OncoLoop network-based precision oncology framework 2022-02-14 Not yet
Navigation of Ultrasound-controlled Swarmbots under Physiological Flow Conditions 2022-02-14 Not yet
DNA-functionalized Gold Nanorods for Targeted Triple-modal Optical Imaging and Photothermal Therapy of Triple-negative Breast Cancer 2022-02-14 Not yet
Positional Context of Myonuclear Transcription during Injury-induced Muscle Regeneration 2022-02-14 Not yet
The Genetics of Participation: Method and Analysis 2022-02-14 Not yet
Polymorphic ribonucleoprotein folding as a basis for translational regulation 2022-02-12 Not yet
Improved Predictions Of MHC-Peptide Binding Using Protein Language Models 2022-02-12 Not yet
Why FIT and bHLH Ib interdependently regulate Fe-uptake 2022-02-13 Not yet
Sequence-based Functional Metagenomics Reveals Novel Natural Diversity of Functioning CopA in Environmental Microbiomes 2022-02-12 Not yet
Enhanced Sodium Channel Inactivation by Temperature and FHF2 Deficiency Blocks Heat Nociception 2022-02-13 Not yet
Non-destructive chemical sensing within bulk soil using 1000 biosensors per gram of matrix 2022-02-12 Not yet
Conifer leaves have a peroxisomal oxidative decarboxylation path in the photorespiratory pathway 2022-02-13 Not yet
Molecular signature of RV cardiac remodeling associated with Polymerase Gamma mutation 2022-02-12 Not yet
Cryo-EM structures reveal ubiquinone-10 binding to mitochondrial complex I and conformational transitions associated with Q-site occupancy 2022-02-12 Not yet
Selection of Synthetic Proteins to Modulate the Human Frataxin Function 2022-02-12 Not yet
Single Cell Proteomics Using a Trapped Ion Mobility Time-of-Flight Mass Spectrometer Provides Insight into the Post-translational Modification Landscape of Individual Human Cells 2022-02-12 Not yet
Two-pore channel blockade by phosphoinositide kinase inhibitors YM201636 and PI-103 determined by a histidine residue near pore-entrance 2022-02-12 Not yet
Plcg2M28L interacts with high fat-high sugar diet to accelerate Alzheimers disease-relevant phenotypes in mice 2022-02-12 Not yet
Induction of senescence upon loss of the Ash2l core subunit of H3K4 methyltransferase complexes 2022-02-11 Not yet
An in vivo model of echovirus-induced meningitis in neonates 2022-02-11 Not yet
ATAC-Seq and RNA-Seq combined analysis elucidates the impact of BORIS/CTCFL on melanoma progression, mediated by chromatin accessibility and gene expression alterations 2022-02-11 Not yet
Extensive in vitro and in vivo protein translation via in situ circularized RNAs 2022-02-11 Not yet
Tumor elimination by clustered microRNAs miR-306 and miR-79 via non-canonical activation of JNK signaling 2022-02-11 Not yet
Local structural dynamics of alpha-synuclein correlate with aggregation in different physiological conditions 2022-02-11 Not yet
Two bridgehead invasions of Xylella fastidiosa subsp. multiplex in France 2022-02-11 Not yet
Antisense oligonucleotides targeting exon 11 are able to partially rescue the Neurofibromatosis Type 2 phenotype in vitro 2022-02-11 Not yet
Optimal routing to cerebellum-like structures 2022-02-11 Not yet
Rapid design and prototyping of biocatalytic virus-like particle nanoreactors 2022-02-11 Not yet
A network-based drug repurposing approach identifies new treatment opportunities for the systemic chronic inflammation underlying multiple complex diseases 2022-02-11 Not yet
The First Inhibitor of Meso-Diaminopimelate Biosynthesis with Antibacterial Activity Against Multi-Drug Resistant Bacteria 2022-02-11 Not yet
Restriction of dietary protein in rats increases progressive-ratio motivation for protein 2022-02-11 Not yet
Barrier-free liquid condensates of nanocatalysts as effective concentrators of catalysis 2022-02-11 Not yet
Photolabile curcumin with physically and molecularly produced light for attenuating of neurotoxicity of amyloid beta species 2022-02-11 Not yet
PP1 inhibitor-2 promotes PP1γ positive regulation of synaptic transmission 2022-02-11 Not yet
Novel AlphasynucleinPAN in human Mesenchymal Stem Cells-derived neurons masks SNCA140 and creates dissociation of deleterious SNCA98 in astrocytoma stem cells 2022-02-11 Not yet
Orchestration of Chlorophyll and Carotenoid Biosynthesis by ORANGE Family Proteins in Plant 2022-02-11 Not yet
Chronic Intermittent Hypobaric Hypoxia Prevents Contrast-Induced Acute Kidney Injury By Modulating The HIF-1α Signaling Pathway 2022-02-11 Not yet
Omission responses in field potentials but not spikes in rat auditory cortex 2022-02-11 Not yet
Dual Inhibition of Cathepsin L and 3CL-Pro by GC-376 Constrains SARS Cov2 Infection Including Omicron Variant 2022-02-10 Not yet
Digital twin reveals combinatorial code of non-linear computations in the mouse primary visual cortex 2022-02-10 Not yet
Gi/o protein-coupled receptor inhibition of beta-cell electrical excitability and insulin secretion depends on Na+/K+ ATPase activation 2022-02-10 Not yet
Histone H4K20 Trimethylation is Decreased in Murine Models of Heart Disease 2022-02-10 Not yet
Fentanyl reinstatement to discriminative cues after conflict in sign- and goal-tracking rats 2022-02-10 Not yet
Cortical neuronal differentiation is not impaired by elevated levels of α-synuclein in human pluripotent stem cells 2022-02-10 Not yet
Simultaneous therapeutic targeting of inflammation and virus ameliorates influenza pneumonia and protects from morbidity and mortality 2022-02-10 Not yet
A conserved biosynthetic gene cluster is regulated by quorum sensing in a shipworm symbiont 2022-02-10 Not yet
The regulatory protein ChuP connects heme and siderophore-mediated iron acquisition systems required for Chromobacterium violaceum virulence 2022-02-10 Not yet
Structural basis of human IL-18 sequestration by the decoy receptor IL-18 binding protein (IL-18BP) in inflammation and tumor immunity 2022-02-10 Not yet
Rhamnan Sulfate Reduces Atherosclerotic Plaque Formation and Vascular Inflammation 2022-02-10 Not yet
Protein binding and differential distribution of calcitonin in the sub-compartments of blood: An In vitro study 2022-02-10 Not yet
Reducing Cholesterol in Resting Macrophage Activates NF-kB through Mitochondria, Resulting in Epigenomic Reprogramming to Dampen Inflammation in Activated Macrophages 2022-02-10 Not yet
OzTracs: Optical Osmolality Reporters Engineered from Mechanosensitive Ion Channels 2022-02-10 Not yet
CD8 T Cell Memory Inflation is Driven by Latent CMV Infection of Lymphatic Endothelial Cells 2022-02-10 Not yet
A pair of isoleucyl-tRNA synthetases in Bacilli fulfill complementary roles to enhance fitness and provide antibiotic resistance 2022-02-10 Not yet
A pore-forming β-trefoil lectin with specificity for the tumor-related glycosphingolipid Gb3 2022-02-10 Not yet
Nutrient-dependent regulation of β-cell KATP channels is controlled by the isoforms of pyruvate kinase and the source of phosphoenolpyruvate 2022-02-10 Not yet
Inducible Nitric Oxide Synthase deficiency leads to early demyelination by altering the balance between pro- and anti-inflammatory responses against Murine-β-Coronavirus 2022-02-10 Not yet
A Novel congenic Mouse Model to study Obesity, Diabetes and NAFLD 2022-02-10 Not yet
Linear DNA amplicons as a novel cancer vaccine strategy 2022-02-10 Not yet
Rose flavor compound β-damascone regulates dendritic cell-mediated immunoresponses by modulating the NRF2 pathway and ameliorates contact hypersensitivity 2022-02-10 Not yet
Recapitulation of Human Pathophysiology and Identification of Forensic Biomarkers in a Translational Swine Model of Chlorine Inhalation Injury 2022-02-10 Not yet
Single-cell molecular characterization to partition the human glioblastoma tumor microenvironment (TME) genetic background 2022-02-10 Not yet
The guardian of the genome meets a viral master gene regulator at a biomolecular condensate 2022-02-10 Not yet
Multinuclear MRI reveals early efficacy of stem cell therapy in stroke 2022-02-10 Not yet
High sorbic acid resistance of Penicillium roqueforti is mediated by the SORBUS gene cluster 2022-02-10 Not yet
Actin remodelling controls proteasome homeostasis upon stress 2022-02-10 Not yet
Express detection and discrimination of visual objects by primate superior colliculus neurons 2022-02-10 Not yet
Not all noise-reduction methods for fMRI preprocessing are created equal 2022-02-10 Not yet
Differential CO2-fixation potentials and supporting roles of phagotrophy and proton pump among plankton lineages in a subtropical marginal sea 2022-02-10 Not yet
A Sulfonated Thermoresponsive Injectable Gel for Sequential Release of Therapeutic Proteins to Protect Cardiac Function After a Myocardial Infarction 2022-02-10 Not yet
In-shoe plantar pressure depends on walking speed and type of weight-bearing activity in people with diabetes at high risk of ulceration 2022-02-10 Not yet
Arginine-rich C9ORF72 ALS proteins stall ribosomes in a manner distinct from a canonical ribosome-associated quality control substrate 2022-02-10 Not yet
A historically balanced locus under recent directional selection in responding to changed nitrogen conditions during modern maize breeding 2022-02-10 Not yet
Generating Functional Cells Through Enhanced Interspecies Chimerism with Human Pluripotent Stem Cells 2022-02-10 Not yet
Examination of rickettsial host range for shuttle vectors based on dnaA and parA genes from the pRM plasmid of Rickettsia monacensis 2022-02-10 Not yet
Functionally competent CD4+ T cells express high levels of T-bet in Plasmodium chabaudi infected young mice 2022-02-10 Not yet
Selective integration of diverse taste inputs within a single taste modality 2022-02-10 Not yet
Unbiased stereologic estimates of dopaminergic and GABAergic neurons in the A10, A9, and A8 subpopulations in the young male Macaque 2022-02-10 Not yet
Behavioral decomposition reveals rich encoding structure employed across neocortex 2022-02-10 Not yet
Reduced Hippocampal-Cortical Connectivity During Memory Suppression Predicts the Ability to Forget Unwanted Memories 2022-02-10 Not yet
TEMPRANILLO homologs in apple regulate flowering time in the woodland strawberry Fragaria vesca 2022-02-10 Not yet
Continuous two-phase in vitro co-culture model of the enthesis 2022-02-10 Not yet
Pathogen prevalence modulates medication behavior in ant Formica fusca 2022-02-10 Not yet
Genome-wide analyses of PAM-relaxed Cas9 genome editors reveal substantial off-target effects by ABE8e in rice 2022-02-10 Not yet
Combinatorial effects on gene expression at the Lbx1/Fgf8 locus resolve Split-Hand/Foot Malformation type 3 2022-02-10 Not yet
The Requirement of Ubiquitin C-Terminal Hydrolase L1 (UCHL1) in Mouse Ovarian Development and Fertility 2022-02-10 Not yet
Keap1 moderates the transcription of virus induced genes through G9a-GLP and NFκB p50 recruitment, and H3K9me2 deposition 2022-02-10 Not yet
An Optrode Array for Spatiotemporally Precise Large-Scale Optogenetic Stimulation of Deep Cortical Layers in Non-human Primates 2022-02-10 Not yet
Transient oscillations of neural firing rate associated with routing of evidence in a perceptual decision 2022-02-10 Not yet
A systems biology approach to elucidate the post-translational regulome of coronary artery disease 2022-02-10 Not yet
PDR6-mediated camalexin efflux and disease resistance are regulated through direct phosphorylation by the kinases OXI1 and AGC2-2 2022-02-10 Not yet
Using cGMP analogues to modulate photoreceptor light sensitivity: Perspectives for the treatment of retinal degeneration. 2022-02-10 Not yet
An Analysis of Protein Language Model Embeddings for Fold Prediction 2022-02-10 Not yet
A simple DLP-bioprinting strategy produces cell-laden crypt-villous structures for an advanced 3D gut model 2022-02-10 Not yet
Genome-wide profiling of histone H3K4me3 and H3K27me3 modifications in individual blastocysts by CUT&Tag without a solid support (NON-TiE-UP CUT&Tag) 2022-02-10 Not yet
Semantic overlap protects from interference by restoring encoding mechanisms 2022-02-10 Not yet
Conservative Significance Testing of Tripartite Interactions in Multivariate Neural Data 2022-02-10 Not yet
Looming stimuli reliably drive innate, but not learned, defensive responses in rats. 2022-02-10 Not yet
Transcriptional regulation and chromatin architecture maintenance are decoupled modular functions at the Sox2 locus 2022-02-10 Not yet
Statistical learning is not error-driven 2022-02-10 Not yet
Multistep loading of PCNA onto DNA by RFC 2022-02-09 Not yet
Membrane binding of pore-forming γ-hemolysin components studied at different lipid compositions 2022-02-09 Not yet
A catalytic mechanism for Renilla-type bioluminescence 2022-02-09 Not yet
A Multiscale study of phosphorylcholine driven cellular phenotypic targeting 2022-02-09 Not yet
Isocitrate dehydrogenase 3b is required for spermiogenesis but dispensable for retinal degeneration 2022-02-09 Not yet
Validation of a colorimetric LAMP to detect Loxosceles experimental envenomation 2022-02-09 Not yet
Disrupted development and altered hormone signaling in male Padi2/Padi4 double knockout mice 2022-02-09 Not yet
Enhanced production of antiviral dsRNA in the Chlamydomonas reinhardtii chloroplast via a novel convergent promoter expression system 2022-02-09 Not yet
N-acylethanolamine acid amide hydrolase is a novel target for drugs against SARS-CoV-2 and Zika virus 2022-02-09 Not yet
SARS-CoV-2 ORF6 disrupts innate immune signalling by inhibiting cellular mRNA export 2022-02-09 Not yet
A phasevarion controls multiple virulence traits, including expression of vaccine candidates, in Streptococcus pneumoniae 2022-02-09 Not yet
Olverembatinib inhibits SARS-CoV-2-Omicron variant-mediated cytokine release 2022-02-09 Not yet
The mechanism of RNA capping by SARS-CoV-2 2022-02-09 Not yet
Anatomical connectivity profile development constrains medial-lateral topography in the dorsal prefrontal cortex 2022-02-09 Not yet
Fate tracing reveals differences between Reelin+ HSCs and Desmin+ HSCs in activation, migration, and proliferation activities 2022-02-09 Not yet
CameraTrapDetectoR: Automatically detect, classify, and count animals in camera trap images using artificial intelligence 2022-02-09 Not yet
Neutrophils degranulate GAG-containing proteoglycofili, which block Shigella growth and degrade virulence factors 2022-02-09 Not yet
Coupling comprehensive pesticide-wide association study to iPSC dopaminergic screening identifies and classifies Parkinson-relevant pesticides 2022-02-09 Not yet
Sub-10 nm fluorescence imaging 2022-02-09 Not yet
Live cell biosensors based on the fluorescence lifetime of environment-sensing dyes 2022-02-09 Not yet
Perception of RNA Nanotechnology among students and recommendations towards improved educational outreach 2022-02-09 Not yet
Partitioning variance in reproductive success, within years and across lifetimes 2022-02-09 Not yet
Leukotrienes promote stem cell self-renewal and chemoresistance in acute myeloid leukemia 2022-02-08 Not yet
The influence of biological and statistical properties of CpGs on epigenetic predictions of eighteen traits 2022-02-08 Not yet
Proteomics profiling reveals regulation of immune response to Salmonella Typhimurium infection in mice 2022-02-08 Not yet
Hyperoxia improves repeated-sprint ability and the associated training load in athletes 2022-02-08 Not yet
The C-terminal domain of Hsp70 is responsible for paralog-specific regulation of ribonucleotide reductase 2022-02-08 Not yet
A transcription factor and a phosphatase regulate temperature-dependent morphogenesis in a fungal plant pathogen 2022-02-08 Not yet
Multi-excitation Raman Spectroscopy Complements Whole Genome Sequencing for Rapid Detection of Bacterial Infection and Resistance in WHO Priority Pathogens 2022-02-08 Not yet
Transcriptome Mining Reveals a Spectrum of RNA Viruses in Primitive Plants 2022-02-08 Not yet
Ehrlichia SLiM ligand mimetic activates Hedgehog signaling to engage a BCL-2 anti-apoptotic cellular program 2022-02-08 Not yet
Spike Protein-independent Attenuation of SARS-CoV-2 Omicron Variant in Laboratory Mice 2022-02-08 Not yet
Antiviral DExD/H-box helicase 60 selectively inhibits translation from type II internal ribosome entry sites 2022-02-08 Not yet
Neuroaffective profiles are associated with e-cigarette use 2022-02-08 Not yet
The genetics of specific cognitive abilities 2022-02-08 Not yet
Disentangling the molecular mechanisms underlying the retrieval and extinction of morphine withdrawal-associated memories in the basolateral amygdala and dentate gyrus. 2022-02-08 Not yet
High Fat Diet Blunts Stress-Induced Hypophagia and Activation of Glp1r Dorsal Lateral Septum Neurons in Male but not in Female Mice 2022-02-08 Not yet
Pre-B cell receptor acts as a selectivity switch for Galectin-1 at the pre-B cell surface 2022-02-08 Not yet
Preclinical Pharmacokinetics and In Vitro Properties of GS-441524, A Potential Oral Drug Candidate for COVID-19 Treatment 2022-02-07 Not yet
Biologically informed deep learning to infer gene program activity in single cells 2022-02-07 Not yet
Discovery of integrons in Archaea: platforms for cross-domain gene transfer 2022-02-07 Not yet
Lipid network and moiety analyses reveal enzymatic dysregulation and altered mechanisms from lipidomics 2022-02-07 Not yet
Identification of functional Spo0A residues critical for sporulation in Clostridioides difficile 2022-02-07 Not yet
Ruminococcus bromii enables the growth of proximal Bacteroides thetaiotaomicron by releasing glucose during starch degradation 2022-02-07 Not yet
Enterovirus replication and dissemination are differentially controlled by type I and III interferons in the GI tract 2022-02-07 Not yet
Feedback regulation of RNase E during UV-stress response in the cyanobacterium Synechocystis sp. PCC 6803 2022-02-07 Not yet
Theta band-power shapes amyloid-driven longitudinal EEG changes in pre-clinical Alzheimer's Disease 2022-02-07 Not yet
Apremilast prevents blistering in human epidermis by stabilization of keratinocyte adhesion in pemphigus. 2022-02-07 Not yet
A transcytotic actin shift polarizes vesicle trajectories and partitions apicobasal epithelial membrane domains 2022-02-07 Not yet
Cell-type specific transcriptional networks in root xylem adjacent cell layers 2022-02-06 Not yet
Targeted nanocarriers coopting pulmonary leukocytes for drug delivery to the injured brain 2022-02-06 Not yet
Complex genotype-phenotype relationships shape the response to treatment of Down Syndrome Childhood Acute Lymphoblastic Leukaemia 2022-02-06 Not yet
Local extensional flows promote long-range fiber alignment in 3D collagen hydrogels 2022-02-06 Not yet
Non-essential tRNA and rRNA modifications impact the bacterial response to sub-MIC antibiotic stress 2022-02-06 Not yet
Ventral pallidum GABA neurons bidirectionally control opioid relapse across rat behavioral models 2022-02-06 Not yet
Janus Kinase 3 phosphorylation and the JAK/STAT pathway are positively modulated by follicle-stimulating hormone (FSH) in bovine granulosa cells. 2022-02-06 Not yet
Interference with lipoprotein maturation sensitizes methicillin-resistant Staphylococcus aureus to human group IIA secreted phospholipase A2 and daptomycin. 2022-02-06 Not yet
Tau seeding without tauopathy 2022-02-06 Not yet
Multiscale model of primary motor cortex circuits reproduces in vivo cell type-specific dynamics associated with behavior 2022-02-06 Not yet
An improved MS2-MCP imaging system with minimal perturbation of mRNA stability 2022-02-06 Not yet
Preferential activation of proprioceptive and cutaneous sensory fibers compared to motor fibers during cervical transcutaneous spinal cord stimulation: A computational study 2022-02-06 Not yet
Interference of Neuronal TrkB Signaling by the Cannabis-Derived Flavonoids Cannflavins A and B 2022-02-06 Not yet
Distinct mechanisms of germ cell factor regulation for an inductive germ cell fate 2022-02-06 Not yet
Chlamydomonas RABL4/IFT27 Mediates Phototaxis via Promoting BBSome-dependent Ciliary Export of Phospholipase D 2022-02-06 Not yet
Insights in the complex DegU, DegS, Spo0A regulation system of Paenibacillus polymyxa by CRISPR-Cas9-based targeted point mutations 2022-02-06 Not yet
Chronic Alcohol Consumption Alters Home-Cage Behaviors and Responses to Ethologically Relevant Predator Tasks in Mice 2022-02-06 Not yet
The conserved Pelado/ZSWIM8 protein regulates actin dynamics by promoting linear actin filament polymerization 2022-02-05 Not yet
Multiple mechanisms mediate the suppression of motion vision during escape maneuvers in flying Drosophila. 2022-02-05 Not yet
Genomic prediction with whole-genome sequence data in intensely selected pig lines 2022-02-05 Not yet
Evidence for evolutionary adaptation of mixotrophic nanoflagellates to warmer temperatures 2022-02-05 Not yet
Comparative small RNA and degradome sequencing provide new insights into antagonistic interactions in the biocontrol fungus Clonostachys rosea 2022-02-05 Not yet
Interaction of an α-synuclein epitope with HLA-DRB1*15:01 initiates early enteric features of Parkinson's disease in humanized mice 2022-02-05 Not yet
Whole-Brain Map of Top-down afferent Inputs to Nucleus Accumbens of the Mouse 2022-02-05 Not yet
A scalable pipeline for SARS-CoV-2 replicon construction based on de-novo synthesis 2022-02-05 Not yet
Rtt105 configurationally staples RPA and blocks facilitated exchange and interactions with RPA-interacting proteins 2022-02-05 Not yet
Monotreme-specific conserved proteins derived from retroviral reverse transcriptase 2022-02-05 Not yet
Endothelial beta-arrestins Regulate Mechanotransduction by the Type II Bone Morphogenetic Protein Receptor in Primary Cilia 2022-02-05 Not yet
Understanding the Separation of Timescales in Rhodococcus erythropolis Proteasome Core Particle Assembly 2022-02-05 Not yet
A novel 5' DNA binding site in RFC facilitates PCNA loading for gap DNA repair 2022-02-05 Not yet
Ambra1 haploinsufficiency results in metabolic alterations and exacerbates age-associated retinal degeneration 2022-02-05 Not yet
Habitat Suitability Modeling and Ecological Forecasting of Northern Goshawk Nesting Habitat 2022-02-04 Not yet
Monitoring conservation effectiveness in tropical forests: bushmeat offtake parameters vary more quickly compared to parameters related to the living wildlife community 2022-02-04 Not yet
Effect of compound Tinglizi Decoction on non-classical pathway of pyroptosis in rats with chronic obstructive pulmonary disease related pulmonary hypertension 2022-02-04 Not yet
Single cell transcriptomic and spatial landscapes of the developing human pancreas 2022-02-04 Not yet
Air pollution induces Staphylococcus aureus USA300 respiratory tract colonisation mediated by specific bacterial genetic responses dependent on the global virulence gene regulators Agr and Sae 2022-02-04 Not yet
Inactivating Mast Cell Function Promotes Steady-State and Regenerative Hematopoiesis 2022-02-04 Not yet
Minimal RNA replicons for targeted gene silencing based on an asymptomatic viroid 2022-02-04 Not yet
AAA+ protease-adaptor structures reveal altered conformations and ring specialization 2022-02-04 Not yet
Chimeric a-subunit isoforms generate functional yeast V-ATPases with altered regulatory properties in vitro and in vivo 2022-02-04 Not yet
ZNF598 responds to mitochondrial stress to abort stalled translation on mitochondrial outer membrane and maintain tissue homeostasis 2022-02-04 Not yet
Type B and Type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD 2022-02-04 Not yet
Re-sensitising XDR biofilms using a combination of bacteriophage cocktails and colistin: a natural approach 2022-02-04 Not yet
Circulatory exosomes from COVID-19 patients trigger NLRP3 inflammasome in endothelial cells 2022-02-04 Not yet
Corticospinal excitability is influenced by the recent history of electrical digital stimulation: implications for the relative magnitude of short-latency afferent inhibition 2022-02-04 Not yet
Taurine or N-acetylcysteine treatments prevent memory impairment and metabolite profile alterations in the hippocampus of high-fat diet-fed female mice 2022-02-04 Not yet
Human orbitofrontal cortex signals decision outcomes to sensory cortex during behavioural adaptations 2022-02-04 Not yet
A novel hidden Markov approach to studying dynamic functional connectivity states in human neuroimaging 2022-02-04 Not yet
Artificial soils reveal individual factor controls on microbial processes 2022-02-04 Not yet
Single-Cell Transcriptome Analysis Identifies Novel Biomarkers Involved in Major Liver Cancer Subtypes 2022-02-04 Not yet
mRNA-1273 or mRNA-Omicron boost in vaccinated macaques elicits comparable B cell expansion, neutralizing antibodies and protection against Omicron 2022-02-04 Not yet
Modulation of stress-related behaviour by hypothalamic engagement of preproglucagon neurons in the nucleus of the solitary tract 2022-02-04 Not yet
ABA signaling prevents phosphodegradation of the Arabidopsis SR45 splicing factor to negatively autoregulate inhibition of early seedling development 2022-02-04 Not yet
De novo stem cell establishment in meristems requires repression of organ boundary cell fate 2022-02-04 Not yet
Maternal Wnt11b regulates cortical rotation during Xenopus axis formation: analysis of maternal-effect wnt11b mutants 2022-02-04 Not yet
Canonical BMP2/4 signaling degrades SOX2 in glioblastoma propagating cells. 2022-02-04 Not yet
Peptide-based drug predictions for cancer therapy using deep learning 2022-02-04 Not yet
Novel plasma exosome biomarkers for prostate cancer progression in co-morbid metabolic disease 2022-02-04 Not yet
Augmented efficacy of uttroside B over sorafenib in a murine model of human hepatocellular carcinoma 2022-02-04 Not yet
Perivascular macrophages collaborate to facilitate chemotherapy resistance in cancer 2022-02-04 Not yet
Perilipin 5 interacts with Fatp4 at membrane contact sites to promote lipid droplet-to-mitochondria fatty acid transport 2022-02-03 Not yet
SdiA, a Quorum Sensing Transcriptional Regulator, Enhanced the Drug Resistance of Cronobacter sakazakiiand Suppressed its Motility, Adhesion and Biofilm Formation 2022-02-03 Not yet
Therapeutic vulnerability to ATR inhibition in concurrent NF1 and ATRX-deficient high-grade solid tumors 2022-02-03 Not yet
Meis1 supports leukemogenesis through stimulation of ribosomal biogenesis and Myc 2022-02-03 Not yet
Activating ligands of Uncoupling protein 1 identified by rapid membrane protein thermostability shift analysis 2022-02-03 Not yet
2'-O-methylation of the second transcribed nucleotide within mRNA 5' cap impacts protein production level in a cell specific manner and contributes to RNA immune evasion 2022-02-03 Not yet
Enhancing high-temperature degradation of polyethylene terephthalate through a synergistic division of enzyme labour between a solid-degrading thermostable cutinase and a reaction intermediate-degrading thermostable ... 2022-02-03 Not yet
Exploring the lncRNA localization landscape within the retinal pigment epithelium under normal and stress conditions 2022-02-03 Not yet
Comprehensive comparison between azacytidine and decitabine treatment in an acute myeloid leukemia cell line 2022-02-03 Not yet
Rapid aggregation of Staphylococcus aureus in synovial fluid is influenced by synovial fluid concentration, viscosity, and fluid dynamics-with evidence of polymer bridging 2022-02-03 Not yet
COVID-19 infection enhances susceptibility to oxidative-stress induced parkinsonism 2022-02-03 Not yet
Beyond G1/S regulation: how cell size homeostasis is tightly controlled throughout the cell cycle? 2022-02-03 Not yet
Sex and age differences in cognitive bias and neural activation in response to cognitive bias 2022-02-03 Not yet
Dissociable Roles of FEF Neurons in Initiating Saccades 2022-02-03 Not yet
A Spiking Neural Network Model of Rodent Head Direction calibrated with Landmark Free Learning. 2022-02-03 Not yet
IZUMO1 is a sperm fusogen 2022-02-03 Not yet
Nucleation of the destruction complex on the centrosome accelerates degradation of β-catenin and regulates Wnt signal transmission 2022-02-03 Not yet
Molecular mechanics underlying flat-to-round membrane budding in live secretory cells 2022-02-03 Not yet
Distinct silencer states determine epigenetic states of heterochromatin 2022-02-03 Not yet
Recruitment of transcriptional effectors by Cas9 creates cis regulatory elements and demonstrates distance-dependent transcriptional regulation 2022-02-03 Not yet
Synthetic genetic circuits enable reprogramming of plant roots 2022-02-03 Not yet
SRSF1 as a novel interacting partner for IFITM1/3 unravels the emergent role of IFITM1/3 mediating protein expression 2022-02-03 Not yet
Behavioural analysis of loss of function zebrafish supports baz1b as master regulator of domestication 2022-02-03 Not yet
InvL, an invasin-like adhesin, is a type II secretion system substrate required for Acinetobacter baumannii uropathogenesis. 2022-02-03 Not yet
6S RNA-dependent antibiotic susceptibility 2022-02-03 Not yet
Bile Salts and N-Acetyl-D-Glucosamine induce transcription of the vieSAB Operon in Vibrio cholerae El Tor 2022-02-02 Not yet
Genomic and phenotypic analyses suggest moderate fitness differences among Zika virus lineages 2022-02-02 Not yet
Breasi-CRISPR: an efficient genome editing method to interrogate protein localization and protein-protein interactions in the embryonic mouse cortex 2022-02-02 Not yet
Intracellular flow cytometry complements RT-qPCR detection of circulating SARS-CoV-2 variants of concern 2022-02-02 Not yet
Metabolic dyshomeostasis induced by SARS-CoV-2 structural proteins reveals immunological insights into viral olfactory interactions 2022-02-02 Not yet
Chronic alcohol intake regulates expression of SARS-CoV2 infection-relevant genes in an organ-specific manner 2022-02-02 Not yet
Effects of calorie restriction on reactive oxygen species production by mitochondrial reverse electron transport, mitochondrial permeability transition pore, and beta-adrenergic stimulation during cardiac hypertrophy 2022-02-02 Not yet
Conformational transitions of the mitotic adaptor Spindly underlie its interaction with Dynein and Dynactin 2022-02-02 Not yet
USP22 controls type III interferon signaling and SARS-CoV-2 infection through activation of STING 2022-02-02 Not yet
Identifying inputs to visual projection neurons in Drosophila lobula by analyzing connectomic data 2022-02-02 Not yet
Aucubin promoted neuron functional recovery by suppressing inflammation and neuronal apoptosis in a spinal cord injury model 2022-02-02 Not yet
Neural network of superiority illusion predicts the level of dopamine in striatum 2022-02-02 Not yet
Proteomics and Functional Analysis Revealed TaGSTU6/TaCBSX3 Enhances Wheat Resistance to Powdery Mildew 2022-02-02 Not yet
3D printed bioreactor enabling the physiological culture and the study of pathological processes in large vessels. 2022-02-02 Not yet
JUN Regulation of Injury-induced Enhancers in Schwann Cells 2022-02-02 Not yet
Activity and state dependent modulation of salt taste behavior in Drosophila melanogaster 2022-02-02 Not yet
Soil amendments and suppresssion of Phytophthora root rot in avocado (Persea indica) 2022-02-02 Not yet
A New Classification Method Based on Dynamic Ensemble Selection and its Application to Predict Variance Patterns in HIV-1 Env 2022-02-02 Not yet
Embodiment of Supernumerary Robotic Limbs in Virtual Reality 2022-02-02 Not yet
GLMsingle: a toolbox for improving single-trial fMRI response estimates 2022-02-02 Not yet
A pseudotyped lentivirus-based assay to titer SARS-CoV-2 neutralizing antibodies in Mexico 2022-02-02 Not yet
Molecular mechanisms involved in Atlantic halibut (Hippoglossus hippoglossus) egg quality: impairments at transcription and protein folding levels induce inefficient protein and energy homeostasis during early development 2022-02-02 Not yet
Dissociable neural correlates of multisensory coherence and selective attention 2022-02-02 Not yet
Cilia stimulatory and antibacterial activities of bitter receptor agonist diphenhydramine: insights into potential complimentary strategies for CF nasal infections 2022-02-01 Not yet
A Deep Learning solution for triaging patient with cancer from their predicted mutational status using histopathological images 2022-02-01 Not yet
Mesenchymal stem cells support human vascular endothelial cells to form vascular sprouts in human platelet lysate-based matrices. 2022-02-01 Not yet
Understanding Chicks' Emotions: Are Eye Blinks & Facial Temperatures Reliable Indicators? 2022-02-01 Not yet
Engineering SARS-CoV-2 cocktail antibodies into a bispecific format improves neutralizing potency and breadth 2022-02-01 Not yet
Selective inhibitors of JAK1 targeting a subtype-restricted allosteric cysteine 2022-02-01 Not yet
Injectable hydrogels with phase-separated structures that can encapsulate live cells 2022-02-01 Not yet
Human immunodeficiency virus type 2 capsid protein mutagenesis defines the determinants for Gag-Gag interactions 2022-02-01 Not yet
Activation of a bacterial flow sensor by hypochlorous acid from stimulated neutrophils 2022-02-01 Not yet
HIV-2 Immature Particle Morphology Provides Insights into Gag Lattice Stability and Virus Maturation 2022-02-01 Not yet
Inadvertent Transfer of Murine VL30 Retrotransposons to CAR-T Cells. 2022-02-01 Not yet
Positive strand RNA viruses differ in the constraints they place on the folding of their negative strand 2022-02-01 Not yet
Egg-adaptation pathway of human influenza H3N2 virus is contingent on natural evolution 2022-02-01 Not yet
The lipid peroxidation product 4-hydroxynonenal inhibits NLRP3 inflammasome activation and macrophage pyroptosis 2022-02-01 Not yet
Pancreatic Tumor Eradication via Selective PIN1 Inhibition in Cancer Associated Fibroblasts and T Lymphocytes Engagement 2022-02-01 Not yet
Optimization of NLS Composition Improves CRISPR-Cas12a Editing Rates in Human Primary Cells 2022-02-01 Not yet
Epithelial uptake of Aspergillus fumigatus drives efficient fungal clearance in vivo and is aberrant in Chronic Obstructive Pulmonary Disease (COPD) 2022-02-01 Not yet
Influenza virus-like particle-based hybrid vaccine containing RBD induces immunity against influenza and SARS-CoV-2 viruses 2022-02-01 Not yet
The ABA INSENSITIVE (ABI) 4 transcription factor is stabilized by stress, ABA and phosphorylation 2022-02-01 Not yet
CMTR1 is recruited to transcription start sites and promotes ribosomal protein and histone gene expression in embryonic stem cells 2022-02-01 Not yet
Profilin 1 deficiency drives mitotic defects and impairs genome stability 2022-02-01 Not yet
Mitophagy mediates beige to white transition of human primary subcutaneous adipocytes ex vivo 2022-02-01 Not yet
Constraint-based modeling identifies metabolic vulnerabilities during the epithelial to mesenchymal transition 2022-02-01 Not yet
Histone deacetylase inhibitor induces acetyl-CoA depletion leading to lethal metabolic stress in RAS-pathway activated cells 2022-02-01 Not yet
Keratin 8 is a scaffolding and regulatory protein of ERAD complexes 2022-02-01 Not yet
Amyloid fibrils in frontotemporal lobar degeneration with TDP-43 inclusions are composed of TMEM106B, rather than TDP-43 2022-02-01 Not yet
Effects of global change on animal biodiversity in boreal forest landscape: an assemblage dissimilarity analysis 2022-02-01 Not yet
Novel Association of Lyme Disease, Age, and Atopic Dermatitis 2022-02-01 Not yet
Growth cone macropinocytosis of neurotrophin receptor and neuritogenesis are regulated by Neuron Navigator 1 2022-02-01 Not yet
The Growth Hormone Releasing Hormone Signaling Pathway Governs Cardiomyocyte differentiation in human iPS cells. 2022-01-31 Not yet
Analysis of secondary metabolite gene clusters and chitin biosynthesis pathways of Monascus purpureus with high production of pigment and citrinin based on whole-genome sequencing 2022-01-31 Not yet
Extracellular vesicle microRNA cargo engineering reveals critical mechanisms underlying therapeutic efficacy 2022-01-31 Not yet
Non-canonical scaffold-type ligase complex mediates protein UFMylation 2022-01-31 Not yet
Revisiting degron motifs in human AURKA required for its targeting by APC/C-FZR1 2022-01-31 Not yet
Selective inhibition of protein secretion by abrogating receptor-coat interactions during ER export. 2022-01-31 Not yet
In vitro direct regeneration and Agrobacterium tumefaciens mediated in planta transformation of Ocimum sanctum L. 2022-01-31 Not yet
Evaluation of PRKACA as a Therapeutic Target for Fibrolamellar Carcinoma 2022-01-31 Not yet
Pseudotime analysis reveals novel regulatory factors for multigenic onset and monogenic transition of odorant receptor expression 2022-01-31 Not yet
Peptide location fingerprinting identifies species- and tissue-conserved structural remodelling of proteins as a consequence of ageing and disease 2022-01-31 Not yet
A novel fully-spliced accessory gene in equine lentivirus with distinct Rev-responsive element 2022-01-31 Not yet
Chromatin-associated microprocessor assembly is regulated by PRP40, the U1 snRNP auxiliary protein 2022-01-31 Not yet
Repair of Mismatched Templates during Rad51-dependent Break-Induced Replication 2022-01-31 Not yet
Significant Broad Spectrum Antiviral activity of Bi121 Against Different Variants of SARS-CoV-2 2022-01-31 Not yet
Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human macrophages 2022-01-31 Not yet
Ornithine Lipid Activates Both TLR4 and the non-canonical NLRP3 Inflammasome. 2022-01-31 Not yet
Acyl ghrelin attenuates neurochemical and motor deficits in the 6OHDA model of Parkinsons disease 2022-01-31 Not yet
Do place cells dream of deceptive moves in a signaling game? 2022-01-31 Not yet
Impact of APOE e3 and e4 genotypes on plasma proteome signatures in Alzheimer's disease 2022-01-31 Not yet
A novel role of 3,5-cAMP in the regulation of actin cytoskeleton in Arabidopsis. 2022-01-31 Not yet
A second DNA binding site on RFC facilitates clamp loading at gapped or nicked DNA 2022-01-31 Not yet
Mechanistic insights into intramembrane proteolysis by E. coli site-2 protease homolog RseP 2022-01-31 Not yet
Spatial Venomics - Cobra Venom System Reveals Spatial Differentiation of Snake Toxins by Mass Spectrometry Imaging 2022-01-31 Not yet
Virucidal activity and mechanism of action of cetylpyridinium chloride against SARS-CoV-2 2022-01-31 Not yet
High Frequencies of PD-1+TIM3+TIGIT+CTLA4+ Functionally Exhausted SARS-CoV-2-Specific CD4+ and CD8+ T Cells Associated with Severe Disease in Critically ill COVID-19 Patients 2022-01-31 Not yet
Neural correlates of perceived emotions in human insula and amygdala 2022-01-31 Not yet
An actionable map of arm and hand muscle responses to electrical stimulation of the dorsal cervical spinal cord in humans 2022-01-31 Not yet
Visible blue light inactivates SARS-CoV-2 variants and inhibits Delta replication in differentiated human airway epithelia 2022-01-31 Not yet
Real-time neurofeedback to alter interpretations of a naturalistic narrative 2022-01-31 Not yet
Staphylococcus aureus prophages are gatekeepers of exogenous lipid utilization to control membrane flexibility and bacterial fitness 2022-01-31 Not yet
Rhythmic Cilium in SCN Neuron is a Gatekeeper for the Intrinsic Circadian Clock 2022-01-31 Not yet
A Mesenchymal Tumor Cell State Confers Increased Dependency on the BCL-XL Anti-apoptotic Protein in Kidney Cancer 2022-01-31 Not yet
RNA induces unique tau strains and stabilizes Alzheimer disease seeds 2022-01-31 Not yet
Evolution of neural activity in circuits bridging sensory and abstract knowledge 2022-01-30 Not yet
Establishment of physiologically relevant oxygen gradients in microfluidic organ chips 2022-01-30 Not yet
Targeted degradation of PCNA outperforms stoichiometric inhibition to result in programed cell death 2022-01-30 Not yet
Thyroid hormones deficiency impairs male germ cell development: a cross talk between hypothalamic-pituitary-thyroid, and - gonadal axes in zebrafish 2022-01-30 Not yet
LKB1 acts as a critical brake for the glucagon-mediated fasting response 2022-01-30 Not yet
Liver Protein Expression in NASH Mice on a High-Fat Diet 2022-01-30 Not yet
An Acyclic Phosphonate Prodrug of HPMPC is Effective Against VZV in Skin Organ Culture and Mice 2022-01-30 Not yet
Development of 3D breast cancer models with human T cells expressing engineered MAIT cell receptors 2022-01-30 Not yet
The NAD+ precursor NMN activates dSarm to trigger axon degeneration in Drosophila 2022-01-30 Not yet
A Phase-separating Thiol-ene Photoresin for Volumetric Bioprinting of Macroporous Hydrogels 2022-01-30 Not yet
Quantitative evaluation of warming and hemodilution as two techniques to increase the flow rate of blood during simulated massive transfusion of packed red blood cells 2022-01-29 Not yet
Altered meningeal immunity contributing to the autism-like behavior of BTBR T+ Itpr3tf/J mice. 2022-01-29 Not yet
Distinct genetic determinants and mechanisms of SARS-CoV-2 resistance to remdesivir 2022-01-29 Not yet
Complex and critical roles for the AtrR transcription factor in control of cyp51A expression in Aspergillus fumigatus 2022-01-29 Not yet
Transcriptome Analysis of the Nematode Caenorhabditis elegans and Litoditis marina in a Chemically Defined Food Environment 2022-01-29 Not yet
Development of an Ultra Low-Cost SSVEP-based BCI Device for Real-Time On-Device Decoding 2022-01-29 Not yet
Categorization and discrimination of human and non-human primate affective vocalizations: investigation of the frontal cortex activity through fNIRS. 2022-01-29 Not yet
An allosteric agonist activates BK channels by perturbing coupling between Ca2+ binding and pore opening 2022-01-29 Not yet
Molecular hydrogen is an overlooked energy source for marine bacteria 2022-01-29 Not yet
Lactate Signaling Mediated by AMD3100 Ameliorates Astrocyte Pathology and Remyelination Without Additional Extension of SOD1G93A Mice' Life-Span 2022-01-29 Not yet
An optimized method for the isolation of urinary extracellular vesicles for molecular phenotyping: detection of biomarkers for radiation exposure 2022-01-28 Not yet
Identification of 121 variants of honey bee Vitellogenin protein sequences with structural differences at functional sites 2022-01-28 Not yet
CRY-BARs: Versatile light-gated molecular tools for the remodeling of membrane architectures 2022-01-28 Not yet
Water-Only Look-Locker Inversion recovery (WOLLI) T1 mapping 2022-01-28 Not yet
Cryo-EM structure of RNA-induced tau fibrils reveals a small C-terminal core that may nucleate fibril formation 2022-01-28 Not yet
Nematodes can survive in a suspended form of life for indefinite time 2022-01-28 Not yet
Campylobacter jejuni induces differentiation of human neutrophils to the CD16hi/CD62Llo subtype which possess cancer promoting activities 2022-01-28 Not yet
Cerebro-cerebellar networks facilitate learning through feedback decoupling 2022-01-28 Not yet
Face processing in the infant brain after pandemic lockdown 2022-01-28 Not yet
Mechanodetection of neighbor plants elicits adaptive leaf movements through calcium dynamics 2022-01-28 Not yet
The adapted Activity-By-Contact-model for enhancer-gene assignment and its combination with transcription factor affinities in single cell data 2022-01-28 Not yet
Evaluation of P. aeruginosa attachment on mineralized collagen scaffolds and addition of manuka honey to increase mesenchymal stem cell osteogenesis 2022-01-28 Not yet
Neuroprotective effects of Canagliflozin: lessons from aged genetically diverse UM-HET3 mice. 2022-01-28 Not yet
mGluR5 PAMs rescue cortical and behavioural defects in a mouse model of CDKL5 deficiency disorder. 2022-01-28 Not yet
Probabilistic forward replay of anticipated stimulus sequences in human primary visual cortex and hippocampus 2022-01-28 Not yet
Widespread alterations in microRNA biogenesis in human Huntington's disease putamen 2022-01-28 Not yet
Decoding the temporal dynamics of affective scene processing 2022-01-28 Not yet
Antagonistic regulation of Drosophila mitochondrial uncoupling protein UCP4b by cold and BMP signaling 2022-01-28 Not yet
The Vibrio vulnificus stressosome is dispensable in nutrient-replete conditions. 2022-01-28 Not yet
mucG, mucH,and mucI modulate production of mutanocyclin and reutericyclins in Streptococcus mutans B04Sm5 2022-01-28 Not yet
Existence of blood circulating immune-cell clusters (CICs) comprising antigen-presenting cells and B cells 2022-01-28 Not yet
Self-assembled DNA nanostructures promote cell migration & differentiation of human umbilical vein endothelial cells 2022-01-28 Not yet
Genetic characterization of ABC pesticide transporters establishes Drosophila as an in vivo model for toxicogenetics 2022-01-28 Not yet
RNase L-mediated RNA decay alters 3' end formation and splicing of host mRNAs 2022-01-28 Not yet
Allatotropin in the Corpora Allata and Ovaries of Rhodnius prolixus: Probable in situ regulatory mechanisms 2022-01-28 Not yet
A Statistical Physics Approach for Disease Module Detection 2022-01-28 Not yet
A wheat kinase and immune receptor form the host-specificity barrier against the blast fungus 2022-01-28 Not yet
Knockout of OsSWEET15 impaired rice embryo formation and seed-setting 2022-01-28 Not yet
The phloem-resident protein OCTOPUS is a novel regulator of flg22-induced responses in Arabidopsis thaliana 2022-01-28 Not yet
Temperature modulates PVN pre-sympathetic neurones via transient receptor potential ion channels. 2022-01-28 Not yet
Deletion of Sod1 in motor neurons exacerbates age-related changes in axons and NMJs associated with premature muscle atrophy in aging mice 2022-01-28 Not yet
Single-Cell Analysis Identifies Distinct Immune and Smooth Muscle Cell Populations that Contribute to Chronic Thromboembolic Pulmonary Hypertension 2022-01-28 Not yet
Generation of stable microtubule superstructures by binding of peptide-fused tetrameric proteins to inside and outside 2022-01-28 Not yet
Topology of connective tissues: a key parameter in cellular heterogeneity, beyond composition and stiffness 2022-01-28 Not yet
LuminoCell: a versatile and affordable luminometer platform for monitoring in-cell luciferase-based reporters 2022-01-28 Not yet
Gnas ablation in CD11c+ cells prevents high-fat diet-induced obesity by elevating adipose tissue catecholamine levels and thermogenesis 2022-01-28 Not yet
In silico transcriptomics identifies FDA-approved drugs and biological pathways for protection against cisplatin-induced hearing loss 2022-01-28 Not yet
Methacrylate-Modified Gold Nanoparticles Enable Non-Invasive Monitoring of Photocrosslinked Hydrogel Scaffolds 2022-01-28 Not yet
Selective Ablation of 3' RNA ends and Processive RTs Facilitate Direct cDNA Sequencing of Full-length Host cell and Viral Transcripts 2022-01-28 Not yet
De novo transcriptome of Taverniera cuneifolia (Roth) Ali. 2022-01-28 Not yet
Phenotypic and transcriptomic responses of the sun- and shade-loving plants to sunlight and dim-light conditions 2022-01-28 Not yet
Convergent recruitment of Amh as the sex determination gene in two lineages of stickleback fish 2022-01-28 Not yet
KLF5-regulated extracellular matrix remodeling secures biliary epithelial tissue integrity against cholestatic liver injury 2022-01-28 Not yet
Sex-Specific Genes Identified in Sea Urchin Gonads are Expressed Prior to Metamorphosis 2022-01-28 Not yet
Cross-linked natural IntegroPectin films from Citrus biowaste with intrinsic antimicrobial activity 2022-01-28 Not yet
Development of the First Tractable Genetic System for Parvimonas micra, a Ubiquitous Pathobiont in Human Dysbiotic Disease 2022-01-28 Not yet
Fe(III)-dependent anaerobic methane-oxidizing activity in a deep underground borehole demonstrated by in-situ pressure groundwater incubation 2022-01-28 Not yet
Sensing Echoes: Temporal misalignment as the Earliest Marker of Neurodevelopmental Derail 2022-01-28 Not yet
Inflammasome mediated neuronal-microglial crosstalk: a therapeutic substrate in C9orf72-FTD/ALS. 2022-01-28 Not yet
Shared and distinct functional effects of patient-specific Tbr1 mutations on cortical development 2022-01-28 Not yet
FRIENDLY (FMT) is an RNA binding protein associated with cytosolic ribosomes at the mitochondrial surface 2022-01-28 Not yet
Dynamics of Human Serum Transferrin in Varying Physicochemical Conditions Explored by Using Molecular Dynamics Simulations 2022-01-28 Not yet
ARZIMM: A Novel Analytic Platform for the Inference of Microbial Interactions and Community Stability from Longitudinal Microbiome Study 2022-01-28 Not yet
Role of RIGI, MDA5 and interferon alpha of duck in Duck Plague infection, a novel report 2022-01-28 Not yet
Divergent Golgi Trafficking Limits B cell-Mediated IgG Sialylation 2022-01-28 Not yet
Inhibitor of the nuclear transport protein XPO1 enhances the anticancer efficacy of KRAS G12C inhibitors in preclinical models of KRAS G12C mutant cancers 2022-01-28 Not yet
Shade-induced transcription of PIF-Direct-Target Genes precedes H3K4-trimethylation chromatin modifications 2022-01-28 Not yet
A high-throughput approach to identify reproductive toxicants among environmental chemicals using an in vivo evaluation of gametogenesis in budding yeast Saccharomyces cerevisiae 2022-01-28 Not yet
A pipeline to track unlabeled cells in wide migration chambers using pseudofluorescence 2022-01-28 Not yet
Transcription factor determines the sources of extracellular vesicle DNA 2022-01-28 Not yet
AICAR-mediated selection of karyotypically normal cells in Pallister Killian syndrome patient-derived skin fibroblasts 2022-01-27 Not yet
Multi-modal and multi-subject modular organization of human brain networks 2022-01-27 Not yet
Tracking human skill learning with a hierarchical Bayesian sequence model 2022-01-27 Not yet
B-cell epitope mapping of TprC and TprD variants of Treponema pallidum subspecies 2022-01-27 Not yet
Biocompatible fluorocarbon liquid underlays for in situ extraction of isoprenoids from microbial cultures 2022-01-27 Not yet
Grandmaternal allergen exposure causes distinct epigenetic trajectories in offspring associated with airway hyperreactivity and inflammation. 2022-01-27 Not yet
A novel bacteriocin produced by Bifidobacterium longum subsp. infantis has dual antimicrobial and immunomodulatory activity 2022-01-27 Not yet
Molecular mechanisms of Plasmodium development in male and female Anopheles mosquitoes 2022-01-27 Not yet
KaiC-like proteins improve stress resistance in environmental Pseudomonas species 2022-01-27 Not yet
The IMD and JNK pathways drive the functional integration of the immune and circulatory systems of mosquitoes 2022-01-27 Not yet
Molecular insights into the MCM8/9 helicase complex in DNA unwinding and translocation 2022-01-27 Not yet
Unconventional secretion of α-synuclein mediated by palmitoylated DNAJC5 oligomers 2022-01-27 Not yet
Multivalent interactions essential for lentiviral integrase function 2022-01-27 Not yet
JQ-1 ameliorates schistosomiasis liver granuloma in mice by suppressing male and female reproductive systems and egg development of Schistosoma japonicum 2022-01-27 Not yet
Establishment and characterization of novel autologous pair primary cultures from two Indian non-habitual tongue carcinoma patients 2022-01-27 Not yet
Reversible adhesion by type IV pili leads to formation of irreversible localized clusters 2022-01-27 Not yet
CavitySpace: A database of potential ligand binding sites in the human proteome 2022-01-27 Not yet
The interferon-inducible GTPase MxB promotes capsid disassembly and genome release of herpesviruses 2022-01-27 Not yet
Essential bromodomain TcBDF2 as a drug target against Chagas disease 2022-01-27 Not yet
PIMT suppresses endothelial activation and vascular inflammation through methylation of TRAF6 2022-01-27 Not yet
A murine Wac model exhibits phenotypes relevant to DeSanto-Shinawi Syndrome 2022-01-27 Not yet
Dopamine D1-like receptor blockade and stimulation decreases operant responding for nicotine and food in male and female rats 2022-01-27 Not yet
Hijacking Methyl Reader proteins for Nuclear-Specific Protein Degradation 2022-01-27 Not yet
Entorhinal layer 6b subplate neurons govern spatial learning and memory 2022-01-27 Not yet
The way of the light: how visual information reaches the auditory cortex in congenitally deaf adults 2022-01-27 Not yet
Enhanced anticipatory biasing of visuospatial attention in deaf native-signing adults indexed by alpha-band (8-14 Hz) oscillatory neural activity 2022-01-27 Not yet
Target-dependent siRNA suppression distinguishes self from non-self endogenous siRNAs in C. elegans germline 2022-01-26 Not yet
An LTR retrotransposon in the promoter of a PsMYB10.2 gene associated with the regulation of fruit flesh color in Japanese plum 2022-01-26 Not yet
Transient RNA structures cause aberrant influenza virus replication and innate immune activation 2022-01-26 Not yet
The Third Transmembrane Domain of Synaptophysin Regulates Initial Fusion Pore Dynamics during Ca2+ -Triggered Exocytosis in Chromaffin cells 2022-01-26 Not yet
S-Acylation Regulates the Membrane Association and Activity of Calpain-5 2022-01-26 Not yet
Investigation of oxidative processes and revealing the changes in purine nucleoside phosphorylase activity levels in model animals in the development of diabetes mellitus 2022-01-26 Not yet
The Alternative Sigma Factor SigL Influences Clostridioides difficile Toxin Production, Sporulation, and Cell Surface Properties 2022-01-26 Not yet
The SARS-CoV-2 protein NSP2 impairs the microRNA-induced silencing capacity of human cells 2022-01-26 Not yet
Despite the odds: formation of the SARS-CoV-2 methylation complex. 2022-01-26 Not yet
Epigenetic Landscape of HIV Infection in Primary Human Macrophage 2022-01-26 Not yet
Phage Paride hijacks bacterial stress responses to kill dormant, antibiotic-tolerant cells 2022-01-26 Not yet
Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical stem supersite of vulnerability 2022-01-26 Not yet
The mycotoxin Beauvericin exhibits immunostimulatory effects on dendritic cells via activating the TLR4 signaling pathway 2022-01-26 Not yet
The role of the orbitofrontal cortex in creating cognitive maps 2022-01-26 Not yet
Verification of extracellular vesicle-mediated functional mRNA delivery via RNA editing 2022-01-26 Not yet
Study on gene knockout mice and human mutant individual reveals absence of CEP78 causes photoreceptor and sperm flagella impairments 2022-01-26 Not yet
Cell size homeostasis under the circadian regulation of cell division in cyanobacteria 2022-01-26 Not yet
LET-dependence of radiation-induced makers of Immunogenic Cell Death in human cancer cell lines 2022-01-26 Not yet
Multiple Ciliary Localization Signals Control INPP5E Ciliary Targeting 2022-01-26 Not yet
MX2 viral substrate breadth and inhibitory activity are regulated by protein phosphorylation 2022-01-25 Not yet
Preclinical Characterization of Relatlimab, a Human LAG-3-Blocking Antibody, Alone or in Combination With Nivolumab 2022-01-25 Not yet
Observing noncovalent interactions in experimental electron density for macromolecular systems: A novel perspective for protein-ligand interaction research 2022-01-25 Not yet
Functional and structural deficiencies of Gemin5 variants associated with neurological disease 2022-01-25 Not yet
HNRNPK is retained in the cytoplasm by Keratin 19 to stabilize target mRNAs 2022-01-25 Not yet
An efficient CRISPR-Cas9 enrichment sequencing strategy for characterizing complex and highly duplicated genomic regions. A case study in the Prunus salicina LG3-MYB10 genes cluster. 2022-01-25 Not yet
Human sialomucin CD164 is an essential entry factor for lymphocytic choriomeningitis virus 2022-01-25 Not yet
Live biotherapeutic throat spray for respiratory virus inhibition and interferon pathway induction 2022-01-25 Not yet
P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection 2022-01-25 Not yet
Structural insight into antibody evasion of SARS-CoV-2 omicron variant 2022-01-25 Not yet
Structural Ramifications of Spike Protein D614G Mutation in SARS-CoV-2 2022-01-25 Not yet
Converting non-neutralizing SARS-CoV-2 antibodies targeting conserved epitopes into broad-spectrum inhibitors through receptor blockade 2022-01-25 Not yet
Emergence of glycogen synthase kinase-3 interaction domain enhances phosphorylation of SARS-CoV-2 nucleocapsid protein 2022-01-25 Not yet
The effect of COVID-19 mRNA vaccine on respiratory system: human lung carcinoma cells by means of Raman spectroscopy and imaging. 2022-01-25 Not yet
Non-uniform dystrophin re-expression after CRISPR-mediated exon excision in the dystrophin/utrophin double-knockout mouse model of DMD 2022-01-25 Not yet
The tyrosine phosphatase PRL regulates attachment of Toxoplasma gondii to host cells and is essential for virulence 2022-01-25 Not yet
Prior exposure to speech rapidly modulates cortical processing of high-level linguistic structure 2022-01-25 Not yet
Impacts of development and adult sex on brain cell numbers in the Black Soldier Fly, Hermetia illucens L. (Diptera: Stratiomyidae) 2022-01-25 Not yet
LPS-TLR4 pathway stimulating in acute-on-chronic liver failure by promote NETs formation 2022-01-25 Not yet
Characterization and identification of a novel daidzein reductase involved in (S)-equol biosynthesis in Clostridium C1 2022-01-25 Not yet
Biodiversity of the Genus Trichoderma in the Rhizosphere of Coffee (Coffea arabica) Plants in Ethiopia and their Potential Use in Biocontrol of Coffee Wilt Disease 2022-01-25 Not yet
Defects in DNA double-strand break repair re-sensitise antibiotic-resistant Escherichia coli tomultiple bactericidal antibiotics 2022-01-25 Not yet
Decoding the IGF1 Signaling Gene Regulatory Network Behind Alveologenesis from A Mouse Model of Bronchopulmonary Dysplasia 2022-01-25 Not yet
DciA helicase operators exhibit diversity across bacterial phyla 2022-01-25 Not yet
Genomics-based annotations help unveil the molecular composition of edible plants 2022-01-25 Not yet
USH2A gene mutations in rabbits lead to progressive retinal degeneration and hearing loss 2022-01-25 Not yet
Multilevel Development of Cognitive Abilities in an Artificial Neural Network 2022-01-25 Not yet
Identification of putative reader proteins of 5-methylcytosine and its derivatives in Caenorhabditis elegans RNA 2022-01-25 Not yet
Manganese excess and deficiency affects photosynthesis and metabolism in Marchantia polymorpha 2022-01-25 Not yet
Harringtonine has the effects of double blocking SARS-CoV-2 membrane fusion 2022-01-25 Not yet
Structural and mechanistic basis of σ-dependent transcriptional pausing 2022-01-25 Not yet
A human DNA methylation atlas reveals principles of cell type-specific methylation and identifies thousands of cell type-specific regulatory elements 2022-01-25 Not yet
Predictive coding in ASD: inflexible weighting of prediction errors when switching from stable to volatile environments 2022-01-25 Not yet
The sowing date changed the temperature and light conditions in the field modified the cadmium content of brown rice (Oryza sativa L.) by regulating the expression of Cd-related genes 2022-01-24 Not yet
Differences in durability of PARP inhibition by clinically approved PARP inhibitors: implications for combinations and scheduling 2022-01-24 Not yet
Host Chitinase 3-like-1 is a Universal Therapeutic Target for the Delta, Omicron and Other SARS-CoV-2 Viral Variants in COVID 19 2022-01-24 Not yet
A retroviral origin of vertebrate myelin 2022-01-24 Not yet
Lysophosphatidic acid, a CSF marker in posthemorrhagic hydrocephalus that drives CSF accumulation via TRPV4-induced hyperactivation of NKCC1 2022-01-24 Not yet
Vaccinia virus attenuation by codon deoptimization of the A24R gene for vaccine development 2022-01-24 Not yet
Regional mutational signature activities in cancer genomes 2022-01-24 Not yet
Rapid Selectivity to Natural Images Across Layers of Primate V1 2022-01-24 Not yet
Nascent Polypeptide Associated Complex-alpha and Signal Recognition Particle are required for cardiac development and remodeling 2022-01-24 Not yet
Cryo-EM structure of an active central apparatus 2022-01-24 Not yet
The AAA-ATPase Atad1 and its partners promote degradation of desmin intermediate filaments in muscle 2022-01-24 Not yet
#PeerReview from @GigaScience of ???????? HTSlib - C library for reading/writing high-throughput sequencing data 2021-02-01 Not yet
Trichodesmium Erythraeum produces a higher photocurrent than other cyanobacterial species in bio-photo electrochemical cells. 2022-01-24 Not yet
Optogenetic activation of the serotonergic neural circuit between dorsal raphe nucleus and the pre-Bötzinger complex contributes to inhibition of the seizure-induced respiratory arrest in the DBA/1 mouse SUDEP model 2022-01-24 Not yet
The amyloid precursor protein modulates the position and length of the axon initial segment offering a new perspective on Alzheimer's disease genetics 2022-01-24 Not yet
#PeerReview from @GigaScience of ???????? Scientometric Trends for Coronaviruses and Other Emerging Viral Infections 2020-07-23 Not yet
#PeerReview from @GigaScience of ???????? Imputing missing RNA-seq data from DNA methylation by using transfer learning based-deep neural network 2020-04-24 Not yet
Integrated analysis reveals FOXA1 and Ku70/Ku80 as direct targets of ivermectin in prostate cancer 2022-01-23 Not yet
A highly attenuated Vesiculovax vaccine rapidly protects nonhuman primates against lethal Marburg virus challenge 2022-01-23 Not yet
Keystone species determine the productivity of synthetic microbial biofilm communities 2022-01-23 Not yet
A scalp geometry parameter-space for optimization and implementation of conventional TMS coil placement 2022-01-23 Not yet
Identification of Piperlongumine (PL) as an new E3 ligase ligand to induce targeted protein degradation 2022-01-23 Not yet
Context-aware information selection and model recommendation with ACCORDION 2022-01-23 Not yet
The relaxin receptor RXFP1 signals through a mechanism of autoinhibition 2022-01-23 Not yet
Improved production and expanded application of CVS-N2c-ΔG virus for retrograde tracing 2022-01-23 Not yet
The effector protein CgNLP1 of Colletotrichum gloeosporioides from Hevea brasiliensis disrupts nuclear localization of necrosis-induced transcription factor HbMYB8-like to suppress plant defense signaling 2022-01-23 Not yet
Glaucoma and Alzheimer: Neurodegenerative disorders show an adrenergic dysbalance 2022-01-23 Not yet
Conserved Structural Motifs in the Hammerhead Ribozyme of a Chloroplast Viroid Mimic tRNA Anticodon Structure to Hijack tRNA Ligase for Viroid Circularization 2022-01-23 Not yet
Energetic decoupling of phycobilisomes from photosystem II involved in nonphotochemical quenching in red algae 2022-01-23 Not yet
Within and among population differences in cuticular hydrocarbons in the seabird tick Ixodes uriae. 2022-01-23 Not yet
The flavonoid nobiletin exhibits differential effects on cell viability in keratinocytes exposed to UVA versus UVB radiation 2022-01-23 Not yet
On the hormonal control of posterior regeneration in the annelid Platynereis dumerilii 2022-01-23 Not yet
CRISPR-based targeted haplotype-resolved assemblies of a megabase region 2022-01-23 Not yet
EFA6R suppresses ovarian cancer cell migration and invasion 2022-01-23 Not yet
Impact of neonatal activation of nuclear receptor CAR (Nr1i3) on Cyp2 gene expression in adult mouse liver 2022-01-23 Not yet
Pharmacological inhibition of HDAC6 downregulates TGF-β via Smad2/3 acetylation and improves dystrophin-deficient muscles. 2022-01-22 Not yet
A chemical biology toolbox to investigate in-cell target engagement and specificity of PRMT5-inhibitors 2022-01-22 Not yet
Butterfly wings exhibit spatial variation in chromatin accessibility 2022-01-22 Not yet
#PeerReview from @GigaScience of ???????? Modelling genotypes in their physical microenvironment to predict single- and multi-cellular behaviour 2019-01-16 Not yet
Bacteria-mediated stabilization of murine norovirus 2022-01-22 Not yet
Macrophage activation of cGAS and TRIM5 distinguish pandemic and non-pandemic HIV 2022-01-22 Not yet
Virus-assisted directed evolution of enhanced suppressor tRNAs in mammalian cells 2022-01-22 Not yet
ESCPE-1 Mediates Retrograde Endosomal Sorting of the SARS-CoV-2 Host Factor Neuropilin-1 2022-01-22 Not yet
Ex vivo and in vivo evidence that cigarette smoke-exposed T regulatory cells impair host immunity against Mycobacterium tuberculosis 2022-01-22 Not yet
Comprehensive Evaluation of ACE2-Fc Combination with Neutralization Antibody on Broad Protection against SARS-CoV-2 and Its Variants 2022-01-22 Not yet
A new demethylase gene OsDML4 involved in high temperature induced floury endosperm formation in rice 2022-01-22 Not yet
Triplet kinase-phosphatase targeting to overcome kinase inhibitor tolerance in brain tumor cells 2022-01-22 Not yet
ECS1 and ECS2 regulate polyspermy and suppress the formation of haploid plants by promoting double fertilization 2022-01-22 Not yet
Organ Scaffold Characterizations Using Intravital Microscopy 2022-01-22 Not yet
Understanding immune-driven brain aging by human brain organoid microphysiological analysis platform 2022-01-22 Not yet
A quantitative, genome-wide analysis in Drosophila reveals transposable elements' influence on gene expression is species-specific 2022-01-22 Not yet
Brainstem somatostatin-expressing cells control the emotional regulation of pain behavior 2022-01-22 Not yet
Network architecture producing swing to stance transitions in an insect walking system 2022-01-22 Not yet
Combined multiple transcriptional repression mechanisms generate ultrasensitivity and oscillations 2022-01-22 Not yet
AbLang: An antibody language model for completing antibody sequences 2022-01-22 Not yet
Structure and Protein-Protein Interactions of Ice Nucleation Proteins Drive Their Activity 2022-01-22 Not yet
Mutations in TIC100 impair and repair chloroplast protein import and impact retrograde signalling 2022-01-22 Not yet
Staphylococcal protein A inhibits IgG-mediated phagocytosis by blocking the interaction of IgGs with FcγRs and FcRn 2022-01-22 Not yet
PopB-PcrV Interactions are Essential for Pore Formation in the Pseudomonas aeruginosa Type III Secretion System Translocon 2022-01-22 Not yet
High efficiency multiplex biallelic heritable editing in Arabidopsis using an RNA virus 2022-01-22 Not yet
An in vitro neurogenetics platform for precision disease modeling in the mouse 2022-01-21 Not yet
#PeerReview from @GigaScience of ???????? Efficient and accurate detection of splice junctions from RNAseq with Portcullis 2017-11-10 Not yet
Number neurons in the nidopallium of young domestic chicks 2022-01-21 Not yet
Environment constrains fitness advantages of division of labor in microbial consortia engineered for metabolite push or pull interactions 2022-01-21 Not yet
Pharmacometabolomics reveals urinary diacetylspermine as a biomarker of doxorubicin effectiveness in triple negative breast cancer 2022-01-21 Not yet
Behavioral and neurochemical effects of novel N-Benzyl-2-phenylethylamine derivatives in adult zebrafish 2022-01-21 Not yet
Ultra-flexible and Stretchable Intrafascicular Peripheral Nerve Recording Device with Axon-dimension, Cuff-less Microneedle Electrode Array 2022-01-21 Not yet
Adipose tissue dysfunction and visceral fat are associated to hepatic insulin resistance and severity of NASH even in lean individuals 2022-01-21 Not yet
mTOR is a Major Determinant of Chemosensitivity 2022-01-21 Not yet
Rice Pan-genome Array (RPGA): an efficient genotyping solution for pan-genome-based accelerated crop improvement in rice 2022-01-21 Not yet
Therapeutic Interruption of T Cell Development Generates High-Affinity T Cells That Escape Exhaustion and Improve Cancer Immunotherapy 2022-01-21 Not yet
Mosquito odorant receptor sensitive to natural spatial repellents and inhibitory compounds 2022-01-21 Not yet
BOS1 is a positive regulator of wounding induced cell death and plant susceptibility to Botrytis 2022-01-21 Not yet
Stabilization of E-cadherin adhesions by COX-2/GSK3β signaling is a targetable pathway in metastatic breast cancer 2022-01-21 Not yet
Immunotherapy of glioblastoma explants induces interferon-γ responses and immune cell rearrangements in tumor center, but not periphery 2022-01-21 Not yet
Quantitative proteomics of the CDK9 interactome reveals a novel function of the HSP90-CDC37-P-TEFb complex for BETi-induced HIV-1 latency reactivation 2022-01-21 Not yet
Insights into the Human Gut Virome by Sampling a Population from the Indian Subcontinent 2022-01-21 Not yet
Regulation of balanced root fungal community of Vanda falcata (Orchidaceae) by partitioning its mycorrhizal fungi and ascomycetous fungi across growth and development 2022-01-21 Not yet
Deep learning based on multi-omics integration identifies potential therapeutic targets in breast cancer 2022-01-21 Not yet
PROTAC-mediated selective degradation of cytosolic soluble epoxide hydrolase enhances ER-stress reduction 2022-01-21 Not yet
Knockout of Bbs10 results in lack of cone electrical function and progressive retinal degeneration of rods and cones 2022-01-21 Not yet
Claspin is required for growth recovery from serum starvation through regulating the PI3K-PDK1-mTOR pathway 2022-01-21 Not yet
Promoting Fc-Fc interactions between anti-capsular antibodies provides strong complement-dependent immune protection against Streptococcus pneumoniae 2022-01-21 Not yet
Ancient herpes simplex 1 genomes reveal recent viral structure in Eurasia 2022-01-21 Not yet
Sialic acid and fucose residues on the SARS-CoV-2 receptor binding domain modulate IgG reactivity 2022-01-21 Not yet
Effects of transcranial magnetic stimulation on the human brain recorded with intracranial electrocorticography: First-in-human study 2022-01-21 Not yet
The Intrinsically Disordered Region of Coronins Fine-tunes Oligomerization and Actin Polymerization 2022-01-21 Not yet
Bone marrow age dictates clonality of smooth muscle-derived cells in the atherosclerotic plaque 2022-01-21 Not yet
GM1a functions as a coreceptor/ attachment factor for Dengue virus during infection in mammalian systems 2022-01-21 Not yet
Heterogeneity in Neuronal Dynamics is Learned by Gradient Descent for Temporal Processing Tasks 2022-01-21 Not yet
Caulobacter requires anionic sphingolipids and deactivation of fur to lose lipid A 2022-01-21 Not yet
Phase separation driven by interchangeable properties in the intrinsically disordered regions of protein paralogs 2022-01-21 Not yet
Tethering designer short double-stranded RNA to mRNA for co-delivery of molecularly-targeted adjuvants and antigens towards cancer vaccination 2022-01-21 Not yet
Lysosomes are Required for Early Dorsal Signaling in the Xenopus Embryo 2022-01-20 Not yet
Cell cycle dynamics controls fluidity of the developing mouse neuroepithelium 2022-01-20 Not yet
High Hedgehog signaling is transduced by a multikinase-dependent switch controling the apico-basal distribution of the GPCR Smoothened. 2022-01-20 Not yet
Understanding the development of oral epithelial organs through single cell transcriptomic analysis 2022-01-21 Not yet
SARS-CoV-2 impairs interferon production via NSP2-induced repression of mRNA translation 2022-01-20 Not yet
The CRISPR-Cas System differentially regulates surface-attached and pellicle-biofilm in Salmonella enterica serovar Typhimurium 2022-01-21 Not yet
Controlled adhesion, membrane pinning and vesicle transport by Janus particles 2022-01-20 Not yet
Targeting SARS-CoV-2 infection through CAR T cells and bispecific T cell engagers 2022-01-20 Not yet
Exo-Enzymatic Cell-Surface Glycan Labeling for Capturing Glycan-Protein Interactions through Photo-Crosslinking 2022-01-20 Not yet
Microtubule-Inspired Functionalization of Carbon Nanotubes: A Biomimetic Carrier Design 2022-01-20 Not yet
Close kin dyads indicate intergenerational dispersal and barriers 2022-01-20 Not yet
Omicron variant of SARS-CoV-2 exhibits an increased resilience to the antiviral type I interferon response 2022-01-20 Not yet
MaxQuant and MSstats in Galaxy enable reproducible cloud-based analysis of quantitative proteomics experiments for everyone 2022-01-20 Not yet
c-Fos protein shRNA blockade in the central amygdala nucleus interfere with rats emotional reactivity on behavioral and autonomic level 2022-01-20 Not yet
In Vitro and In Vivo Pathogenicity of A. alternata to Sugar beet and Assessment of Sensitivity to Fungicides 2022-01-20 Not yet
Redefining the architecture of ferlin proteins: insights into multi-domain protein structure and function 2022-01-20 Not yet
Denoising diffusion weighted imaging data using convolutional neural networks 2022-01-20 Not yet
STAT3 regulates cytokine production downstream of TNFR1 in part by inducing expression of TNFAIP3/A20 2022-01-20 Not yet
A bivalent EBV vaccine induces neutralizing antibodies that block B and epithelial cell infection and confer immunity in humanized mice 2022-01-20 Not yet
Exploiting Color Space Geometry for Visual Stimulus Design across Animals 2022-01-20 Not yet
Selective inhibition of goal-directed actions in the mesencephalic locomotor region 2022-01-20 Not yet
Specialization in somatostatin subnetworks in sensory and association cortex 2022-01-20 Not yet
Olive mill wastewater extract as a potential mosquito larvicide 2022-01-20 Not yet
T cell response following anti COVID-19 BNT162b2 vaccination is maintained against the SARS-CoV-2 Omicron B.1.1.529 variant of concern 2022-01-20 Not yet
Membrane Stretch Gates NMDA Receptors 2022-01-20 Not yet
A deep CNN framework for neural drive estimation from HD-EMG across contraction intensities and joint angles 2022-01-20 Not yet
Plausible pathway for a host-parasite molecular replication network to increase its complexity through Darwinian evolution 2022-01-20 Not yet
Long dsRNA mediated RNA interference (dsRNAi) is antiviral in interferon competent mammalian cells 2022-01-20 Not yet
The two-component system ChvGI maintains cell envelope homeostasis in Caulobacter crescentus 2022-01-20 Not yet
Structural analysis of Red1 as a conserved scaffold of the RNA-targeting MTREC/PAXT complex 2022-01-20 Not yet
Lamin A/C phosphorylation at serine 22 is a conserved heat shock response to regulate nuclear adaptation during stress 2022-01-20 Not yet
Merkel cell polyomavirus regulates miR183 cluster and piR62011 in Merkel cell carcinoma 2022-01-20 Not yet
CDC50 orthologues in Plasmodium falciparum have distinct roles in merozoite egress and trophozoite maturation 2022-01-20 Not yet
Structural insights into G protein activation by D1 dopamine receptor 2022-01-20 Not yet
Identification of a biosynthetic gene cluster encoding a novel lanthanide chelator in Methylorubrum extorquens AM1 2022-01-20 Not yet
SARS-CoV-2 Omicron efficiently infects human airway, but not alveolar epithelium 2022-01-20 Not yet
Inflammation in the COVID-19 airway is due to inhibition of CFTR signaling by the SARS-CoV-2 Spike protein 2022-01-20 Not yet
Ex Vivo Validation of Six FDA-Approved Non-Receptor Tyrosine Kinase Inhibitors (NRTKIs) as Antivirals to Pandemic and Seasonal Influenza A Viruses 2022-01-20 Not yet
Enterococcus faecalis antagonizes Pseudomonas aeruginosa growth in polymicrobial biofilms 2022-01-20 Not yet
Dopamine ameliorates hyperglycemic memory-induced vascular dysfunction in diabetic retinopathy 2022-01-20 Not yet
Elucidating gene expression patterns across multiple biological contexts through a large-scale investigation of transcriptomic datasets 2022-01-20 Not yet
Hedgehog regulation of epithelial cell state and morphogenesis in the larynx 2022-01-20 Not yet
Differences in environmental stability among SARS-CoV-2 variants of concern: Omicron has higher stability 2022-01-19 Not yet
Impaired iron recycling from erythrocytes is an early iron-dependent hallmark of aging 2022-01-19 Not yet
Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice 2022-01-19 Not yet
Impact of pre-breeding feeding practices on rabbit mammary gland development at mid-pregnancy. 2022-01-18 Not yet
Metabolic competition between lipid metabolism and histone methylation regulates sexual differentiation in human malaria parasites. 2022-01-18 Not yet
Video based phenotyping platform for the laboratory mouse 2022-01-18 Not yet
In vitro demonstration of broad host range mobile genetic elements transferring antibiotic resistance from the human microbiome 2022-01-18 Not yet
Distinct roles for SOX2 and SOX21 in differentiation, distribution and maturation of pulmonary neuroendocrine cells 2022-01-18 Not yet
A family of C. elegans VASA homologs control Argonaute pathway specificity and promote transgenerational silencing 2022-01-18 Not yet
Elevation of Clavibacter michiganensis subsp. californiensis to species level as Clavibacter californiensis sp. nov., merging and re-classification of Clavibacter michiganensis subsp. chilensis and Clavibacter ... 2022-01-18 Not yet
Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes 2022-01-18 Not yet
De-tensioning of collagen fibers optimizes endometrial receptivity and improves the rate of embryo implantation 2022-01-18 Not yet
MicroRNA Detection in Biological Media Using a Split Aptamer Platform 2022-01-18 Not yet
ASGR1 is a candidate receptor for SARS-CoV-2 that promotes infection of liver cells 2022-01-18 Not yet
Genome-wide identification of preferentially located motifs in gene-proximal regions provides new insights into cis-regulatory sequences in plants 2022-01-18 Not yet
Supporting per-locus substitution rates improves the accuracy of species networks and avoids spurious reticulations 2022-01-18 Not yet
YAP restricts renal inflammation and mitigates kidney damage in nephronothisis related kidney disease. 2022-01-18 Not yet
Differential UBE2H-CTLH E2-E3 ubiquitylation modules regulate erythroid maturation 2022-01-18 Not yet
Dual Specificity Phosphatase 7 Drives the Formation of Cardiac Mesoderm in Mouse Embryonic Stem Cells 2022-01-18 Not yet
Wireless closed-loop smart bandage for chronic wound management and accelerated tissue regeneration 2022-01-18 Not yet
The secreted metabolome of HeLa cells under effect of Crotamine, a cell-penetrating peptide from a rattlesnake using NMR-based metabolomics analyses 2022-01-18 Not yet
The voltage-gated Cav Ca2+ channel subunit α2δ-4 is required for locomotor behavior and sensorimotor gating in mice 2022-01-17 Not yet
Basis of narrow-spectrum activity of fidaxomicin on gut pathogen Clostridioides difficile 2022-01-17 Not yet
Development of efficient RNAi methods in the corn leafhopper Dalbulus maidis, a promising application for pest control 2022-01-17 Not yet
The oncogene FOXQ1 is a selective activator of Wnt/β-catenin signalling 2022-01-17 Not yet
Human tRNA methyltransferase ALKBH8 targets wider repertoire of tRNAs and non-coding RNAs 2022-01-17 Not yet
Comparative Phenotyping of Two Commonly Used Chlamydomonas reinhardtii Background Strains: CC-1690 (21gr) and CC-5325 (the CLiP Mutant Library Background) 2022-01-17 Not yet
Blocking Kir6.2 channels with SpTx1 potentiates glucose-stimulated insulin secretion from murine pancreatic β cells and lowers blood glucose in diabetic mice 2022-01-17 Not yet
In vivo inactivation of RAD51-mediated homologous recombination leads to premature aging, but not to tumorigenesis 2022-01-17 Not yet
RT-qPCR as a screening platform for mutational and small molecule impacts on structural stability of RNA tertiary structures 2022-01-17 Not yet
piggyBac-system-mediated genomic integration of large variant libraries for deep mutational scanning in mammalian cells 2022-01-17 Not yet
The central role of the interspecific interactions in the evolution of microbial communities 2022-01-17 Not yet
Novel MBLs inhibitors screened from FDA-approved drug library restore the susceptibility of carbapenems to NDM-1-harbouring bacteria 2022-01-17 Not yet
Glycation renders alpha-synuclein oligomeric strain and modulates microglia activation 2022-01-17 Not yet
Somatodendritic release of cholecystokinin potentiates GABAergic synapses onto ventral tegmental area dopamine cells 2022-01-17 Not yet
Activity of Estrogen Receptor β Agonists in Therapy-Resistant Estrogen Receptor-Positive Breast Cancer 2022-01-17 Not yet
M-TUBE: a fabrication-free microfluidic device for large-volume bacterial electroporation requiring minimal assembly 2022-01-17 Not yet
Functional variability in adhesion and flocculation of yeast megasatellite genes 2022-01-17 Not yet
Systematic Review and Meta-Analysis: Task-based fMRI Studies in Youths with Irritability 2022-01-17 Not yet
Contrast-enhanced microCT evaluation of degeneration following partial and full width injuries to mouse lumbar intervertebral disc 2022-01-16 Not yet
Outer membrane protein A (OmpA) deficient Salmonella Typhimurium displays enhanced susceptibility towards β-lactam antibiotics: third-generation cephalosporins (ceftazidime) and carbapenems (meropenem) 2022-01-16 Not yet
Sugar shock: Probing Streptococcus pyogenes metabolism through bioluminescence imaging 2022-01-16 Not yet
NF-κB memory coordinates transcriptional responses to dynamic inflammatory stimuli 2022-01-16 Not yet
Asymmetric Pendrin Homodimer Reveals its Molecular Mechanism as Anion Exchanger 2022-01-16 Not yet
Escherichia coli response to subinhibitory concentration of Colistin: Insights from study of membrane dynamics and morphology. 2022-01-16 Not yet
Metal-binding propensity in the mitochondrial dynamin-related protein 1 2022-01-16 Not yet
Phase Separation of Shell Protein and Enzyme: An Insight into the Biogenesis of a Prokaryotic Metabolosome 2022-01-15 Not yet
Structural Basis for the Calmodulin-Mediated Activation of eEF-2K 2022-01-15 Not yet
FRET monitoring of transcription factor activities in living bacteria 2022-01-15 Not yet
Coupled abiotic-biotic cycling of nitrous oxide in tropical peatlands 2022-01-15 Not yet
Ovariectomy increases paclitaxel-induced mechanical hypersensitivity and reduces anti-inflammatory CD4+ T cells in the dorsal root ganglion of female mice 2022-01-15 Not yet
Sustained correction of hippocampal neurogenic and cognitive deficits after a brief treatment by Nutlin-3 in a mouse model of Fragile X Syndrome 2022-01-15 Not yet
Mixing genome annotation methods in a comparative analysis inflates the apparent number of lineage-specific genes 2022-01-15 Not yet
Gene regulatory evolution in cold-adapted fly populations neutralizes plasticity and may undermine genetic canalization 2022-01-15 Not yet
Codon optimality is the primary contributor to the exceptional mutational sensitivity of CcdA antitoxin in its operonic context 2022-01-15 Not yet
Phosphatidylserine within the Viral Membrane Enhances Chikungunya Virus Infectivity in a Cell-type Dependent Manner 2022-01-15 Not yet
Structural and thermodynamic analyses of the β-to-α transformation in RfaH reveal principles of fold-switching proteins 2022-01-15 Not yet
The immune synapses reveal aberrant functions of CD8 T cells during chronic HIV infection 2022-01-15 Not yet
Syndecan Regulates Cellular Morphogenesis in Cooperation with the Netrin Guidance Pathway and Rho-family GTPases 2022-01-14 Not yet
Caffeine and MDMA (ecstasy) exacerbate ER stress triggered by hyperthermia 2022-01-14 Not yet
dsRNA-induced condensation of antiviral proteins promotes PKR activation 2022-01-14 Not yet
Comparative analysis of cattle breeds as satellite cells donors for cultured beef 2022-01-14 Not yet
FRaeppli, a multispectral imaging toolbox for cell tracing and dense tissue analysis in zebrafish 2022-01-14 Not yet
High-titer production of aromatic amines in metabolically engineered Escherichia coli 2022-01-14 Not yet
Structures of LIG1 engaging with mutagenic mismatches inserted by polβ in base excision repair 2022-01-14 Not yet
Location bias contributes to functionally selective responses of biased CXCR3 agonists 2022-01-14 Not yet
Multiple UBX proteins reduce the ubiquitin threshold of the mammalian p97-UFD1-NPL4 unfoldase 2022-01-14 Not yet
Transcriptomic analysis reveals a role for the nervous system in regulating growth and development of Fasciola hepatica juveniles 2022-01-14 Not yet
The role of LHCBM1 in non-photochemical quenching in Chlamydomonas reinhardtii 2022-01-14 Not yet
SH3-domain mutations selectively disrupt Csk homodimerization or PTPN22 binding 2022-01-14 Not yet
X-linked intellectual disability mutations alter the conformational state of a histone demethylase's sensing of chromatin 2022-01-14 Not yet
Covariance predicts conserved protein residue interactions important to the emergence and continued evolution of SARS-CoV-2 as a human pathogen 2022-01-14 Not yet
Increased insula activity precedes the formation of subjective Gestalt 2022-01-14 Not yet
Multi-omic data helps improve prediction of personalised tumor suppressors and oncogenes 2022-01-14 Not yet
Multifunctional properties of Nej1XLF C-terminus promote end-joining and impact DNA double-strand break repair pathway choice 2022-01-14 Not yet
The AAA+ ATPase RavA-ViaA complex sensitizes Escherichia coli to aminoglycosides under anaerobic low energy conservation conditions 2022-01-14 Not yet
Chlorpyrifos degradation by combined solar photo-Fenton and bacterial metabolism and simultaneous toxicity analysis in zebrafish (Danio rerio) 2022-01-14 Not yet
Expressing the pro-apoptotic Reaper protein via insertion into the structural open reading frame of Sindbis virus reduces the ability to infect Aedes aegypti mosquitoes 2022-01-14 Not yet
Contextual associations represented both in neural networks and human behavior 2022-01-14 Not yet
Integrative analysis of relative abundance data and presence-absence data of the microbiome using the LDM 2022-01-14 Not yet
Limb Specific Failure of Proliferation and Translation in the Mesenchyme Leads to Skeletal Defects in Diamond Blackfan Anemia 2022-01-14 Not yet
Parallel molecular mechanisms underlie convergent evolution of the exaggerated snout phenotype in East African cichlids 2022-01-14 Not yet
Impaired spatial memory in adult vitamin D deficient BALB/c mice is associated with reductions in spine density, nitric oxide, and neural nitric oxide synthase in the hippocampus 2022-01-14 Not yet
Involvement of prelimbic cortex neurons and related circuits in the acquisition of cooperative learning by pairs of rats 2022-01-13 Not yet
Inhibition of the JAK/STAT pathway with baricitinib reduces the multiple organ dysfunction caused by hemorrhagic shock in rats 2022-01-13 Not yet
Histone chaperones exhibit conserved functionality in nucleosome remodeling 2022-01-13 Not yet
Dynamic Determinants of Quorum Quenching Mechanism Shared among N-terminal Serine Hydrolases 2022-01-13 Not yet
Deep Proteome Profiling Enabled Functional Annotation and Data-Independent Quantification of Proline Hydroxylation Targets 2022-01-13 Not yet
Enumeration of Citrus endophytic bacterial communities based on illumine metagenomics technique 2022-01-13 Not yet
Optineurin mediates delivery of membrane from transferrin receptor-positive endosomes to autophagosomes 2022-01-13 Not yet
Proteasome granular localization is regulated through mitochondrial respiration and kinase signaling 2022-01-13 Not yet
Overexpression of miR5505 enhanced drought and salt resistance in rice (Orayza sativa) 2022-01-13 Not yet
Site-specific adaptation mechanisms of an oral pathobiont in the oral and gut mucosae 2022-01-13 Not yet
The SARS-CoV-2 Omicron (B.1.1.529) variant exhibits altered pathogenicity, transmissibility, and fitness in the golden Syrian hamster model 2022-01-13 Not yet
Dynamic control systems that mimic natural regulation of catabolic pathways enable rapid production of lignocellulose-derived bioproducts 2022-01-13 Not yet
Antisense oligonucleotide-based therapeutic strategy for progranulin-deficient frontotemporal dementia 2022-01-13 Not yet
Semi-field evaluations of three botanically derived repellents against the blacklegged tick, Ixodes scapularis (Acari: Ixodidae) 2022-01-13 Not yet
An in silico method to assess antibody fragment polyreactivity 2022-01-13 Not yet
Embracing curiosity eliminates the exploration-exploitation dilemma 2022-01-13 Not yet
Comparative transcriptome investigation of Nosema ceranae infecting eastern honeybee workers 2022-01-13 Not yet
Exogenous capture accounts for fundamental differences between prosaccade and antisaccade performance 2022-01-13 Not yet
Complement facilitates developmental microglial pruning of astrocyte and vascular networks 2022-01-13 Not yet
PFTK1 kinase regulates axogenesis during development via RhoA activation. 2022-01-13 Not yet
Horizontal Transfers Lead to the Birth of Momilactone Biosynthetic Gene Clusters in Grass 2022-01-12 Not yet
Histone H3K4 methyltransferase DcATX1 promotes ethylene induced petal senescence in carnation 2022-01-12 Not yet
Real time, in vivo measurement of neuronal and peripheral clocks in Drosophila melanogaster 2022-01-12 Not yet
Improved biodiversity detection using a large-volume environmental DNA sampler with in situ filtration and implications for marine eDNA sampling strategies 2022-01-12 Not yet
The Mechanisms of GPR55 Receptor Functonal Selectivity 2022-01-12 Not yet
Propofol anesthesia alters cortical traveling waves 2022-01-12 Not yet
Repeated toxic injuries of murine liver are tolerated through microsteatosis and mild inflammation 2022-01-12 Not yet
Phenotypic and transcriptomic analysis reveals early stress responses in transgenic rice expressing Arabidopsis DREB1a 2022-01-12 Not yet
A split ribozyme that links detection of a native RNA to orthogonal protein outputs 2022-01-12 Not yet
Favipiravir, umifenovir and camostat mesylate: a comparative study against SARS-CoV-2 2022-01-12 Not yet
Tissue fibroblasts are a critical source of prostacyclin and anti-thrombotic 2022-01-12 Not yet
Effect of cannabidiol on apoptosis and cellular interferon and interferon-stimulated gene responses to the SARS-CoV-2 genes ORF8, ORF10 and M protein 2022-01-12 Not yet
Hemagglutinin stability determines influenza A virus susceptibility to a broad-spectrum fusion inhibitor Arbidol 2022-01-12 Not yet
Potentiation of drug toxicity through virus latency reversal promotes preferential elimination of HIV infected cells 2022-01-12 Not yet
Lightweight compositional analysis of metagenomes with FracMinHash and minimum metagenome covers 2022-01-12 Not yet
A bacterial secretosome for regulated envelope biogenesis and quality control 2022-01-12 Not yet
Evolution under juvenile malnutrition impacts adult metabolism and fitness 2022-01-12 Not yet
Ablation of SAMD1 in Mice Causes Failure of Angiogenesis, Embryonic Lethality 2022-01-12 Not yet
Evolution of a cis-acting SNP that controls Type VI Secretion in Vibrio cholerae 2022-01-12 Not yet
RNA-based therapy for Cryptosporidium parvum infection: proof-of-concept studies 2022-01-12 Not yet
Localized Cardiolipin Synthesis is Required for the Assembly of MreB During the Polarized Cell Division of Chlamydia trachomatis 2022-01-12 Not yet
"Learning in reverse: Dopamine errors drive excitatory and inhibitory components of backward conditioning in an outcome-specific manner". 2022-01-12 Not yet
SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike-ACE2 receptor interaction 2022-01-12 Not yet
Pathological relevance of post-translationally modified alpha-synuclein (pSer87, pSer129, nTyr39) in idiopathic Parkinson's disease and Multiple System Atrophy. 2022-01-12 Not yet
Magnetic Temporal Interference for Noninvasive Focal Brain Stimulation 2022-01-12 Not yet
Rational design yields molecular insights on leaf binding of the anchor peptide Macaque Histatin 2022-01-12 Not yet
Single-nucleus RNA-seq of normal-appearing brain regions in relapsing-remitting vs. secondary progressive multiple sclerosis 2022-01-12 Not yet
Astrogliosis mapping in individual brains using multidimensional MRI 2022-01-12 Not yet
Magnetic Stimulation Allows Focal Activation of the Mouse Cochlea 2022-01-12 Not yet
SLC38A2 provides